Caution: Reactivation of Hepatitis B during Hepatitis C Treatment with Direct-Acting Antiviral Therapy

American Journal of Gastroenterology

Volumn 111, Issue 12, 2016, Pages 1854-1856

  Pillai, Anjana A ^a   Anania, Frank A ^b   Pearlman, Brian L ^b,c  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENTECAVIR; HEPATITIS B CORE ANTIBODY; SIMEPREVIR; SOFOSBUVIR; TENOFOVIR; ANTIVIRUS AGENT; GUANINE;

ADULT; AGED; ANTIVIRAL THERAPY; CASE REPORT; DRUG WITHDRAWAL; ELASTOGRAPH; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HUMAN; LETTER; MALE; MIDDLE AGED; MIXED INFECTION; PORTAL HYPERTENSION; PRACTICE GUIDELINE; PRIORITY JOURNAL; SUSTAINED VIROLOGIC RESPONSE; VIRUS LOAD; VIRUS REACTIVATION; VIRUS REPLICATION; ANALOGS AND DERIVATIVES; CHRONIC HEPATITIS B; CHRONIC HEPATITIS C; COMBINATION DRUG THERAPY; VIRUS ACTIVATION;

AGED; ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; GUANINE; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; MALE; MIDDLE AGED; SIMEPREVIR; SOFOSBUVIR; TENOFOVIR; VIRAL LOAD; VIRUS ACTIVATION;

EID: 85003601703     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2016.422     Document Type: Letter

References (10)

1. Bini EJ, Perumalswami PV. Hepatitis B virus infection among American patients with chronic hepatitis C virus infection: prevalence, racial/ethnic diff erences and viral interactions. Hepatology 2010; 51: 759-66.
2. Liu JY, Sheng YJ, Hu HD et al. Th e influence of hepatitis B virus on antiviral treatment with interferon and ribavirin in Asian patients with hepatitis C virus/hepatitis B virus coinfection: a meta-analysis. Virol J. 2012; 9: 186.
3. Chu CM, Yeh CT, Liaw YF. Low-level viremia and intracellular expression of hepatitis B surface antigen (HBsAg) in HBsAg carriers with concurrent hepatitis C virus infection. J Clin Microbiol. 1998; 36: 2084-6.
4. Liaw YF, Chen YC, Sheen IS et al. Impact of acute hepatitis C virus superinfection in patients with chronic hepatitis B virus infection. Gastroenterology 2004; 126: 1024-9.
5. Biliotti E, Kondili LA, Furlan C et al. Acute hepatitis B in patients with or without underlying chronic HCV infection. J Infect. 2008; 57: 152-7.
6. Bellecave P, Gouttenoire J, Gajer M et al. Hepatitis B and C virus coinfection: a novel model system reveals the absence of direct viral interference. Hepatology 2009; 50: 46-55.
7. Collins JM, Raphael KL, Terry C et al. Hepatitis B virus reactivation during successful treatment of HCV with sofosbuvir and simeprevir. Clin Infect Dis. 2015; 61: 1304-6.
8. De Monte A, Courjon J, Anty R et al. Directacting antiviral treatment in adults infected with hepatitis C virus: Reactivation of hepatitis B virus coinfection as a further challenge. J Clin Virol 2016; 78: 27-30.
9. Takayama H, Sato T, Ikeda F et al. Reactivation of hepatitis B virus during interferon-free therapy with daclatasvir and asunaprevir in patient with hepatitis B virus/hepatitis C virus co-infection. Hepatol Res. 2016; 46: 489-91.
10. Ende AR, Kim NH, Yeh MM et al. Fulminant hepatitis B reactivation leading to liver transplantation in a patient with chronic hepatitis C treated with simeprevir and sofosbuvir: a case report. J Med Case Rep 2015; 9: 164.