Uncertainty about clinical equipoise

BMJ

Volumn 322, Issue 7289, 2001, Pages 795-

  Gifford, Fred ^a   Lilford, R J ^b   Benjamin, Djulbegovic ^b   Sackett, David L ^c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c Trout Research and Education Centre at Irish Lake   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL AND BEHAVIORAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DECISION SUPPORT SYSTEM; HUMAN; MEDICAL ETHICS; METHODOLOGY; NOTE; PATIENT SELECTION; PROBABILITY; RANDOMIZED CONTROLLED TRIAL; STANDARD; UNCERTAINTY;

BIOMEDICAL AND BEHAVIORAL RESEARCH;

DECISION SUPPORT TECHNIQUES; ETHICS, MEDICAL; HUMANS; PATIENT SELECTION; PROBABILITY; RANDOMIZED CONTROLLED TRIALS; UNCERTAINTY;

EID: 85007671041     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.322.7289.795     Document Type: Letter

References (11)

1. Weijer C, Shapiro S, Glass K, Enkin M. For and against: Clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial. BMJ 2000; 321: 756–758. (23 September.)
2. Gifford F. Community equipoise and the ethics of randomized clinical trials. Bioethics 1995; 9: 127–148.
3. Gifford F. Freedman's ‘clinical equipoise’ and sliding-scale all dimensions considered equipoise. J Med Philosophy 2000; 25: 399–426.
4. Weijer C, Shapiro S, Glass K, Enkin M. For and against: Clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial. BMJ 2000; 321: 756–758. (23 September.)
5. Djulbegovic B, Lacevic M, Cantor A, Fields K, Bennett C, Adams J, et al. The uncertainty principle and industry-sponsored research. Lancet 2000; 356: 635–638.
6. Edwards SJL, Lilford RJ, Braunholtz DA, Jackson JC, Hewison J, Thornton J. Ethical issues in the design and conduct of randomized controlled trials. Health Technol Assessment 1998; 2(15): 1–130.
7. Lilford RJ, Jackson J. Equipoise and the ethics of randomization. J R Soc Med 1995; 88: 552–559.
8. Bradford Hill A. Medical ethics and controlled trials. BMJ 1963; 2: 1043–1049.
9. Weijer C, Shapiro S, Glass K, Enkin M. For and against: Clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial. BMJ 2000; 321: 756–758. (23 September.)
10. Shapiro SC, Glass JK. Why Sackett's analysis of randomized controlled trials fails, but needn't. Can Med Assoc J 2000; 163: 834–835.
11. Sackett DL. Equipoise, a term whose time (if it ever came) has surely gone. Can Med Assoc J 2000; 163: 835–836.