Inhalation dosimetry modeling provides insights into regional respiratory tract toxicity of inhaled diacetyl

Toxicology

Volumn 388, Issue , 2017, Pages 30-39

  Cichocki, Joseph A ^a   Morris, John B ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

2,3 Butanedione; Diacetyl; Inhalation dosimetry

Indexed keywords

2,3 BUTANEDIONE; FLAVORING AGENT;

ARTICLE; BRONCHUS; COMPARATIVE STUDY; COMPUTATIONAL FLUID DYNAMICS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSIMETRY; EXPOSURE; HUMAN; LUNG TOXICITY; MATHEMATICAL MODEL; MOUTH BREATHING; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT INJURY; TOXIC INHALATION; TRACHEA; VAPOR; VAPOR PRESSURE; ADVERSE EFFECTS; ANIMAL; BIOLOGICAL MODEL; DOSE RESPONSE; DRUG EFFECTS; HYDRODYNAMICS; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; OCCUPATIONAL EXPOSURE; PROCEDURES; RESPIRATORY SYSTEM; RISK ASSESSMENT; SPECIES DIFFERENCE; TOXICITY TESTING;

ADMINISTRATION, INHALATION; ANIMALS; DIACETYL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVORING AGENTS; HUMANS; HYDRODYNAMICS; INHALATION EXPOSURE; MODELS, BIOLOGICAL; OCCUPATIONAL EXPOSURE; RATS; RESPIRATORY SYSTEM; RISK ASSESSMENT; SPECIES SPECIFICITY; TOXICITY TESTS;

EID: 85007236837     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2016.11.007     Document Type: Article

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