Microarray-based component-resolved diagnosis of latex allergy: isolated IgE-mediated sensitization to latexprofilin Hev b8 may act as confounder

Clinical and Translational Allergy

Volumn 3, Issue 1, 2013, Pages 1-7

  Schuler, Sarah ^a   Ferrari, Giovanni ^b   Schmid Grendelmeier, Peter ^a   Harr, Thomas ^a,c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b Servizio di allergologia e immunologia clinica   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Carbohydrate cross reactive determinants; Component resolved diagnosis (CRD); Hev b 8; Latex; Profilin

Indexed keywords

HEVEIN; HEVEIN B8; IMMUNOGLOBULIN E; LATEX; PROFILIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALLERGY RAPID TEST; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CROSS ALLERGY; DIAGNOSTIC TEST; FEMALE; HUMAN; IMMUNOASSAY; LATEX ALLERGY; MALE; PRICK TEST; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SENSITIZATION; SEROLOGY; SYMPTOM;

EID: 85006096862     PISSN: None     EISSN: 20457022     Source Type: Journal    
DOI: 10.1186/2045-7022-3-11     Document Type: Article

References (23)

1. Wagner S, Breiteneder H: Hevea brasiliensis latex allergens: current panel and clinical relevance. Int Arch Allergy Immunol. 2005, 136 (1): 90-97. 10.1159/000082938.
2. Kurup VP, Sussman GL, Yeang HY, Elms N, Breiteneder H, Arif SA, Kelly KJ, Bansal NK, Fink JN: Specific IgE response to purified and recombinant allergens in latex allergy. Clin Mol Allergy. 2005, 3: 11-10.1186/1476-7961-3-11.
3. Yagami A, Suzuki K, Saito H, Matsunaga K: Hev B 6.02 is the most important allergen in health care workers sensitized occupationally by natural rubber latex gloves. Allergol Int. 2009, 58 (3): 347-355. 10.2332/allergolint.08-OA-0046.
4. Mari A, Scala E, D'Ambrosio C, Breiteneder H, Wagner S: Latex allergy within a cohort of not-at-risk subjects with respiratory symptoms: prevalence of latex sensitization and assessment of diagnostic tools. Int Arch Allergy Immunol. 2007, 143 (2): 135-143. 10.1159/000099080.
5. Smith AM, Amin HS, Biagini RE, Hamilton RG, Arif SA, Yeang HY, Bernstein DI: Percutaneous reactivity to natural rubber latex proteins persists in health-care workers following avoidance of natural rubber latex. Clin Exp Allergy. 2007, 37 (9): 1349-1356. 10.1111/j.1365-2222.2007.02787.x.
6. Pamies R, Oliver F, Raulf-Heimsoth M, Rihs HP, Barber D, Boquete M, Nieto A, Mazon A: Patterns of latex allergen recognition in children sensitized to natural rubber latex. Pediatr Allergy Immunol. 2006, 17 (1): 55-59. 10.1111/j.1399-3038.2005.00341.x.
7. Wagner B, Buck D, Hafner C, Sowka S, Niggemann B, Scheiner O, Breiteneder H: Hev b 7 is a hevea brasiliensis protein associated with latex allergy in children with spina bifida. J Allergy Clin Immunol. 2001, 108 (4): 621-627. 10.1067/mai.2001.118289.
8. Ganglberger E, Radauer C, Wagner S, Riordain G, Beezhold DH, Brehler R, Niggemann B, Scheiner O, Jensen-Jarolim E, Breiteneder H: Hev b 8, the hevea brasiliensis latex profilin, is a cross-reactive allergen of latex, plant foods and pollen. Int Arch Allergy Immunol. 2001, 125 (3): 216-227. 10.1159/000053819.
9. Wagner S, Breiteneder H, Simon-Nobbe B, Susani M, Krebitz M, Niggemann B, Brehler R, Scheiner O, Hoffmann-Sommergruber K: Hev b 9, an enolase and a new cross-reactive allergen from hevea latex and molds. Purification, characterization, cloning and expression. Eur J Biochem. 2000, 267 (24): 7006-7014. 10.1046/j.1432-1327.2000.01801.x.
10. Raulf-Heimsoth M, Rihs HP, Rozynek P, Cremer R, Gaspar A, Pires G, Yeang HY, Arif SA, Hamilton RG, Sander I: Quantitative analysis of immunoglobulin E reactivity profiles in patients allergic or sensitized to natural rubber latex (Hevea brasiliensis). Clin Exp Allergy. 2007, 37 (11): 1657-1667. 10.1111/j.1365-2222.2007.02833.x.
11. Draisci G, Zanfini BA, Nucera E, Catarci S, Sangregorio R, Schiavino D, Mannocci A, Patriarca G: Latex sensitization: a special risk for the obstetric population?. Anesthesiology. 2011, 114 (3): 565-569. 10.1097/ALN.0b013e318206ff50.
12. Deinhofer K, Sevcik H, Balic N, Harwanegg C, Hiller R, Rumpold H, Mueller MW, Spitzauer S: Microarrayed allergens for IgE profiling. Methods. 2004, 32 (3): 249-254. 10.1016/j.ymeth.2003.08.018.
13. Jahn-Schmid B, Harwanegg C, Hiller R, Bohle B, Ebner C, Scheiner O, Mueller MW: Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen-specific serum immunoglobulin E. Clin Exp Allergy. 2003, 33 (10): 1443-1449. 10.1046/j.1365-2222.2003.01784.x.
14. Sanz ML, Garcia-Aviles MC, Tabar AI, Anda M, Garcia BE, Barber D, Salcedo G, Rihs HP, Raulf-Heimsoth M: Basophil activation test and specific IgE measurements using a panel of recombinant natural rubber latex allergens to determine the latex allergen sensitization profile in children. Pediatr Allergy Immunol. 2006, 17 (2): 148-156. 10.1111/j.1399-3038.2005.00359.x.
15. Ebo DG, Hagendorens MM, Bridts CH, De Clerck LS, Stevens WJ: Sensitization to cross-reactive carbohydrate determinants and the ubiquitous protein profilin: mimickers of allergy. Clin Exp Allergy. 2004, 34 (1): 137-144. 10.1111/j.1365-2222.2004.01837.x.
16. Ebo DG, Hagendorens MM, De Knop KJ, Verweij MM, Bridts CH, De Clerck LS, Stevens WJ: Component-resolved diagnosis from latex allergy by microarray. Clin Exp Allergy. 2010, 40 (2): 348-358. 10.1111/j.1365-2222.2009.03370.x.
17. Bernstein DI, Biagini RE, Karnani R, Hamilton R, Murphy K, Bernstein C, Arif SA, Berendts B, Yeang HY: In vivo sensitization to purified hevea brasiliensis proteins in health care workers sensitized to natural rubber latex. J Allergy Clin Immunol. 2003, 111 (3): 610-616. 10.1067/mai.2003.164.
18. Santos A, Van Ree R: Profilins: mimickers of allergy or relevant allergens?. Int Arch Allergy Immunol. 2011, 155 (3): 191-204. 10.1159/000321178.
19. Antonicelli L, Micucci C, Mistrello G, Roncarolo D, Zanotta S, Cinti B, Garritani MS, Bonifazi F: Improving latex-allergy diagnosis: the clinical role of Hev b8-specific IgE. Allergy. 2008, 63 (5): 620-621. 10.1111/j.1398-9995.2008.01651.x.
20. Raulf-Heimsoth M, Kespohl S, Crespo JF, Rodriguez J, Feliu A, Bruning T, Rihs HP: Natural rubber latex and chestnut allergy: cross-reactivity or co-sensitization?. Allergy. 2007, 62 (11): 1277-1281. 10.1111/j.1398-9995.2007.01489.x.
21. Khan S, Holding S, Dore P, Sewell C: Pitfalls in the diagnosis of latex allergy. Allergol Int. 2010, 59 (3): 305-308. 10.2332/allergolint.09-OA-0154.
22. Unsel M, Mete N, Ardeniz O, Sin A, Gulbahar O, Kokuludag A: Diagnostic value of specific IgE analysis in latex allergy. Int Arch Allergy Immunol. 2012, 158 (3): 281-287. 10.1159/000332929.
23. Beezhold DH, Hickey VL, Kostyal DA, Puhl H, Zuidmeer L, van Ree R, Sussman GL: Lipid transfer protein from hevea brasiliensis (Hev b 12), a cross-reactive latex protein. Ann Allergy Asthma Immunol. 2003, 90 (4): 439-445. 10.1016/S1081-1206(10)61830-3.