A Phototransistor-Based High-Sensitivity Biosensing System Using 650-nm Light

IEEE Sensors Journal

Volumn 9, Issue 6, 2009, Pages 673-677

  Chang, Yu Wei ^a   Tai, Yu Ting ^a   Yang, Yuh Shyong ^a   Huang, Yang Tung ^a  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

Author keywords

Biomedical transducers; medical diagnosis; photodetectors; phototransistors

Indexed keywords

EID: 85008016215     PISSN: 1530437X     EISSN: 15581748     Source Type: Journal    
DOI: 10.1109/JSEN.2009.2020675     Document Type: Article

References (15)

1. R. A. Yotter, L. A. Lee, and D. M. Wilson, “Sensor technologies for monitoring metabolic activity in single cells—Part I: Optical methods”, IEEE Sensors J., vol. 4, no. 4, pp. 395–411, Aug. 2004.
2. R. Eisenthal and M. J. Danson, Enzyme Assays: A Practical Approach, 2nd ed. Oxford, U.K.: Oxford Univ. Press, 2002.
3. N. C. Veitch, “Horseradish peroxidase: A modern view of a classic enzyme”, Phytochemistry, vol. 65, pp. 249–259, 2004.
4. W.-J. Ho, J.-S. Chen, M.-D. Ker, T.-K. Wu, C.-Y. Wu, Y.-S. Yang, Y.-K. Li, and C.-J. Yuan, “Fabrication of a miniature CMOS-based optical biosensor”, Biosens. Bioelectron., vol. 22, pp. 3008–3013,2007.
5. Y.-W. Chang, P.-C. Yu, Y.-T. Huang, and Y.-S. Yang, “A CMOS-compatible optical biosensing system based on visible absorption spectroscopy”, in Proc. IEEE Int. Conf. Electron Devices and Solid-State Circuits, 2007, vol. 2, pp. 1099–1102.
6. P. D. Josephy, T. Eling, and R. P. Mason, “The horseradish peroxidase-catalyzed oxidation of 3,5,3’,5’-tetramethylbenzidine”, J. Biol. Chem., vol. 257, pp. 3669–3675, 1982.
7. S. Donati, Photodetectors: De-vices, Circuits, and Applications. Englewood Cliffs, NJ: Prentice-Hall, 2000.
8. S.-H. Huang, Y.-C. Shih, C.-Y. Wu, C.-J. Yuan, Y.-S. Yang, Y.-K. Li, and T.-K. Wu, “Detection of serum uric acid using the optical polymeric enzyme biochip system”, Biosens. Bioelectron., vol. 19, pp. 1627–1633, 2004.
9. H. Zimmermamn, Integrated Silicon Optoelectronics. New York: Springer, 2000.
10. S. M. Sze and K. K. NG, Physics of SemiconductorDevices, 3rd ed. New York: Wiley, 2007.
11. E.S. Bos, A. A. van derDoelen, N. van Rooy, and A. H. W. M. Schuurs, “3,3’, 5,5’-tetramethylbenzidine as an ames test negative chromogen for horse-radish peroxidase in enzyme-immunoassay”, J. Immunoassay and Immunochemistry, vol. 2, pp. 187–204, 1981.
12. P. Fanjul-Bolado, M. B. Gonzălez-Garcia, and A. Costa-Garcia, “Amperometric detection in TMB/HRP-based assays”, Anal. Bioanal. Chem., vol. 382, pp. 297–302, 2005.
13. B. Mecheri, L. Piras, L. Ciotti, and G. Caminati, “Electrode coating with ultrathin films containing electroactive molecules for biosensor applications”, IEEE Sensors J.,vol.4,no.2,pp. 171–179, Apr. 2004.
14. M. Schanz, W. Brockherde, R. Hauschild, B. J. Hosticka, and A. Teuner, “CMOS photosensor arrays with on-chip signal processing”, in Proc. Eur. Solid-State Circuits Conf., 1997, pp. 236–239.
15. A. C. Pimentel, A. T. Pereira, V. Chu, D. M. F. Prazeres, and J. P. Conde, “Detection of chemiluminescence using an amorphous silicon photodiode”, IEEE Sensors J., vol. 7, no. 3, pp. 415–416, Mar. 2007.