-
2
-
-
0031059994
-
Detection of adeno-associated virus type 2 sequences in the human genital tract
-
Friedman-Einat M, Grossman Z, Mileguir F, et al. Detection of adeno-associated virus type 2 sequences in the human genital tract. J Clin Microbiol 1997;35:71-78.
-
(1997)
J Clin Microbiol
, vol.35
, pp. 71-78
-
-
Friedman-Einat, M.1
Grossman, Z.2
Mileguir, F.3
-
3
-
-
2642512201
-
Clades of adeno-associated viruses are widely disseminated in human tissues
-
Gao G, Vandenberghe LH, Alvira MR, et al. Clades of adeno-associated viruses are widely disseminated in human tissues. J Virol 2004;78:6381-6388.
-
(2004)
J Virol
, vol.78
, pp. 6381-6388
-
-
Gao, G.1
Vandenberghe, L.H.2
Alvira, M.R.3
-
4
-
-
84863419418
-
Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs
-
Shin JH, Yue Y, Smith B, et al. Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs. Hum Gene Ther 2012;23:287-294.
-
(2012)
Hum Gene Ther
, vol.23
, pp. 287-294
-
-
Shin, J.H.1
Yue, Y.2
Smith, B.3
-
5
-
-
84856958590
-
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models
-
Rapti K, Louis-Jeune V, Kohlbrenner E, et al. Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. Mol Ther 2012;20:73-83.
-
(2012)
Mol Ther
, vol.20
, pp. 73-83
-
-
Rapti, K.1
Louis-Jeune, V.2
Kohlbrenner, E.3
-
6
-
-
80052496589
-
Impact of preexisting immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors
-
Wang L, Calcedo R, Bell P, et al. Impact of preexisting immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors. Hum Gene Ther 2011;22:1389-1401.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 1389-1401
-
-
Wang, L.1
Calcedo, R.2
Bell, P.3
-
7
-
-
77954976233
-
Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: Implications for gene therapy using AAV vectors
-
Boutin S, Monteilhet V, Veron P, et al. Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: Implications for gene therapy using AAV vectors. Hum Gene Ther 2010;21:704-712.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 704-712
-
-
Boutin, S.1
Monteilhet, V.2
Veron, P.3
-
8
-
-
84964758548
-
Neutralizing antibodies against adeno-associated viral capsids in patients with mut methylmalonic acidemia
-
Harrington EA, Sloan JL, Manoli I, et al. Neutralizing antibodies against adeno-associated viral capsids in patients with mut methylmalonic acidemia. Hum Gene Ther 2016;27:345-353.
-
(2016)
Hum Gene Ther
, vol.27
, pp. 345-353
-
-
Harrington, E.A.1
Sloan, J.L.2
Manoli, I.3
-
9
-
-
84960101848
-
Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure
-
Greenberg B, Butler J, Felker GM, et al. Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure. Gene Ther 2016;23: 313-319.
-
(2016)
Gene Ther
, vol.23
, pp. 313-319
-
-
Greenberg, B.1
Butler, J.2
Felker, G.M.3
-
10
-
-
85050580206
-
Prevalence of neutralizing antibodies against liver-tropic adenoassociated virus serotype vectors in 100 healthy Chinese and its potential relation to body constitutions
-
Ling C, Wang Y, Feng YL, et al. Prevalence of neutralizing antibodies against liver-tropic adenoassociated virus serotype vectors in 100 healthy Chinese and its potential relation to body constitutions. J Integr Med 2015;13:341-346.
-
(2015)
J Integr Med
, vol.13
, pp. 341-346
-
-
Ling, C.1
Wang, Y.2
Feng, Y.L.3
-
11
-
-
84932605736
-
Preexisting neutralizing antibodies to adeno-associated virus capsids in large animals other than monkeys may confound in vivo gene therapy studies
-
Calcedo R, Franco J, Qin Q, et al. Preexisting neutralizing antibodies to adeno-associated virus capsids in large animals other than monkeys may confound in vivo gene therapy studies. Hum Gene Ther Methods 2015;26:103-105.
-
(2015)
Hum Gene Ther Methods
, vol.26
, pp. 103-105
-
-
Calcedo, R.1
Franco, J.2
Qin, Q.3
-
12
-
-
58849086758
-
Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses
-
Calcedo R, Vandenberghe LH, Gao G, et al. Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses. J Infect Dis 2009;199: 381-390.
-
(2009)
J Infect Dis
, vol.199
, pp. 381-390
-
-
Calcedo, R.1
Vandenberghe, L.H.2
Gao, G.3
-
13
-
-
80052497157
-
Adenoassociated virus antibody profiles in newborns, children, and adolescents
-
Calcedo R, Morizono H, Wang L, et al. Adenoassociated virus antibody profiles in newborns, children, and adolescents. Clin Vaccine Immunol 2011;18:1586-1588.
-
(2011)
Clin Vaccine Immunol
, vol.18
, pp. 1586-1588
-
-
Calcedo, R.1
Morizono, H.2
Wang, L.3
-
14
-
-
0037947557
-
Adenoassociated viruses undergo substantial evolution in primates during natural infections
-
Gao G, Alvira MR, Somanathan S, et al. Adenoassociated viruses undergo substantial evolution in primates during natural infections. Proc Natl Acad Sci U S A 2003;100:6081-6086.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6081-6086
-
-
Gao, G.1
Alvira, M.R.2
Somanathan, S.3
-
15
-
-
84922399417
-
AAVrh. 10 immunogenicity in mice and humans. Relevance of antibody cross-reactivity in human gene therapy
-
Thwaite R, Pages G, Chillon M, et al. AAVrh. 10 immunogenicity in mice and humans. Relevance of antibody cross-reactivity in human gene therapy. Gene Ther 2015;22:196-201.
-
(2015)
Gene Ther
, vol.22
, pp. 196-201
-
-
Thwaite, R.1
Pages, G.2
Chillon, M.3
-
16
-
-
84905911697
-
Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: Implications for gene therapy using AAV vectors
-
Liu Q, Huang W, Zhang H, et al. Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: Implications for gene therapy using AAV vectors. Gene Ther 2014;21:732-738.
-
(2014)
Gene Ther
, vol.21
, pp. 732-738
-
-
Liu, Q.1
Huang, W.2
Zhang, H.3
-
17
-
-
80155145248
-
Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing alpha1-antitrypsin: Interim results
-
Flotte TR, Trapnell BC, Humphries M, et al. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing alpha1-antitrypsin: Interim results. Hum Gene Ther 2011;22:1239-1247.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 1239-1247
-
-
Flotte, T.R.1
Trapnell, B.C.2
Humphries, M.3
-
18
-
-
70349481529
-
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy
-
Brantly ML, Chulay JD, Wang L, et al. Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy. Proc Natl Acad Sci U S A 2009;106: 16363-16368.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16363-16368
-
-
Brantly, M.L.1
Chulay, J.D.2
Wang, L.3
-
19
-
-
84855161388
-
Adenovirus-associated virus vector-mediated gene transfer in hemophilia B
-
Nathwani AC, Tuddenham EG, Rangarajan S, et al. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 2011;365: 2357-2365.
-
(2011)
N Engl J Med
, vol.365
, pp. 2357-2365
-
-
Nathwani, A.C.1
Tuddenham, E.G.2
Rangarajan, S.3
-
20
-
-
84911383748
-
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
-
Nathwani AC, Reiss UM, Tuddenham EG, et al. Long-term safety and efficacy of factor IX gene therapy in hemophilia B. N Engl J Med 2014;371: 1994-2004.
-
(2014)
N Engl J Med
, vol.371
, pp. 1994-2004
-
-
Nathwani, A.C.1
Reiss, U.M.2
Tuddenham, E.G.3
-
21
-
-
84923197177
-
Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: Preclinical evaluation supporting an ongoing adeno-associated virus clinical trial
-
Monahan PE, Sun J, Gui T, et al. Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: Preclinical evaluation supporting an ongoing adeno-associated virus clinical trial. Hum Gene Ther 2015; 26:69-81.
-
(2015)
Hum Gene Ther
, vol.26
, pp. 69-81
-
-
Monahan, P.E.1
Sun, J.2
Gui, T.3
-
22
-
-
84924976964
-
Prevalence of anti-adeno-associated virus serotype 8 neutralizing antibodies and arylsulfatase B cross-reactive immunologic material in mucopolysaccharidosis VI patient candidates for a gene therapy trial
-
Ferla R, Claudiani P, Savarese M, et al. Prevalence of anti-adeno-associated virus serotype 8 neutralizing antibodies and arylsulfatase B cross-reactive immunologic material in mucopolysaccharidosis VI patient candidates for a gene therapy trial. Hum Gene Ther 2015;26:145-152.
-
(2015)
Hum Gene Ther
, vol.26
, pp. 145-152
-
-
Ferla, R.1
Claudiani, P.2
Savarese, M.3
-
23
-
-
77958104835
-
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale
-
Lock M, Alvira M, Vandenberghe LH, et al. Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale. Hum Gene Ther 2010;21:1259-1271.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 1259-1271
-
-
Lock, M.1
Alvira, M.2
Vandenberghe, L.H.3
-
24
-
-
70049118306
-
Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates
-
Roy S, Vandenberghe LH, Kryazhimskiy S, et al. Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates. PLoS Pathogens 2009;5: e1000503.
-
(2009)
PLoS Pathogens
, vol.5
, pp. e1000503
-
-
Roy, S.1
Vandenberghe, L.H.2
Kryazhimskiy, S.3
-
25
-
-
80053611414
-
Adenoviruses in lymphocytes of the human gastrointestinal tract
-
Roy S, Calcedo R, Medina-Jaszek A, et al. Adenoviruses in lymphocytes of the human gastrointestinal tract. PLoS One 2011;6:e24859.
-
(2011)
PLoS One
, vol.6
, pp. e24859
-
-
Roy, S.1
Calcedo, R.2
Medina-Jaszek, A.3
-
26
-
-
62749200441
-
Host immune responses to chronic adenovirus infections in human and nonhuman primates
-
Calcedo R, Vandenberghe LH, Roy S, et al. Host immune responses to chronic adenovirus infections in human and nonhuman primates. J Virol 2009;83:2623-2631.
-
(2009)
J Virol
, vol.83
, pp. 2623-2631
-
-
Calcedo, R.1
Vandenberghe, L.H.2
Roy, S.3
|