Expression of KIR2DS1 by decidual natural killer cells increases their ability to control placental HCMV infection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 52, 2016, Pages 15072-15077

  Crespo, Ângela C ^a,b   Strominger, Jack L ^a   Tilburgs, Tamara ^a  

^a Harvard University   (United States)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

HLA C; Human; Immune tolerance; Pregnancy; Trophoblast

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULYSIN; GRANZYME B; HLA C ANTIGEN; HLA C2 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS1; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2C; PERFORIN; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; IMMUNOGLOBULIN; KIR2DS1 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOMEGALOVIRUS INFECTION; DECIDUA; DECIDUAL STROMAL CELL; DEGRANULATION; EXTRAVILLOUS TROPHOBLAST; FEMALE; FETUS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; MOLECULAR PATHOLOGY; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NORMAL HUMAN; PLACENTA; PLACENTA DISORDER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STROMA CELL; TROPHOBLAST; CELL SEPARATION; CYTOMEGALOVIRUS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; METABOLISM; PLACENTA DEVELOPMENT; PREGNANCY; PREGNANCY COMPLICATION; PREGNANCY OUTCOME; VIROLOGY;

CELL SEPARATION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DECIDUA; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HLA-C ANTIGENS; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULINS; KILLER CELLS, NATURAL; PLACENTA; PLACENTATION; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY OUTCOME; RECEPTORS, KIR; TROPHOBLASTS;

EID: 85007448567     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1617927114     Document Type: Article

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