Model averaging for treatment effect estimation in subgroups

Pharmaceutical Statistics

Volumn 16, Issue 2, 2017, Pages 133-142

  Bornkamp, Björn ^a   Ohlssen, David ^a   Magnusson, Baldur P ^a   Schmidli, Heinz ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Bayesian inference; exploratory study; proof of concept trial; shrinkage; subgroup analysis

Indexed keywords

AVERAGING; CLINICAL TRIAL; HUMAN; MODEL; MOTIVATION; UNCERTAINTY; BAYES THEOREM; CLINICAL TRIAL (TOPIC); COMPUTER SIMULATION; METHODOLOGY; PROCEDURES; SELECTION BIAS; STATISTICAL ANALYSIS; STATISTICAL MODEL;

BAYES THEOREM; CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; HUMANS; MODELS, STATISTICAL; RESEARCH DESIGN; SELECTION BIAS; UNCERTAINTY;

EID: 85006707419     PISSN: 15391604     EISSN: 15391612     Source Type: Journal    
DOI: 10.1002/pst.1796     Document Type: Article

References (20)

1. J. Woodcock,Clin. Pharmacol. Ther. 2007, 81, 164.
2. S. Ruberg, L. Chen, Y. Wang, Clinical Trials. 2010, 7, 574.
3. I. Lipkovich, A. Dmitrienko, J. Denne, G. Enas, Stat. Med. 2011, 30(21), 2601.
4. J. C. Foster, J. M. G. Taylor, S. J. Ruberg, Stat. Med. 2011, 30(24), 2867.
5. J. O. Berger, X. Wang, L. Shen, J. Biopharm. Stat. 2014, 24, 110.
6. S. J. Ruberg, L. Shen, Stat. Biopharm. Res. 2015, 7, 214.
7. T. R. Fleming, Ann. Intern. Med. 2010, 153(6), 400.
8. L. Sun, S. B. Bull, Genet. Epidemiol. 2005, 28, 352.
9. G. K. Rosenkranz, Comput. Stat. Data Anal. 2014, 69, 220.
10. G. K. Rosenkranz, Biom. J. 2016, 58, 1217.
11. D. O. Dixon, R. Simon, Biometrics. 1991, 47, 871.
12. H. E. Jones, D. I. Ohlssen, B. Neuenschwander, A. Racine, M. Branson, Clinical Trials. 2011, 8, 129.
13. B. Neuenschwander, S. Wandel, S. Roychoudhury, S. Bailey, Pharm. Stat. 2015, 15, 123.
14. R. Varadhan, S.-J. Wang, Biom. J. 2016, 58, 133.
15. A. O'Hagan, J. Forster, Kendall's Advanced Theory of Statistics, volume 2b: Bayesian Inference, 2nd ed., Arnold, London 2004.
16. M. Plummer. JAGS Version 3.4.0 user manual 2014. http://mcmc-jags.sourceforge.net. (accessed: November 28, 2016)
17. A. E. Raftery, Sociol. Methodol. 1995, 25, 111.
18. D. Draper, J. R. Stat. Soc. Series B Stat. Methodol. 1995, 57, 45.
19. A. Liaw, M. Wiener, R News. 2002, 2(3), 18.
20. B. Efron, J. Am. Stat. Assoc. 2014, 109, 991.