Effects of 2 years of exercise on gait impairment in people with Parkinson Disease: The PRET-PD randomized trial

Journal of Neurologic Physical Therapy

Volumn 41, Issue 1, 2017, Pages 21-30

  Rafferty, Miriam R ^a   Prodoehl, Janey ^c   Robichaud, Julie A ^d   David, Fabian J ^b   Poon, Cynthia ^b   Goelz, Lisa C ^e   Vaillancourt, David E ^f   Kohrt, Wendy M ^g   Comella, Cynthia L ^h   Corcos, Daniel M ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c MIDWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM   (United States)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^f UNIVERSITY OF FLORIDA   (United States)

^g UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^h RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Human movement system; Plantarflexors; Progressive resistance exercise; Randomized controlled trial; Walking

Indexed keywords

AGED; COMPLICATION; CONTROLLED STUDY; HUMAN; KINESIOTHERAPY; MIDDLE AGED; NEUROLOGIC GAIT DISORDER; PARKINSON DISEASE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING;

AGED; EXERCISE THERAPY; GAIT DISORDERS, NEUROLOGIC; HUMANS; MIDDLE AGED; PARKINSON DISEASE; PROSPECTIVE STUDIES; RESISTANCE TRAINING;

EID: 85007318068     PISSN: 15570576     EISSN: 15570584     Source Type: Journal    
DOI: 10.1097/NPT.0000000000000163     Document Type: Article

References (42)

1. de Lau LM, Breteler MM. Epidemiology of Parkinson's disease. Lancet Neurol. 2006;5(6):525-535.
2. Stewart KC, Fernandez HH, Okun MS, Jacobson CE, Hass CJ. Distribution of motor impairment influences quality of life in Parkinson's disease. Mov Disord. 2008;23(10):1466-1468.
3. Lo RY, Tanner CM, Albers KB, et al. Clinical features in early Parkinson disease and survival. Arch Neurol. 2009;66(11):1353-1358.
4. Rascol O, Payoux P, Ory F, Ferreira JJ, Brefel-Courbon C, Montastruc JL. Limitations of current Parkinson's disease therapy. Ann Neurol. 2003;53(suppl 3):S3-S12; discussion S12-S15.
5. Pötter-Nerger M, Volkmann J. Deep brain stimulation for gait and postural symptoms in Parkinson's disease. Mov Disord. 2013;28(11): 1609-1615.
6. McNeely ME, Duncan RP, Earhart GM. Medication improves balance and complex gait performance in Parkinson disease. Gait Posture. 2012;36(1):144-148.
7. Blin O, Ferrandez AM, Pailhous J, Serratrice G. Dopa-sensitive and dopa-resistant gait parameters in Parkinson's disease. J Neurol Sci. 1991;103(1):51-54.
8. Rochester L, Baker K, Nieuwboer A, Burn D. Targeting dopa-sensitive and dopa-resistant gait dysfunction in Parkinson's disease: selective responses to internal and external cues. Mov Disord. 2011;26(3):430-435.
9. Schaafsma JD, Giladi N, Balash Y, Bartels AL, Gurevich T, Hausdorff JM. Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa. J Neurol Sci. 2003;212(1-2): 47-53.
10. McNeely ME, Earhart GM. Medication and subthalamic nucleus deep brain stimulation similarly improve balance and complex gait in Parkinson disease. Parkinsonism Relat Disord. 2013;19(1):86-91.
11. Rocha PA, Porfírio GM, Ferraz HB, Trevisani VF. Effects of external cues on gait parameters of Parkinson's disease patients: a systematic review. Clin Neurol Neurosurg. 2014;124:127-134.
12. Mehrholz J, Friis R, Kugler J, Twork S, Storch A, Pohl M. Treadmill training for patients with Parkinson's disease. Cochrane Database Syst Rev. 2010(1):CD007830.
13. Scandalis TA, Bosak A, Berliner JC, Helman LL, Wells MR. Resistance training and gait function in patients with Parkinson's disease. Am J Phys Med Rehabil. 2001;80(1):38-43; quiz 44-36.
14. Hackney ME, Earhart GM. Effects of dance on gait and balance in Parkinson's disease: a comparison of partnered and nonpartnered dance movement. Neurorehabil Neural Repair. 2010;24(4):384-392.
15. Li F, Harmer P, Fitzgerald K, et al. Tai chi and postural stability in patients with Parkinson's disease. N Engl J Med. 2012;366(6): 511-519.
16. Wassom DJ, Lyons KE, Pahwa R, Liu W. Qigong exercise may improve sleep quality and gait performance in Parkinson's disease: a pilot study. Int J Neurosci. 2015;125(8):578-584.
17. Dibble LE, Hale TF, Marcus RL, Gerber JP, LaStayo PC. High intensity eccentric resistance training decreases bradykinesia and improves quality of life in persons with Parkinson's disease: a preliminary study. Parkinsonism Relat Disord. 2009;15(10):752-757.
18. Hass CJ, Buckley TA, Pitsikoulis C, Barthelemy EJ. Progressive resistance training improves gait initiation in individuals with Parkinson's disease. Gait Posture. 2012;35(4):669-673.
19. Corcos DM, Robichaud JA, David FJ, et al. A two-year randomized controlled trial of progressive resistance exercise for Parkinson's disease. Mov Disord. 2013;28(9):1230-1240.
20. Prodoehl J, Rafferty MR, David FJ, et al. Two-year exercise program improves physical function in Parkinson's disease: the PRET-PD randomized clinical trial. Neurorehabil Neural Repair. 2015;29(2):112-122.
21. Allen NE, Sherrington C, Canning CG, Fung VS. Reduced muscle power is associated with slower walking velocity and falls in people with Parkinson's disease. Parkinsonism Relat Disord. 2010;16(4):261-264.
22. Pang MY, Mak MK. Influence of contraction type, speed, and joint angle on ankle muscle weakness in Parkinson's disease: implications for rehabilitation. Arch Phys Med Rehabil. 2012;93(12):2352-2359.
23. Schilling BK, Karlage RE, LeDoux MS, Pfeiffer RF, Weiss LW, Falvo MJ. Impaired leg extensor strength in individuals with Parkinson disease and relatedness to functional mobility. Parkinsonism Relat Disord. 2009;15(10):776-780.
24. Albani G, Sandrini G, Künig G, et al. Differences in the EMG pattern of leg muscle activation during locomotion in Parkinson's disease. Funct Neurol. 2003;18(3):165-170.
25. Dietz V, Colombo G. Influence of body load on the gait pattern in Parkinson's disease. Mov Disord. 1998;13(2):255-261.
26. Zhang TY, Hu Y, Nie ZY, et al. Effects of tai chi and multimodal exercise training on movement and balance function in mild to moderate idiopathic Parkinson Disease. Am J Phys Med Rehabil. 2015;94(10 suppl 1): 921-929.
27. Cianci H. Parkinson's Disease: Fitness Counts. 3rd ed. Miami, FL: National Parkinson Foundation; 2006.
28. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55(3):181-184.
29. Valls-Solé J, Pascual-Leone A, Brasil-Neto JP, Cammarota A, McShane L, Hallett M. Abnormal facilitation of the response to transcranial magnetic stimulation in patients with Parkinson's disease. Neurology. 1994;44(4):735-741.
30. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
31. Langston JW, Widner H, Goetz CG, et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord. 1992;7(1): 2-13.
32. David FJ, Robichaud JA, Leurgans SE, et al. Exercise improves cognition in Parkinson's disease: the PRET-PD randomized, clinical trial. Mov Disord. 2015;30(12):1657-1663.
33. Sturman MM, Vaillancourt DE, Metman LV, Bakay RA, Corcos DM. Effects of five years of chronic STN stimulation on muscle strength and movement speed. Exp Brain Res. 2010;205(4): 435-443.
34. Vaillancourt DE, Prodoehl J, Sturman MM, Bakay RA, Metman LV, Corcos DM. Effects of deep brain stimulation and medication on strength, bradykinesia, and electromyographic patterns of the ankle joint in Parkinson's disease. Mov Disord. 2006;21(1):50-58.
35. Portney LG, Watkins MP. Foundations of Clinical Research: Applications to Practice. 3rd ed. Upper Saddle River, NJ: Pearson Education, Inc; 2009.
36. Combs SA, Diehl MD, Filip J, Long E. Short-distance walking speed tests in people with Parkinson disease: reliability, responsiveness, and validity. Gait Posture. 2014;39(2):784-788.
37. Steffen T, Seney M. Test-retest reliability and minimal detectable change on balance and ambulation tests, the 36-item short-formhealth survey, and the unified Parkinson disease rating scale in people with parkinsonism. Phys Ther. 2008;88(6):733-746.
38. Lim LI, van Wegen EE, de Goede CJ, et al. Measuring gait and gaitrelated activities in Parkinson's patients own home environment: a reliability, responsiveness and feasibility study. Parkinsonism Relat Disord. 2005;11(1):19-24.
39. Hass CJ, Bishop M, Moscovich M, et al. Defining the clinicallymeaningful difference in gait speed in persons with Parkinson disease. J Neurol Phys Ther. 2014;38(4):233-238.
40. King LA, Peterson DS, Mancini M, et al. Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson disease: a randomized clinical trial. BMC Neurol. 2015;15:218.
41. King LA, Priest KC, Nutt J, et al. Comorbidity and functional mobility in persons with Parkinson disease. Arch Phys Med Rehabil. 2014;95(11):2152-2157.
42. Frazzitta G, Maestri R, Bertotti G, et al. Intensive rehabilitation treatment in early Parkinson's disease: a randomized pilot study with a 2-year follow-up. Neurorehabil Neural Repair. 2015;29(2): 123-131.