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Volumn 1, Issue 1, 2014, Pages

Lorcaserin for the treatment of obesity? A closer look at its side effects

Author keywords

[No Author keywords available]

Indexed keywords

LORCASERIN; PLACEBO; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR;

EID: 85006961447     PISSN: None     EISSN: 20533624     Source Type: Journal    
DOI: 10.1136/openhrt-2014-000173     Document Type: Editorial
Times cited : (32)

References (21)
  • 1
    • 33845765243 scopus 로고    scopus 로고
    • What are the latest figures for state-specific prevalence of obesity in the United States
    • Marcason W. What are the latest figures for state-specific prevalence of obesity in the United States J Am Diet Assoc 2007;107:168.
    • (2007) J Am Diet Assoc , vol.107 , pp. 168
    • Marcason, W.1
  • 2
    • 60149100157 scopus 로고    scopus 로고
    • Trends in obesity among adults in England from 1993 to 2004 by age and social class and projections of prevalence to 2012
    • Zaninotto P, Head J, Stamatakis E, et al. Trends in obesity among adults in England from 1993 to 2004 by age and social class and projections of prevalence to 2012. J Epidemiol Community Health 2009;63:140-6.
    • (2009) J Epidemiol Community Health , vol.63 , pp. 140-146
    • Zaninotto, P.1    Head, J.2    Stamatakis, E.3
  • 3
    • 44349123948 scopus 로고    scopus 로고
    • Rise in childhood obesity with persistently high rates of undernutrition among urban school-aged Indo-Asian children
    • Jafar TH, Qadri Z, Islam M, et al. Rise in childhood obesity with persistently high rates of undernutrition among urban school-aged Indo-Asian children. Arch Dis Child 2008;93:373-8.
    • (2008) Arch Dis Child , vol.93 , pp. 373-378
    • Jafar, T.H.1    Qadri, Z.2    Islam, M.3
  • 5
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2008
    • Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010;303:235-41.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3
  • 6
    • 66149137211 scopus 로고    scopus 로고
    • The preventable causes of death in the United States: Comparative risk assessment of dietary, lifestyle, and metabolic risk factors
    • Danaei G, Ding EL, Mozaffarian D, et al. The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLoS Med 2009;6:e1000058.
    • (2009) PLoS Med , vol.6 , pp. e1000058
    • Danaei, G.1    Ding, E.L.2    Mozaffarian, D.3
  • 7
    • 77957690115 scopus 로고    scopus 로고
    • Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: Four-year results of the Look AHEAD trial
    • Look AHEAD Research Group
    • Wing RR; Look AHEAD Research Group. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med 2010;170:1566-75.
    • (2010) Arch Intern Med , vol.170 , pp. 1566-1575
    • Wing, R.R.1
  • 8
    • 0034185699 scopus 로고    scopus 로고
    • Overweight, obesity, and blood pressure: The effects of modest weight reduction
    • Mertens IL, van Gaal LF. Overweight, obesity, and blood pressure: The effects of modest weight reduction. Obes Res 2000;8:270-8.
    • (2000) Obes Res , vol.8 , pp. 270-278
    • Mertens, I.L.1    Van Gaal, L.F.2
  • 9
    • 77349106466 scopus 로고    scopus 로고
    • The surgical treatment of metabolic disease and morbid obesity
    • Fontana MA, Wohlgemuth SD. The surgical treatment of metabolic disease and morbid obesity. Gastroenterol Clin North Am 2010;39:125-33.
    • (2010) Gastroenterol Clin North Am , vol.39 , pp. 125-133
    • Fontana, M.A.1    Wohlgemuth, S.D.2
  • 10
    • 33646461265 scopus 로고    scopus 로고
    • The costs of nonsurgical and surgical weight loss interventions: Is an ounce of prevention really worth a pound of cure
    • Jensen C, Flum DR. The costs of nonsurgical and surgical weight loss interventions: is an ounce of prevention really worth a pound of cure Surg Obes Relat Dis 2005;1:353-7.
    • (2005) Surg Obes Relat Dis , vol.1 , pp. 353-357
    • Jensen, C.1    Flum, D.R.2
  • 11
    • 78049421954 scopus 로고    scopus 로고
    • Risk of suicide after long-term follow-up from bariatric surgery
    • Tindle HA, Omalu B, Courcoulas A, et al. Risk of suicide after long-term follow-up from bariatric surgery. Am J Med 2010;123:1036-42.
    • (2010) Am J Med , vol.123 , pp. 1036-1042
    • Tindle, H.A.1    Omalu, B.2    Courcoulas, A.3
  • 12
    • 84867773387 scopus 로고    scopus 로고
    • The FDA's assessment of two drugs for chronic weight management
    • Colman E, Golden J, Roberts M, et al. The FDA's assessment of two drugs for chronic weight management. N Engl J Med 2012;367:1577-9.
    • (2012) N Engl J Med , vol.367 , pp. 1577-1579
    • Colman, E.1    Golden, J.2    Roberts, M.3
  • 13
    • 77956658482 scopus 로고    scopus 로고
    • ACS chemical neuroscience molecule spotlight on lorcaserin
    • Hopkins CR. ACS chemical neuroscience molecule spotlight on lorcaserin. ACS Chem Neurosci 2010;1:718-19.
    • (2010) ACS Chem Neurosci , vol.1 , pp. 718-719
    • Hopkins, C.R.1
  • 14
    • 42449134961 scopus 로고    scopus 로고
    • Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: In vitro and in vivo pharmacological characterization
    • Thomsen WJ, Grottick AJ, Menzaghi F, et al. Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization. J Pharmacol Exp Ther 2008;325:577-87.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 577-587
    • Thomsen, W.J.1    Grottick, A.J.2    Menzaghi, F.3
  • 15
    • 38349114737 scopus 로고    scopus 로고
    • Discovery and structure-activity relationship of (1R)-8-chloro-2, 3, 4, 5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity
    • Smith BM, Smith JM, Tsai JH, et al. Discovery and structure-activity relationship of (1R)-8-chloro-2, 3, 4, 5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity. J Med Chem 2008;51:305-13.
    • (2008) J Med Chem , vol.51 , pp. 305-313
    • Smith, B.M.1    Smith, J.M.2    Tsai, J.H.3
  • 16
    • 79953023217 scopus 로고    scopus 로고
    • The use of serotonergic drugs to treat obesity-is there any hope
    • Bello NT and Liang N. The use of serotonergic drugs to treat obesity-is there any hope Drug Des Devel Ther 2011;5:95-109.
    • (2011) Drug des Devel Ther , vol.5 , pp. 95-109
    • Bello, N.T.1    Liang, N.2
  • 17
    • 84872370674 scopus 로고    scopus 로고
    • Zofingen, Switzerland: Arena Pharmaceuticals GmbH; June, (accessed 8 Sep 2013)
    • Belviq (lorcaserin hydrochloride) package insert. Zofingen, Switzerland: Arena Pharmaceuticals GmbH; June 2012. http://www. belviq. com/pdf/ Belviq-Prescribing-information. pdf (accessed 8 Sep 2013).
    • (2012) Belviq (Lorcaserin Hydrochloride) Package Insert
  • 18
    • 77952096280 scopus 로고    scopus 로고
    • Centers for Disease Control, (accessed 8 Sep 2013)
    • Prevalence of overweight, obesity, and extreme obesity among adults. Centers for Disease Control, 2011. http://www. cdc. gov/nchs/ data/hestat/obesity-adult-09-10/obesity-adult-09-10. htm (accessed 8 Sep 2013).
    • (2011) Prevalence of Overweight, Obesity, and Extreme Obesity among Adults
  • 19
    • 85006891490 scopus 로고    scopus 로고
    • (accessed 8 Sep 2013)
    • The FDA Lorcaserin Medical Review. http://www. Accessdata. fda. gov/drugsatfda-docs/nda/2012/022529Orig1s000MedR. pdf (accessed 8 Sep 2013).
    • The FDA Lorcaserin Medical Review
  • 20
    • 84884478505 scopus 로고    scopus 로고
    • Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials
    • Weissman NJ, Sanchez M, Koch GG, et al. Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials. Circ Cardiovasc Imaging 2013;6:560-7.
    • (2013) Circ Cardiovasc Imaging , vol.6 , pp. 560-567
    • Weissman, N.J.1    Sanchez, M.2    Koch, G.G.3
  • 21
    • 78649922972 scopus 로고    scopus 로고
    • Drug-induced valvulopathy: An update
    • Elangbam CS. Drug-induced valvulopathy: An update. Toxicol Pathol 2010;38:837-48.
    • (2010) Toxicol Pathol , vol.38 , pp. 837-848
    • Elangbam, C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.