Studies on the Mechanism of Action of Saikosaponin: 1. Effects of saikosaponin to hepatic injury induced by D-galactosamine

Kanzo

Volumn 19, Issue 5, 1978, Pages 430-435

  Arichi, Shigeru ^a   Konishi, Hiroyoshi ^a   Abe, Hiroko ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85007849868     PISSN: 04514203     EISSN: 18813593     Source Type: Journal    
DOI: 10.2957/kanzo.19.430     Document Type: Article

References (10)

1. Crude Saikosaides 89: 712, 1969.
2. Crude Saikosaides 89: 1367, 1969.
3. Yamamoto, M. & Kumagai, A. et al.: Structure and action of saikosaponins isolated from Bupleurum falcatum L., Arzneim Forsch. (Drug Res.), 25, Nr. 7: 1021, 1975.
4. Keppler, D. & Lesh, R. et al.: Experimental hepatitis induced by D-galactosamine. Exp. Mol. Pathol., 9: 279, 1968.
5. Keppler, D. & Decker, D.: Studies on the mechanism of galactosamine hepatitis, Accumulation of galactosamine-1-phosphate and its inhibition of UDP-glucose pyrophos-phorylase. European J. Biochem., 10: 219, 1969.
6. Koff, R.S. & Gordon, G. et al.: D-galactosamine hepatitis, 1. Hepatocellular injury and fatty liver following a single dose. Proc. Soc. Exp. Biol. Med., 137: 696, 1971.
7. Kubota, T. & Tonami, F. et al.: The structure of saikogenins A, B, C and D. Triterpenoid alcohols of Bupleurum falcatum L. Tetrahedron Letters, 701, 1966.
8. Abe, H. & Konishi, H. et al.: In preparation.
9. Koff, R.S. & Davidson, L.J. et al.: D-galactosamine hepatotoxicity. Normoactive smooth endoplasmic reticulum and modification by phenobarbital. Exp. Mol. Pathol., 19: 168, 1973.
10. Abe, H. & Sakaguchi, M. et al.: In preparation.