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Volumn 12, Issue 103, 2015, Pages

Multi-scale modelling of the dynamics of cell colonies: Insights into cell-adhesion forces and cancer invasion from in silico simulations

Author keywords

Cell population modelling; Cell adhesion forces; E cadherin; Individual based modelling

Indexed keywords

BIOPHYSICS; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CELLS; DISEASES; TISSUE;

EID: 85005790455     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.1080     Document Type: Article
Times cited : (38)

References (28)
  • 1
    • 0002760170 scopus 로고
    • The cadherin/catenin complex: Connections to multiple cellular processes involved in cell adhesion, proliferation and morphogenesis
    • Näthke IS, Hinck L, Nelson WJ. 1995 The cadherin/catenin complex: connections to multiple cellular processes involved in cell adhesion, proliferation and morphogenesis. Sem. Dev. Biol. 6, 89-95. (doi:10. 1016/S1044-5781(06)80018-6).
    • (1995) Sem. Dev. Biol. , vol.6 , pp. 89-95
    • Näthke, I.S.1    Hinck, L.2    Nelson, W.J.3
  • 2
    • 0035117087 scopus 로고    scopus 로고
    • Developmental expression of catenins and associated proteins during sub mucosal gland morphogenesis in the airway
    • Ritchie T, Zhou W, McKinstry E, Hosch M, Zhang Y, Näthke IS, Engelhardt JF. 2001 Developmental expression of catenins and associated proteins during sub mucosal gland morphogenesis in the airway. Exp. Lung Res. 27, 121-141. (doi:10.1080/019021401750069375).
    • (2001) Exp. Lung Res. , vol.27 , pp. 121-141
    • Ritchie, T.1    Zhou, W.2    Mckinstry, E.3    Hosch, M.4    Zhang, Y.5    Näthke, I.S.6    Engelhardt, J.F.7
  • 3
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin mediated adhesion in morphogenesis
    • Gumbiner BM. 2005 Regulation of cadherin mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 6, 622-634. (doi:10.1038/nrm1699).
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 4
    • 11244352270 scopus 로고    scopus 로고
    • Force measurements in e-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through RAC and CDC42
    • Chu YS, Thomas WA, Eder O, Pincet E, Thiery JP, Dufour S. 2004 Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and CdC42. J. Cell Biol. 167, 1183-1194. (doi:10.1083/jcb. 200403043).
    • (2004) J. Cell Biol. , vol.167 , pp. 1183-1194
    • Chu, Y.S.1    Thomas, W.A.2    Eder, O.3    Pincet, E.4    Thiery, J.P.5    Dufour, S.6
  • 5
    • 46749151795 scopus 로고    scopus 로고
    • Modelling the influence of the ecadherin- b-catenin pathway in cancer cell invasion: A multi scale approach
    • Ramis-Conde I, Drasdo D, Anderson ARA, Chaplain MAJ. 2008 Modelling the influence of the Ecadherin- b-catenin pathway in cancer cell invasion: A multi scale approach. Biophys. J. 95, 155-165. (doi:10.1529/biophysj.107.114678).
    • (2008) Biophys. J. , vol.95 , pp. 155-165
    • Ramis-Conde, I.1    Drasdo, D.2    Anderson, A.R.A.3    Chaplain, M.A.J.4
  • 6
    • 33845414010 scopus 로고    scopus 로고
    • Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis
    • Halbleib JM, Nelson WJ. 2006 Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev. 20, 3199-3214. (doi:10.1101/gad.1486806).
    • (2006) Genes Dev. , vol.20 , pp. 3199-3214
    • Halbleib, J.M.1    Nelson, W.J.2
  • 7
    • 0028305138 scopus 로고
    • Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex assembly
    • Hinck L, Nathke I, Papkoff J, Nelson WJ. 1994 Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J. Cell Biol. 125, 1327-1340. (doi:10. 1083/jcb.125.6.1327).
    • (1994) J. Cell Biol. , vol.125 , pp. 1327-1340
    • Hinck, L.1    Nathke, I.2    Papkoff, J.3    Nelson, W.J.4
  • 8
    • 0033593803 scopus 로고    scopus 로고
    • Coupling assembly of the e-cadherin/beta-catenin complex to efficient endoplasmatic reticulum exit and basallateral membrane targeting of e-cadherin in polarized mdck cells
    • Chen YT, Stewart DB, Nelson WJ. 1999 Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmatic reticulum exit and basallateral membrane targeting of E-cadherin in polarized MDCK cells. J. Cell Biol. 144, 687-699. (doi:10.1083/jcb.144.4.687).
    • (1999) J. Cell Biol , vol.144 , pp. 687-699
    • Chen, Y.T.1    Stewart, D.B.2    Nelson, W.J.3
  • 9
    • 0001331879 scopus 로고    scopus 로고
    • Recycling of ecadherin: A potential mechanism for regulating cadherin dynamics
    • Le TL, Yap AS, Stow JL. 1999 Recycling of Ecadherin: A potential mechanism for regulating cadherin dynamics. J. Cell Biol. 146, 219-232. (doi:10.1083/jcb.146.1.219).
    • (1999) J. Cell Biol. , vol.146 , pp. 219-232
    • Le, T.L.1    Yap, A.S.2    Stow, J.L.3
  • 10
    • 57349114162 scopus 로고    scopus 로고
    • The cell-cell adhesion molecule E-cadherin
    • van Roy F, Berx G. 2008 The cell-cell adhesion molecule E-cadherin. Cell. Mol. Life Sci. 65, 3756-3788. (doi:10.1007/s00018-008-8281-1).
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3756-3788
    • Van Roy, F.1    Berx, G.2
  • 11
    • 4143146438 scopus 로고    scopus 로고
    • The ins and outs of e-cadherin trafficking
    • Bryant DM, Stow JL. 2004 The ins and outs of E-cadherin trafficking. Trends Cell Biol. 14, 427-434. (doi:10.1016/j.tcb.2004.07.007).
    • (2004) Trends Cell Biol. , vol.14 , pp. 427-434
    • Bryant, D.M.1    Stow, J.L.2
  • 12
    • 0001559087 scopus 로고
    • Ueber die beruehrung fester elastischer koerper
    • Hertz H. 1881 Ueber die Beruehrung fester elastischer Koerper. J. die reine und Angew. Math. 92, 156-171.
    • (1881) J. Die Reine Und Angew. Math. , vol.92 , pp. 156-171
    • Hertz, H.1
  • 13
    • 11244250625 scopus 로고    scopus 로고
    • Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro
    • Galle J, Loeffler M, Drasdo D. 2005 Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro. Biophys. J. 88, 62-75. (doi:10.1529/biophysj.104.041459).
    • (2005) Biophys. J. , vol.88 , pp. 62-75
    • Galle, J.1    Loeffler, M.2    Drasdo, D.3
  • 14
    • 65349115288 scopus 로고    scopus 로고
    • Multi-scale modelling of cancer cell intra vasation: The role of cadherins in metastasis
    • Ramis-Conde I, Chaplain MAJ, Anderson ARA, Drasdo D. 2009 Multi-scale modelling of cancer cell intra vasation: The role of cadherins in metastasis. Phys. Biol. 6, 016008. (doi:10.1088/1478-3975/6/1/016008).
    • (2009) Phys. Biol. , vol.6 , pp. 016008
    • Ramis-Conde, I.1    Chaplain, M.A.J.2    Anderson, A.R.A.3    Drasdo, D.4
  • 15
    • 26944481103 scopus 로고    scopus 로고
    • A single-cell-based model of tumor growth in vitro: Monolayers and spheroids
    • Drasdo D, Hoehme S. 2005 A single-cell-based model of tumor growth in vitro: monolayers and spheroids. Phys. Biol. 2, 133-147. (doi:10.1088/1478-3975/2/3/001).
    • (2005) Phys. Biol. , vol.2 , pp. 133-147
    • Drasdo, D.1    Hoehme, S.2
  • 17
    • 34447508363 scopus 로고    scopus 로고
    • Why do cells cycle with a 24 hour period?
    • Bernard S, Herzel H. 2006 Why do cells cycle with a 24 hour period? Genome Inform. 17, 72-79.
    • (2006) Genome Inform , vol.17 , pp. 72-79
    • Bernard, S.1    Herzel, H.2
  • 18
    • 0001376559 scopus 로고
    • Contact inhibition, macromolecular synthesis, and poly ribosomes in cultured human diploid fibroblasts
    • Levine EM, Becker Y, Boone CW. 1965 Contact inhibition, macromolecular synthesis, and polyribosomes in cultured human diploid fibroblasts. Proc. Natl Acad. Sci. USA 53, 350-356. (doi:10.1073/pnas.53.2.350).
    • (1965) Proc. Natl Acad. Sci. USA , vol.53 , pp. 350-356
    • Levine, E.M.1    Becker, Y.2    Boone, C.W.3
  • 19
    • 0030589575 scopus 로고    scopus 로고
    • Cell contact dependent signaling
    • Fagotto F, Gumbiner BM. 1996 Cell contact dependent signaling. Dev. Biol. 180, 445-454. (doi:10.1006/dbio.1996.0318).
    • (1996) Dev. Biol. , vol.180 , pp. 445-454
    • Fagotto, F.1    Gumbiner, B.M.2
  • 20
    • 84866509184 scopus 로고    scopus 로고
    • Computational modeling of single cell migration: The leading role of extracellular matrix fibers
    • Schlüter DK, Ramis-Conde I, Chaplain MAJ. 2012 Computational modeling of single cell migration: The leading role of extracellular matrix fibers. Biophys. J. 103, 1141-1151. (doi:10.1016/j.bpj. 2012.07.048).
    • (2012) Biophys. J. , vol.103 , pp. 1141-1151
    • Schlüter, D.K.1    Ramis-Conde, I.2    Chaplain, M.A.J.3
  • 21
    • 33748313224 scopus 로고    scopus 로고
    • The emergence of geometric order in proliferating metazoan epithelia
    • Gibson MC, Patel AB, Nagpal R, Perrimon N. 2006 The emergence of geometric order in proliferating metazoan epithelia. Nature 442, 1038-1041. (doi:10.1038/nature05014).
    • (2006) Nature , vol.442 , pp. 1038-1041
    • Gibson, M.C.1    Patel, A.B.2    Nagpal, R.3    Perrimon, N.4
  • 22
    • 79955712939 scopus 로고    scopus 로고
    • Correlaing cell behaviour with tissue topology in embryonic epithelia
    • Sanderius SA, Chuai M, Weijer CJ, Newman TJ. 2011 Correlaing cell behaviour with tissue topology in embryonic epithelia. PLoS ONE 6, e18081. (doi:10. 1371/journal.pone.0018081).
    • (2011) PLoS ONE , vol.6 , pp. e18081
    • Sanderius, S.A.1    Chuai, M.2    Weijer, C.J.3    Newman, T.J.4
  • 23
    • 77249161680 scopus 로고    scopus 로고
    • Synergistic antitumor effects of combined cathepsin b and cathepsin z deficiencies on breast cancer progression and metastasis in mice
    • Sevenich L et al. 2010 Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. Proc. Natl Acad. Sci. USA 107, 2497-2502. (doi:10.1073/pnas. 0907240107).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 2497-2502
    • Sevenich, L.1
  • 26
    • 14244268497 scopus 로고    scopus 로고
    • Separation force measurements reveal different types of modulation of e-cadherin-based adhesion by nectin-1 and -3
    • Martinez-Rico C, Pincet F, Perez E, Thiery JP, Shimizu K, Takai Y, Dufour S. 2005 Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3∗. J. Biol. Chem. 280, 4753-4760. (doi:10.1074/jbc. M412544200).
    • (2005) J. Biol. Chem. , vol.280 , pp. 4753-4760
    • Martinez-Rico, C.1    Pincet, F.2    Perez, E.3    Thiery, J.P.4    Shimizu, K.5    Takai, Y.6    Dufour, S.7
  • 28
    • 0023405068 scopus 로고
    • A dynamical model for receptor-mediated cell adhesion to surfaces
    • Hammer DA, Lauffenburger DA. 1987 A dynamical model for receptor-mediated cell adhesion to surfaces. Biophys. J. 52, 475-487. (doi:10.1016/S0006-3495(87)83236-8).
    • (1987) Biophys. J. , vol.52 , pp. 475-487
    • Hammer, D.A.1    Lauffenburger, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.