Prognostic value of cardiac troponin T and sex in patients undergoing elective percutaneous coronary intervention

Journal of the American Heart Association

Volumn 5, Issue 12, 2016, Pages

  Harada, Yukinori ^a   Michel, Jonathan ^a   Koenig, Wolfgang ^a   Rheude, Tobias ^a   Colleran, Roisin ^a   Giacoppo, Daniele ^a   Kastrati, Adnan ^a   Byrne, Robert A ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Percutaneous coronary intervention; Sex; Stable coronary artery disease; Troponin T

Indexed keywords

ACETYLSALICYLIC ACID; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TROPONIN T;

AGED; ARTICLE; CARDIOVASCULAR MORTALITY; CENTRIFUGATION; CONTROLLED STUDY; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DYSLIPIDEMIA; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE ANALYSIS; SEX DIFFERENCE; BLOOD; CAUSE OF DEATH; DIAGNOSTIC IMAGING; ELECTIVE SURGERY; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CAUSE OF DEATH; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; ELECTIVE SURGICAL PROCEDURES; FEMALE; HUMANS; MALE; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PERCUTANEOUS CORONARY INTERVENTION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SEX FACTORS; TROPONIN T;

EID: 85006401170     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.116.004464     Document Type: Article

References (24)

1. Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S, Baumgartner H, Gaemperli O, Achenbach S, Agewall S, Badimon L, Baigent C, Bueno H, Bugiardini R, Carerj S, Casselman F, Cuisset T, Erol Ć, Fitzsimons D, Halle M, Hamm C, Hildick-Smith D, Huber K, Iliodromitis E, James S, Lewis BS, Lip GY, Piepoli MF, Richter D, Rosemann T, Sechtem U, Steg PG, Vrints C, Luis Zamorano J. 2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J. 2016;37:267-315.
2. Sze J, Mooney J, Barzi F, Hillis GS, Chow CK. Cardiac troponin and its relationship to cardiovascular outcomes in community populations-a systematic review and meta-analysis. Heart Lung Circ. 2016;25:217-228.
3. Oemrawsingh RM, Cheng JM, García-García HM, Kardys I, van Schaik RH, Regar E, van Geuns RJ, Serruys PW, Boersma E, Akkerhuis KM. High-sensitivity troponin T in relation to coronary plaque characteristics in patients with stable coronary artery disease; results of the ATHEROREMO-IVUS study. Atherosclerosis. 2016;247:135-141.
4. Caselli C, Prontera C, Liga R, De Graaf MA, Gaemperli O, Lorenzoni V, Ragusa R, Marinelli M, Del Ry S, Rovai D, Giannessi D, Aguade-Bruix S, Clemente A, Bax JJ, Lombardi M, Sicari R, Zamorano J, Scholte AJ, Kaufmann PA, Knuuti J, Underwood SR, Clerico A, Neglia D. Effect of coronary atherosclerosis and myocardial ischemia on plasma levels of high-sensitivity troponin T and NTproBNP in patients with stable angina. Arterioscler Thromb Vasc Biol. 2016;36:757-764.
5. Beatty AL, Ku IA, Christenson RH, DeFilippi CR, Schiller NB, Whooley MA. Highsensitivity cardiac troponin T levels and secondary events in outpatients with coronary heart disease from the Heart and Soul Study. JAMA Intern Med. 2013;173:763-769.
6. Omland T, de Lemos JA, Sabatine MS, Christophi CA, Rice MM, Jablonski KA, Tjora S, Domanski MJ, Gersh BJ, Rouleau JL, Pfeffer MA, Braunwald E. A sensitive cardiac troponin T assay in stable coronary artery disease. N Engl J Med. 2009;361:2538-2547.
7. Koenig W, Breitling LP, Hahmann H, Wüsten B, Brenner H, Rothenbacher D. Cardiac troponin T measured by a high-sensitivity assay predicts recurrent cardiovascular events in stable coronary heart disease patients with 8-year follow-up. Clin Chem. 2012;58:1215-1224.
8. Lyngbæk S, Winkel P, Gøtze JP, Kastrup J, Gluud C, Kolmos HJ, Kjøller E, Jensen GB, Hansen JF, Hildebrandt P, Hilden J. Risk stratification in stable coronary artery disease is possible at cardiac troponin levels below conventional detection and is improved by use of N-terminal pro-B-type natriuretic peptide. Eur J Prev Cardiol. 2014;21:1275-1284.
9. Everett BM, Brooks MM, Vlachos HE, Chaitman BR, Frye RL, Bhatt DL. Troponin and cardiac events in stable ischemic heart disease and diabetes. N Engl J Med. 2015;373:610-620.
10. Lepojärvi ES, Piira OP, Kiviniemi AM, Miettinen JA, Kenttä T, Ukkola O, Tulppo MP, Huikuri HV, Junttila MJ. Usefulness of highly sensitive troponin as a predictor of short-term outcome in patients with diabetes mellitus and stable coronary artery disease (from the ARTEMIS Study). Am J Cardiol. 2016;117:515-521.
11. Omland T, Pfeffer MA, Solomon SD, de Lemos JA, Røsjø H, Saltyte Benth J, Maggioni A, Domanski MJ, Rouleau JL, Sabatine MS, Braunwald E. Prognostic value of cardiac troponin I measured with a highly sensitive assay in patients with stable coronary artery disease. J Am Coll Cardiol. 2013;61:1240-1249.
12. Lupi A, Rognoni A, Lazzero M, Rolla R, Pergolini P, Bellomo G, Rossi L, Sante Bongo A, Jaffe AS. Below normal pre-procedural cardiac troponin I levels are associated with an adverse prognosis after percutaneous coronary interventions. EuroIntervention. 2016;11:1380-1388.
13. Carda R, Acena Á, Pello A, Cristóbal C, Tarín N, Huelmos A, Alonso J, Asensio D, Lorenzo Ó, Martín-Ventura JL, Blanco-Colio L, Farré J, López Bescós L, Egido J, Tunón J. The prognostic value of high-sensitive troponin I in stable coronary artery disease depends on age and other clinical variables. Cardiology. 2015;132:1-8.
14. Omland T, de Lemos JA, Holmen OL, Dalen H, Benth JS, Nygård S, Hveem K, Røsjø H. Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: the HUNT study. Clin Chem. 2015;61:646-656.
15. Dallmeier D, Denkinger M, Peter R, Rapp K, Jaffe AS, Koenig W, Rothenbacher D. Sex-specific associations of established and emerging cardiac biomarkers with all-cause mortality in older adults: the ActiFE study. Clin Chem. 2015;61:389-399.
16. Eggers KM, Johnston N, James S, Lindahl B, Venge P. Cardiac troponin I levels in patients with non-ST-elevation acute coronary syndrome-the importance of gender. Am Heart J. 2014;168:317-324.e1.
17. van Buuren S, Groothuis-Oudshoorn K. Mice: Multivariate imputation by chained equations in R. J Stat Softw. 2011;45:1-67.
18. White HD. Pathobiology of troponin elevations: do elevations occur with myocardial ischemia as well as necrosis? J Am Coll Cardiol. 2011;57:2406-2408.
19. Turer AT, Addo TA, Martin JL, Sabatine MS, Lewis GD, Gerszten RE, Keeley EC, Cigarroa JE, Lange RA, Hillis LD, de Lemos JA. Myocardial ischemia induced by rapid atrial pacing causes troponin T release detectable by a highly sensitive assay: insights from a coronary sinus sampling study. J Am Coll Cardiol. 2011;57:2398-2405.
20. Miller WL, Garratt KN, Burritt MF, Lennon RJ, Reeder GS, Jaffe AS. Baseline troponin level: key to understanding the importance of post-PCI troponin elevations. Eur Heart J. 2006;27:1061-1069.
21. Barbier CE, Themudo R, Bjerner T, Johansson L, Lindahl B, Venge P, Lind L, Ahlström H. Cardiac troponin I associated with the development of unrecognized myocardial infarctions detected with MRI. Clin Chem. 2014;60:1327-1335.
22. Zanchin T, Räber L, Koskinas KC, Piccolo R, Jüni P, Pilgrim T, Stortecky S, Khattab AA, Wenaweser P, Bloechlinger S, Moschovitis A, Frenk A, Moro C, Meier B, Fiedler GM, Heg D, Windecker S. Preprocedural high-sensitivity cardiac troponin T and clinical outcomes in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention. Circ Cardiovasc Interv. 2016;9:e003202.
23. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, Hashim I, Berry JD, Das SR, Morrow DA, McGuire DK. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA. 2010;304:2503-2512.
24. Eggers KM, Johnston N, Lind L, Venge P, Lindahl B. Cardiac troponin I levels in an elderly population from the community-the implications of sex. Clin Biochem. 2015;48:751-756.