A simple fragment of cyclic acyldepsipeptides is necessary and sufficient for ClpP activation and antibacterial activity

Chembiochem : a European journal of chemical biology

Volumn 15, Issue 15, 2014, Pages 2216-2220

  Carney, Daniel W ^a   Compton, Corey L ^a   Schmitz, Karl R ^a   Stevens, Julia P ^a   Sauer, Robert T ^a   Sello, Jason K ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

antibacterials; ClpP; fragments; peptides; proteolysis

Indexed keywords

ANTIINFECTIVE AGENT; DEPSIPEPTIDE; ENDOPEPTIDASE CLP;

ANTAGONISTS AND INHIBITORS; BACILLUS SUBTILIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; DEPSIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASE CLP; ENZYME ACTIVATION; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85005790393     PISSN: None     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201402358     Document Type: Article

References (0)