Self-aggregates of Highly Hydrophobic Phospholipid Polymers in Aqueous Solution

Journal of Oleo Science

Volumn 55, Issue 9, 2006, Pages 465-471

  Yamamoto, Nobuyuki ^a,b   Irie, Hirofumi ^a   Sakamoto, Nobuyuki ^a   Shuto, Kenshiro ^a   Yamagishi, Tada Aki ^b   Nakamoto, Yoshiaki ^b  

^a NOF Corporation   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

MPC; nano; phosphorylcholine; self aggregate; solubilization

Indexed keywords

EID: 85006587763     PISSN: 13458957     EISSN: 13473352     Source Type: Journal    
DOI: 10.5650/jos.55.465     Document Type: Article

References (21)

1. Y. MIZUSHIMA, Lipid Microspheres as Novel Drug Carriers, Drugs Exp. Clin. Res., Vol. 11, 595-600 (1985).
2. K. ISHIHARA, R. ARAGAKI, T. UEDA, A. WATANABE and N. NAKABAYASHI, Reduced Thrombogenicity of Polymers Having Phospholipid Polar Groups, J. Biomed. Mater. Res., Vol. 24, 1069-1077 (1990).
3. K. ISHIHARA, N.P. ZIATS, B.P. TIERNEY, N. NAKABAYASHI and J.M. ANDERSON, Protein Adsorption from Human Plasma is Reduced on Phospholipid Polymer, J. Biomed. Mater. Res., Vol. 25, 1397-1407 (1991).
4. K. ISHIHARA, H. OSHIDA, T. UEDA, Y. ENDO, A. WATANABE and N. NAKABAYASHI, Hemocompatibility of Human Whole Blood on Polymers with a Phospholipid Polar Group and its Mechanism, J. Biomed. Mater. Res., Vol. 26, 1543-1552 (1992).
5. Y. IWASAKI, A. MIKAMI, K. KURITA, N. YUI, K. ISHIHARA and N. NAKABAYASHI, Reduction of Surface-induced Platelet Activation on Phospholipid Polymer, J. Biomed. Mater. Res., Vol. 36, 508-515 (1997).
6. Y. KADOMA, N. NAKABAYASHI, E. MASUHARA and J. YAMAUCHI, Synthesis and Hemolysis Test of the Polymer Containing Phosphorylcholine Groups, Kobunshi Ronbunshu, Vol. 35, 423-427 (1978).
7. K. ISHIHARA, Y. IWASAKI and N. NAKABAYASHI, Polymeric Lipid Nanosphere Consisting of Water-soluble Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate), Polym J., Vol. 31, 1231-1236 (1999).
8. T. KONNO, J. WATANABE and K. ISHIHARA, Enhanced Solubility of Paclitaxel Using Water-soluble and Biocompatible 2-Methacryloyloxyethyl Phosphorylcholine Polymers, J. Biomed. Mater. Res. A, Vol. 65, 210-215 (2003).
9. N. YAMAMOTO, H. FUKUI, N. SAKAMOTO, K. SHUTO and K. SUZUKI, Japan Patent Pending, No.2004-196868.
10. N. YAMAMOTO and K. SHUTO, Aqueous Nanodispersion of Water-insoluble Phospholipid Polymers, Preprints of the 8th SPSJ International Polymer Conferance (IPC2005), 425 (2005).
11. T. UEDA, H. OSHIDA, K. KURITA, K. ISHIHARA and N. NAKABAYASHI, Preparation of 2-Methacryloyloxyethyl Phosphorylcholine Copolymers with Alkyl Methacrylates and Their Blood Compatibility, Polym. J., Vol. 24, 1259-1269 (1992).
12. N. TANI, S. KINOSHITA, Y. OKAMOTO, M. KOTANI, H. ITAGAKI, N. MURAKAMI, S. SUGIURA, M. USAMI, K. KATO, H. KOJIMA, T. OHNO, K. SAIJO, M. KATO, M. HAYASHI and Y. OHNO, Interlaboratory Validation of the In Vitro Eye Irritation Tests for Cosmetic Ingredients. (8) Evaluation of Cytotoxicity Tests on SIRC Cells, Toxicology in Vitro, Vol. 13, 175-187 (1999).
13. S. BATZRI and E.D. KORN, Single Bilayer Liposomes Prepared without Sonication, Biochim Biophys Acta., Vol. 298, 1015-1019 (1973).
14. J.M. KREMER, M.W. ESKER, C. PATHMAMANOHARAN and P.H. WIERSEMA, Vesicles of Variable Diameter Prepared by Modified Injection Method, Biochemistry, Vol. 16, 3932-3935 (1977).
15. M. PONS, M. FORADADA and J. ESTELRICH, Liposomes Obtained by the Ethanol Injection Method, Int. J. Pharm., Vol. 95, 51-56 (1993).
16. Y. MAITANI, H. SOEDA, J.P. WANG and K. TAKAYAMA, Modified Ethanol Injection Method for Liposomes Containing b-Sitosterol b-D-Glucoside, J. Liposome Research, Vol. 11, 115-125 (2001).
17. D.D. LASIC, The Spontaneous Formation of Unilamellar Vesicles, J. Colloid interface Sci., Vol. 124, 428-435 (1988).
18. H. HAUSER, N. GAINS, H.J. EIBL, M. MULLER and E. WEHRLI, Spontaneous Vesiculation of Aqueous Lipid Dispersions, Biochemistry, Vol. 25, 2126-2134 (1986).
19. F. Ishii, A. TAKAMURA and Y. ISHIGAMI, Procedure for Preparation of Lipid Vesicles (Liposomes) Using the Coacerva-tion (Phase Separation) Technique, Langmuir, Vol. 11, 483-486 (1995).
20. B. FREI, M.C. KIM and B.N. AMES, Ubiquinol-10 is an Effective Lipid-Soluble Antioxidant at Physiological Concentrations, Proc. Natl. Acad. Sci. USA, Vol. 87, 4879-4883 (1990).
21. S.R. BERGMANN, T.B. FERGUSON Jr. and B.E. SOBEL, Effects of Amphiphiles on Erythrocytes, Coronary Arteries, and Perfused Hearts, Am. J. Physiol., Vol. 240, H229-H237 (1981).