Metabolic engineering of Klebsiella pneumoniae based on in silico analysis and its pilot-scale application for 1,3-propanediol and 2,3-butanediol co-production

Journal of Industrial Microbiology and Biotechnology

Volumn 44, Issue 3, 2017, Pages 431-441

  Park, Jong Myoung ^a   Rathnasingh, Chelladurai ^a   Song, Hyohak ^a  

^a GS Caltex Corporation   (South Korea)

Author keywords

1,3 Propanediol; 2,3 Butanediol; 5000 L bioreactor; In silico; Klebsiella pneumoniae; Pilot scale fermentation

Indexed keywords

1,3 PROPANEDIOL; 2,3 BUTANEDIOL; FUMARIC ACID; GLYCEROL; MALATE DEHYDROGENASE; MALIC ACID; OXALOACETIC ACID; PYRUVIC ACID; SUCCINIC ACID; 1,3-PROPANEDIOL; 2,3-BUTYLENE GLYCOL; BUTANEDIOL; PROPANEDIOL DERIVATIVE;

ARTICLE; BACTERIAL STRAIN; CELL GROWTH; COMPUTER MODEL; CONTROLLED STUDY; FED BATCH FERMENTATION; KLEBSIELLA PNEUMONIAE; METABOLIC ENGINEERING; NONHUMAN; OXYGEN CONSUMPTION; STRAIN IMPROVEMENT; BATCH CELL CULTURE; BIOREACTOR; CHEMISTRY; CULTURE MEDIUM; FERMENTATION; GENE INACTIVATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PILOT STUDY; TRANSGENIC MICROORGANISM;

BATCH CELL CULTURE TECHNIQUES; BIOREACTORS; BUTYLENE GLYCOLS; CULTURE MEDIA; FERMENTATION; GENE KNOCKOUT TECHNIQUES; GLYCEROL; INDUSTRIAL MICROBIOLOGY; KLEBSIELLA PNEUMONIAE; METABOLIC ENGINEERING; MICROORGANISMS, GENETICALLY-MODIFIED; PILOT PROJECTS; PROPYLENE GLYCOLS;

EID: 85007425810     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-016-1898-4     Document Type: Article

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