Mesenchymal stem cells: A modern approach to treat long bones defects

IFMBE Proceedings

Volumn 16, Issue 1, 2007, Pages 253-256

  Krečič Stres, Hana ^a   Krkovic M ^b   Koder, J ^b   Malicev E ^c   Drobnic M ^b   Marolt, D ^c,d   Kregar Velikonja, N ^a  

^a Educell Doo   (Slovenia)

^b UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^c BLOOD TRANSFUSION CENTRE OF SLOVENIA   (Slovenia)

^d Department of Earth and Environmental Sciences   (United States)

Author keywords

BMSC; Bone healing; Bone marrow; Long bone defects; Mesenchymal stem cells; Tissue engineering

Indexed keywords

CALCIUM COMPOUNDS; CELL CULTURE; CELL ENGINEERING; PATIENT TREATMENT; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE; TISSUE ENGINEERING;

BMSC; BONE HEALING; BONE MARROW; LONG BONE; MESENCHYMAL STEM CELL;

BONE;

EID: 85007062085     PISSN: 16800737     EISSN: 14339277     Source Type: Conference Proceeding    
DOI: 10.1007/978-3-540-73044-6_63     Document Type: Conference Paper

References (14)

1. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD et al. (1999) Multilineage potential of mesenchymal stem cells. Science 284:143-147
2. Flanagan N (2001) Advances in stem cell therapy. Genetic Engineering News 21(9):1,29,61,66
3. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH (2001) Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7(2):211-228
4. Bianco P, Riminucci M, Gronthos S, Robey PG (2001) Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19(3):180-192
5. Heller L, Scot LL (2001) Bone and soft tissue reconstruction. In: Bucholz RW, Heckmann JD Fractures in Adults. Lippincot Williams & Wilkins, New York
6. Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP (1997) Osteogenic differentiation of purified, culture expanded human MSC in vitro. J Cell Biochem 64:295-312
7. Meinel L, Hofmann S, Karageorgiou V, Zichner L, Langer R, Kaplan D et al. (2004) Engineering cartilage-like tissue using human mesenchymal stem cells and silk scaffolds. Biotech Bioeng 88:688-698
8. Martin I, Muraglia A, Campanile G, A Cancedda, Quarto R (2006) Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow. Endo 138(10):4456-4462
9. Fatkhudinov TK, Gol’dshtein DV, Pulin AA, Shamenkov DA, Rzhaninova AA, Gornostaeva SA, Grigor’yan AS, Kulakov AA (2005) Reparative osteogenesis during transplantation of mesenchymal stem cells. Bull Exp Biol Med 40(1):96-99
10. Carter DR, Beaupre GS, Giori NJ, Helms JA (1998) Mechanobiology of Skeletal Regeneration. Clin Orthop Rel Res, S41-55
11. Quarto R, Mastrogiacomo M, Cancedda R, Ketepov SM, Mukhachev V et al. (2001) Repair of long bone defects with the use of autologous bone marrow stromal cells. N Eng J Med 344(5):385-386
12. Kadiyala S, Jaiswal N, Bruder SP (1997) Culture-expanded, bone marrow-derived mesenchymal stem cells can regenerate a critical sized segmental bone defect. Tissue Eng 3(2):173-185
13. Orozco L, Rodriguez L, Torrico C, Douville J, Hock JM, Armstrong RD etal. (2005) Clinical feasibility study: The use of cultured enriched autologous bone marrow cells to treat refractory atrophic and hypotrophic nonunion fractures at http://scholar.google.com/scholar?hl=en&lr=&q=cache:ss358GFA5X cJ:www.aastrom.com/pdf/Whitepaper_Barcelona-051205.pdf+Orozco+clinical+feasibility
14. Hernandez Alfaro (2005) Clinical feasibility study: The use of cultured autologous bone marrow – derived Tissue repair cells (TRC) for maxillary sinus floor au gmentation in edetulous humans at http://www.aastrom.com/corporate/bone.cfm?pagesect=SinusLift