Mapping the decision pathways of acute infection management in secondary care among UK medical physicians: A qualitative study

BMC Medicine

Volumn 14, Issue 1, 2016, Pages

  Rawson, Timothy Miles ^a,d   Charani, Esmita ^a   Moore, Luke Stephen Prockter ^a,b   Hernandez, Bernard ^c   Castro Sánchez, Enrique ^a   Herrero, Pau ^c   Georgiou, Pantelis ^c   Holmes, Alison Helen ^a,b  

^a The National Institute for Health Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with UK Health Security Agency   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Antibiotics; Antimicrobial stewardship; Grounded theory; Prescriber; Sepsis

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; ARTICLE; CLINICAL DECISION MAKING; COHORT ANALYSIS; FRUSTRATION; HEALTH CARE DISPARITY; HUMAN; INFECTION; INFECTION CONTROL; PHYSICIAN ATTITUDE; PRACTICE GUIDELINE; QUALITATIVE RESEARCH; SECONDARY HEALTH CARE; UNITED KINGDOM; BAYES THEOREM; CLINICAL PRACTICE; DECISION MAKING; DRUG THERAPY; HEALTH PERSONNEL ATTITUDE; INTERPERSONAL COMMUNICATION; MALE; PHYSICIAN;

ANTI-INFECTIVE AGENTS; ATTITUDE OF HEALTH PERSONNEL; BAYES THEOREM; COMMUNICATION; DECISION MAKING; HUMANS; INFECTIONS; MALE; PHYSICIANS; PRACTICE PATTERNS, PHYSICIANS'; QUALITATIVE RESEARCH; SECONDARY CARE;

EID: 85003633058     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-016-0751-y     Document Type: Article

References (38)

1. O'Neill J. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. 2014. https://amr-review.org/Publications.
2. Holmes AH, Moore LSP, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, Guerin PJ, Piddock LJV. Understanding the mechanisms and drivers of antimicrobial resistance. Lancet. 2016;387(10014):176-87. doi: 10.1016/S0140-6736(15)00473-0.
3. Littmann J, Viens A. The ethical significance of antimicrobial resistance. Public Health Ethics. 2015;8(3):209-24.
4. Pulcini C, Williams F, Molinari N, Davey P, Nathwani D. Junior doctors' knowledge and perceptions of antibiotic resistance and prescribing: a survey in France and Scotland. Clin Microbiol Infect. 2011;17:80-7.
5. Teixeira Rodrigues A, Roque F, Falcão A, Figueiras A, Herdeiro MT. Understanding physician antibiotic prescribing behaviour: A systematic review of qualitative studies. Int J Antimicrob Agents. 2013;41:203-12.
6. Doyle MP, Loneragan GH, Scott HM, Singer RS. Antimicrobial resistance: Challenges and perspectives. Compr Rev Food Sci Food Saf. 2013;12:234-48.
7. Charani E, Castro-Sanchez E, Sevdalis N, Kyratsis Y, Drumright L, Shah N, Holmes A. Understanding the determinants of antimicrobial prescribing within hospitals: The role of "prescribing etiquette". Clin Infect Dis. 2013;57:188-96.
8. Charani E, Edwards R, Sevdalis N, Alexandrou B, Sibley E, Mullett D, Franklin BD, Holmes A. Behavior change strategies to influence antimicrobial prescribing in acute care: a systematic review. Clin Infect Dis. 2011;53:651-62.
9. Davey P, Brown E, Charani E, Fenelon L, Gould IM, Holmes A, Ramsay CR, Wiffen PJ, Wilcox M. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev. 2013;4:CD003543.
10. Lake Research Partners. Informing and Involving Patients in Medical Decisions: The Primary Care Physicians Perspective. 2009. http://www.hospitalmanagement.net/downloads/whitepapers/cleaning/1596/.
11. Coxeter P, Del Mar CB, McGregor L, Beller EM, Hoffmann TC. Interventions to facilitate shared decision making to address antibiotic use for acute respiratory infections in primary care. Cochrane Database Syst Rev. 2015;11:CD010907.
12. Jevsevar DS. Shared decision making tool: should I take antibiotics before my dental procedure? J Am Acad Orthop Surg. 2013;21:190-2.
13. Public Health England, Department of Health. Behaviour change and antibiotic prescribing in healthcare settings Literature review and behavioural analysis. 2015. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/405031/Behaviour_Change_for_Antibiotic_Prescribing_-_FINAL.pdf.
14. Pulcini C, Gyssens IC. How to educate prescribers in antimicrobial stewardship practices. Virulence. 2013;4:192-202.
15. Rawson TM, Gill D, Buckley J, Renton S. The role of the multidisciplinary team in decision making for vascular graft infection. J Vasc Surg. 2015;62:1686.
16. Epstein N. Multidisciplinary in-hospital teams improve patient outcomes: A review. Surg Neurol Int. 2014;5:295.
17. Bornard L, Dellamonica J, Hyvernat H, Girard-Pipau F, Molinari N, Sotto A, Roger PM, Bernardin G, Pulcini C. Impact of an assisted reassessment of antibiotic therapies on the quality of prescriptions in an intensive care unit. Med Mal Infect. 2011;41:480-5.
18. Pulcini C, Botelho-Nevers E, Dyar OJ, Harbarth S. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect. 2014;20:963-72.
19. Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control. 2008;36:283-90.
20. Rimawi RH, Mazer M, Siraj DS, Gooch M, Cook PP. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med. 2013;41:2099-107.
21. Taggart LR, Leung E, Muller MP, Matukas LM, Daneman N. Differential outcome of an antimicrobial stewardship audit and feedback program in two intensive care units: a controlled interrupted time series study. BMC Infect Dis. 2015;15:480.
22. Strauss A, Corbin J. Grounded theory methodology. In: Handbook of Qualitative Research. Thousand Oaks: Sage; 1994. p. 273-85.
23. Walker D, Myrick F. Grounded theory: an exploration of process and procedure. Qual Health Res. 2006;16:547-59.
24. Coyne IT. Sampling in qualitative research. Purposeful and theoretical sampling; merging or clear boundaries? J Adv Nurs. 1997;26:623-30.
25. Willig C. Introducing qualitative research in psychology. Maidenhead, England: McGraw Hill/Open University Press. 2008;69-82.
26. Charmaz K. Constructing Grounded Theory: A Practical Guide through Qualitative Analysis, vol. 10. London: Sage Publications; 2006.
27. Barry CA, Britten N, Barber N, Bradley C, Stevenson F. Teamwork in qualitative research. Heal (San Fr). 1999;9:26-44.
28. Pope C, Ziebland S, Mays N. Analysing qualitative data. Nurse Res. 2011;18:4-5.
29. Lewis PJ, Tully MP. Uncomfortable prescribing decisions in hospitals: the impact of teamwork. J R Soc Med. 2009;102:481-8.
30. Livorsi D, Comer A, Matthias MS, Perencevich EN, Bair MJ. Factors influencing antibiotic-prescribing decisions among inpatient physicians: a qualitative investigation. Infect Control Hosp Epidemiol. 2015;36:1065-72.
31. ESPAUR SSTF Implementation subgroup. Start Smart - Then Focus Antimicrobial Stewardship Toolkit for English Hospitals. 2015. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/417032/Start_Smart_Then_Focus_FINAL.PDF.
32. Cooke FJ, Franklin BD, Lawson W, Jacklin A, Holmes A. Multidisciplinary hospital antibiotic stewardship: a West London model. Clin Gov An Int J. 2004;9:237-43.
33. Edwards R, Drumright LN, Kiernan M, Holmes A. Covering more territory to fight resistance: considering nurses' role in antimicrobial stewardship. J Infect Prev. 2011;12:6-10.
34. Dellit TH, Owens RC, McGowan JE, Gerding DN, Weinstein RA, Burke JP, Huskins WC, Paterson DL, Fishman NO, Carpenter CF, Brennan PJ, Billeter M, Hooton TM. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2007;44:159-77.
35. Department of Health, Department for Environment Food and Rural Affairs. UK Five Year Antimicrobial Resistance Strategy 2013 to 2018. 2013. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/244058/20130902_UK_5_year_AMR_strategy.pdf.
36. Thursky KA, Mahemoff M. User-centered design techniques for a computerised antibiotic decision support system in an intensive care unit. Int J Med Inform. 2007;76:760-8.
37. De Souza V, MacFarlane A, Murphy AW, Hanahoe B, Barber A, Cormican M. A qualitative study of factors influencing antimicrobial prescribing by non-consultant hospital doctors. J Antimicrob Chemother. 2006;58:840-3.
38. Montravers P, Dupont H, Gauzit R, Veber B, Bedos J-P, Lepape A. Strategies of initiation and streamlining of antibiotic therapy in 41 French intensive care units. Crit Care. 2011;15:R17.