Long-term risk of falls in an incident Parkinson’s disease cohort: the Norwegian ParkWest study

Journal of Neurology

Volumn 264, Issue 2, 2017, Pages 364-372

  Hiorth, Ylva Hivand ^a   Alves, Guido ^a   Larsen, Jan Petter ^b   Schulz, Jörn ^a,b   Tysnes, Ole Bjørn ^c,d   Pedersen, Kenn Freddy ^a  

^a STAVANGER UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF STAVANGER   (Norway)

^c UNIVERSITY OF BERGEN   (Norway)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cohort study; Epidemiology; Falls; Follow up study; Parkinson s disease; Risk factors

Indexed keywords

AGE; AGED; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEMENTIA; FALL RISK; FALL RISK ASSESSMENT; FEMALE; FOLLOW UP; GAIT DISORDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; UNIFIED PARKINSON DISEASE RATING SCALE; DISABILITY; DISEASE COURSE; FALLING; INCIDENCE; KAPLAN MEIER METHOD; NORWAY; PREVALENCE; QUESTIONNAIRE; RISK; STATISTICS AND NUMERICAL DATA; TIME FACTOR;

ACCIDENTAL FALLS; AGE FACTORS; AGED; DISABILITY EVALUATION; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; KAPLAN-MEIER ESTIMATE; MALE; NORWAY; PARKINSON DISEASE; PREVALENCE; PROSPECTIVE STUDIES; RISK; RISK FACTORS; SURVEYS AND QUESTIONNAIRES; TIME FACTORS;

EID: 85006751448     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-016-8365-z     Document Type: Article

References (35)

1. Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ (2014) Bone health in Parkinson’s disease: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 85(10):1159–1166. doi:10.1136/jnnp-2013-307307
2. Hiorth YH, Larsen JP, Lode K, Tysnes OB, Godfrey A, Lord S, Rochester L, Pedersen KF (2016) Impact of falls on physical activity in people with Parkinson’s Disease. J Parkinson’s Dis 6(1):175–182. doi:10.3233/JPD-150640
3. Schrag A, Hovris A, Morley D, Quinn N, Jahanshahi M (2006) Caregiver-burden in Parkinson’s disease is closely associated with psychiatric symptoms, falls, and disability. Parkinsonism Relat Disord 12(1):35–41. doi:10.1016/j.parkreldis.2005.06.011
4. Rahman S, Griffin HJ, Quinn NP, Jahanshahi M (2008) Quality of life in Parkinson’s disease: the relative importance of the symptoms. Mov Disord 23(10):1428–1434. doi:10.1002/mds.21667
5. Bach JP, Ziegler U, Deuschl G, Dodel R, Doblhammer-Reiter G (2011) Projected numbers of people with movement disorders in the years 2030 and 2050. Mov Disord 26(12):2286–2290. doi:10.1002/mds.23878
6. Allen NE, Schwarzel AK, Canning CG (2013) Recurrent falls in Parkinson’s disease: a systematic review. Parkinsons Dis 2013:906274. doi:10.1155/2013/906274
7. Allan LM, Ballard CG, Rowan EN, Kenny RA (2009) Incidence and prediction of falls in dementia: a prospective study in older people. PLoS One 4(5):e5521. doi:10.1371/journal.pone.0005521
8. Pickering RM, Grimbergen YA, Rigney U, Ashburn A, Mazibrada G, Wood B, Gray P, Kerr G, Bloem BR (2007) A meta-analysis of six prospective studies of falling in Parkinson’s disease. Mov Disord 22(13):1892–1900. doi:10.1002/mds.21598
9. Paul SS, Canning CG, Sherrington C, Lord SR, Close JC, Fung VS (2013) Three simple clinical tests to accurately predict falls in people with Parkinson’s disease. Mov Disord 28(5):655–662. doi:10.1002/mds.25404
10. Alves G, Muller B, Herlofson K, HogenEsch I, Telstad W, Aarsland D, Tysnes OB, Larsen JP, Norwegian ParkWest Study g (2009) Incidence of Parkinson’s disease in Norway: the Norwegian ParkWest study. J Neurol Neurosurg Psychiatry 80(8):851–857. doi:10.1136/jnnp.2008.168211
11. Aarsland D, Bronnick K, Larsen JP, Tysnes OB, Alves G (2009) Cognitive impairment in incident, untreated Parkinson disease: the Norwegian ParkWest study. Neurology 72(13):1121–1126. doi:10.1212/01.wnl.0000338632.00552.cb
12. Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55(3):181–184
13. Fahn S, Elton R, Program Members UPDRS (1987) Unified Parkinson’s disease rating scale.In:Fahn S, Marsden CD, Goldstein M, Calne DB (eds) Recent developments in Parkinson’s disease, vol 2. Macmillan Healthcare Information, Florham Park
14. Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17(5):427–442
15. Jankovic J, McDermott M, Carter J, Gauthier S, Goetz C, Golbe L, Huber S, Koller W, Olanow C, Shoulson I et al (1990) Variable expression of Parkinson’s disease: a base-line analysis of the DATATOP cohort. The Parkinson Study Group. Neurology 40(10):1529–1534
16. Giladi N, Shabtai H, Simon ES, Biran S, Tal J, Korczyn AD (2000) Construction of freezing of gait questionnaire for patients with Parkinsonism. Parkinsonism Relat Disord 6(3):165–170
17. Folstein MF, Folstein SE, McHugh PR (1975) “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189–198
18. Emre M, Aarsland D, Brown R, Burn DJ, Duyckaerts C, Mizuno Y, Broe GA, Cummings J, Dickson DW, Gauthier S, Goldman J, Goetz C, Korczyn A, Lees A, Levy R, Litvan I, McKeith I, Olanow W, Poewe W, Quinn N, Sampaio C, Tolosa E, Dubois B (2007) Clinical diagnostic criteria for dementia associated with Parkinson’s disease. Mov Disord 22(12):1689–1707. doi:10.1002/mds.21507 (quiz 1837)
19. Montgomery SA, Asberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatr 134:382–389
20. Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, Clarke CE (2010) Systematic review of levodopa dose equivalency reporting in Parkinson’s disease. Mov Disord 25(15):2649–2653. doi:10.1002/mds.23429
21. Lamb SE, Jorstad-Stein EC, Hauer K, Becker C, Prevention of Falls Network E, Outcomes Consensus G (2005) Development of a common outcome data set for fall injury prevention trials: the Prevention of Falls Network Europe consensus. J Am Geriatr Soc 53(9):1618–1622. doi:10.1111/j.1532-5415.2005.53455.x
22. Von Hippel P (2007) Regression with missing Ys: an improved strategy for analyzing multiply imputed data. Sociol Methodol 37:83–117
23. Mactier K, Lord S, Godfrey A, Burn D, Rochester L (2015) The relationship between real world ambulatory activity and falls in incident Parkinson’s disease: influence of classification scheme. Parkinsonism Relat Disord 21(3):236–242. doi:10.1016/j.parkreldis.2014.12.014
24. Lord S, Galna B, Yarnall AJ, Coleman S, Burn D, Rochester L (2016) Predicting first fall in newly diagnosed Parkinson’s disease: insights from a fall-naive cohort. Mov Disord. doi:10.1002/mds.26742
25. Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G (2015) MDS clinical diagnostic criteria for Parkinson’s disease. Mov Disord 30(12):1591–1601. doi:10.1002/mds.26424
26. Hiorth YH, Larsen JP, Lode K, Pedersen KF (2014) Natural history of falls in a population-based cohort of patients with Parkinson’s disease: an 8-year prospective study. Parkinsonism Relat Disord 20(10):1059–1064. doi:10.1016/j.parkreldis.2014.06.023
27. Hely MA, Morris JG, Reid WG, Trafficante R (2005) Sydney Multicenter Study of Parkinson’s disease: non-l-dopa-responsive problems dominate at 15 years. Mov Disord 20(2):190–199. doi:10.1002/mds.20324
28. Auyeung M, Tsoi TH, Mok V, Cheung CM, Lee CN, Li R, Yeung E (2012) Ten year survival and outcomes in a prospective cohort of new onset Chinese Parkinson’s disease patients. J Neurol Neurosurg Psychiatry 83(6):607–611. doi:10.1136/jnnp-2011-301590
29. Lord SR (2007) Falls in older people: risk factors and strategies for prevention, 2nd edn. Cambridge University Press, Cambridge
30. Almeida LR, Valenca GT, Negreiros NN, Pinto EB, Oliveira-Filho J (2014) Recurrent falls in people with parkinson’s disease without cognitive impairment: focusing on modifiable risk factors. Parkinson’s Dis 2014:432924
31. Kerr GK, Worringham CJ, Cole MH, Lacherez PF, Wood JM, Silburn PA (2010) Predictors of future falls in Parkinson disease. Neurology 75(2):116–124. doi:10.1212/WNL.0b013e3181e7b688
32. Curtze C, Nutt JG, Carlson-Kuhta P, Mancini M, Horak FB (2015) Levodopa is a double-edged sword for balance and gait in people with Parkinson’s disease. Mov Disord 30(10):1361–1370. doi:10.1002/mds.26269
33. Bohnen NI, Muller ML, Koeppe RA, Studenski SA, Kilbourn MA, Frey KA, Albin RL (2009) History of falls in Parkinson disease is associated with reduced cholinergic activity. Neurology 73(20):1670–1676. doi:10.1212/WNL.0b013e3181c1ded6
34. Rochester L, Yarnall AJ, Baker MR, David RV, Lord S, Galna B, Burn DJ (2012) Cholinergic dysfunction contributes to gait disturbance in early Parkinson’s disease. Brain 135(Pt 9):2779–2788. doi:10.1093/brain/aws207
35. Henderson EJ, Lord SR, Brodie MA, Gaunt DM, Lawrence AD, Close JC, Whone AL, Ben-Shlomo Y (2016) Rivastigmine for gait stability in patients with Parkinson’s disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol 15(3):249–258. doi:10.1016/S1474-4422(15)00389-0