Blocking virus replication during acute murine cytomegalovirus infection paradoxically prolongs antigen presentation and increases the CD8+ T cell response by preventing type I IFN-dependent depletion of dendritic cells

Journal of Immunology

Volumn 198, Issue 1, 2017, Pages 383-393

  Loo, Christopher P ^a   Snyder, Christopher M ^b   Hill, Ann B ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CROSS PRESENTATION; CYTOKINE RESPONSE; CYTOMEGALOVIRUS INFECTION; DENDRITIC CELL; IMMUNOMODULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS LOAD; VIRUS REPLICATION; ADOPTIVE TRANSFER; ANIMAL; CELL SEPARATION; DISEASE MODEL; HERPES VIRUS INFECTION; IMMUNOLOGY; MUROMEGALOVIRUS;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CROSS-PRIMING; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; HERPESVIRIDAE INFECTIONS; INTERFERON TYPE I; MICE; MUROMEGALOVIRUS; VIRUS REPLICATION;

EID: 85007007706     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600478     Document Type: Article

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