Immunogenicity and protective efficacy of a single-dose live non-pathogenic Escherichia coli oral vaccine against F4-positive enterotoxigenic Escherichia coli challenge in pigs

Vaccine

Volumn 35, Issue 2, 2017, Pages 353-360

  Fairbrother, John Morris ^a   Nadeau, Éric ^b   Bélanger, Louise ^b   Tremblay, Cindy Love ^b   Tremblay, Danielle ^b   Brunelle, Mélanie ^b   Wolf, Regina ^c   Hellmann, Klaus ^c   Hidalgo, Álvaro ^d  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Prevtec microbia   (Canada)

^c Klifovet AG   (Germany)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

Enterotoxigenic Escherichia coli; F4 (K88) fimbriae; Immune response; Live vaccine; Pig; Post weaning diarrhea

Indexed keywords

BACTERIAL PROTEIN; BACTERIUM ANTIBODY; ESCHERICHIA COLI VACCINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LIVE VACCINE; PROTEIN F4; UNCLASSIFIED DRUG; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; PLACEBO;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL SHEDDING; BACTERIAL STRAIN; CECUM; COLON; CONTROLLED STUDY; DIARRHEA; DISEASE DURATION; DISEASE SEVERITY; DRUG EFFICACY; ENTEROTOXIGENIC ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; FEMALE; FIMBRIA; ILEUM; IMMUNE RESPONSE; IMMUNOGENICITY; INTESTINE FLUID; JEJUNUM; MALE; NONHUMAN; PIG; POST WEANING DIARRHEA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RECTUM; SINGLE DRUG DOSE; VACCINATION; WEIGHT GAIN; ANIMAL; ANTIBODY PRODUCTION; BLOOD; IMMUNOLOGY; INTESTINE; MICROBIOLOGY; ORAL DRUG ADMINISTRATION; PATHOLOGY; SERUM; SWINE DISEASE; TREATMENT OUTCOME; VETERINARY;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; BACTERIAL SHEDDING; DIARRHEA; ENTEROTOXIGENIC ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI VACCINES; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; INTESTINES; PLACEBOS; SERUM; SWINE; SWINE DISEASES; TREATMENT OUTCOME; VACCINES, ATTENUATED;

EID: 85007003511     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2016.11.045     Document Type: Article

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