Modulation of osteoclast differentiation

Endocrine Reviews

Volumn 13, Issue 1, 1992, Pages 66-80

  Suda, Tatsuo ^a   Takahashi, Naoyuki ^a   Martin, T John ^b  

^a SHOWA UNIVERSITY   (Japan)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; COLECALCIFEROL; COLONY STIMULATING FACTOR 1; CYTOKINE; PARATHYROID HORMONE; PROSTAGLANDIN E2; PROTEIN TYROSINE KINASE;

BONE DEVELOPMENT; BONE MARROW CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL ULTRASTRUCTURE; HEMATOPOIETIC CELL; MACROPHAGE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STEM CELL;

NON-PROGRAMMATIC;

ANIMAL; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; OSTEOCLASTS; PROTEIN-TYROSINE KINASE; SIGNAL TRANSDUCTION;

EID: 85003152202     PISSN: 0163769X     EISSN: None     Source Type: Journal    
DOI: 10.1210/edrv-13-1-66     Document Type: Article

References (112)

1. Marks Jr SC 1983 The origin of osteoclasts: evidence, clinical implications and investigative challenges of an extra-skeletal source. J Pathol 12:226
2. Mundy GR, Roodman GD 1987 Osteoclast ontogeny and function. In: Peck WA (ed) Bone and Mineral Research. Elsevier Science Publishers, New York, vol 5:209
3. Nijweide PJ, Burger EH, Feyen JHM 1986 Cells of bone: proliferation, differentiation and hormonal regulation. Physiol Rev 66:855
4. 3 integrin is colocalized with vinculin and talin in the podosomes of osteoclastoma giant cells. Exp Cell Res 182:645
5. Teti A, Marchisio PC, Zambonin-Zallone A 1991 Clear zone in osteoclast function. Role of podosomes in regulation of boneresorbing activity. Am J Physiol 261:C1
6. Hammarstrom LE, Hanker JS, Toverud SU 1971 Cellular differences in acid phosphatase isoenzymes in bone and teeth. Clin Orthop 78:151
7. Minkin C 1982 Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function. Calcif Tissue Int 34:285
8. Chambers TJ, Magnus CJ 1982 Calcitonin alters behaviour of isolated osteoclasts. J Pathol 136:27
9. Nicholson GC, Moseley JM, Sexton PM, Mendelsohn FAO, Martin TJ 1986 Abundant calcitonin receptors in isolated rat osteoclasts. J Clin Invest 78:355
10. 3 in osteoclast-like multinucleated cells formed from mouse bone marrow cells. Endocrinology 123:1504
11. Hattersley G, Chambers TJ 1989 Calcitonin receptors as markers for osteoclastic differentiation: correlation between generation of bone-resorptive cells and cells that express calcitonin receptors in mouse bone marrow cultures. Endocrinology 125:1606
12. 2 on cyclic AMP levels of isolated osteoclasts. Comp Biochem Physiol 81A:653
13. Nicholson GC, Moseley JM, Sexton PM, Martin TJ 1987 Chicken osteoclasts do not possess calcitonin receptors. J Bone Miner Res 2:53
14. Davies J, Warwick J, Totty N, Philp R, Helfrich M, Horton M 1989 The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. J Cell Biol 109:1817
15. Chambers TJ, Fuller K, Darby JA, Pringle JAS, Horton MA 1986 Monoclonal antibodies against osteoclasts inhibit bone resorptio» in vitro. Bone Min 1:127
16. Horton MA, Taylor ML, Arnett TR, Helfrich MH 1991 Arg-Gly-Asp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts. Exp Cell Res 195:368
17. Sato M, Sardana MK, Grasser WA, Garsky VM, Murray JM, Gould RJ 1990 Echistatin is a potent inhibitor of bone resorption in culture. J Cell Biol 111:1713
18. Reinholt FP, Hultenby K, Oldberg A, Heinegard D 1990 Osteopontin-a possible anchor of osteoclasts to bone. Proc Natl Acad Sci USA 87:4473
19. Baron R, Neff L, Louvard D, Courtoy PJ 1985 Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border. J Cell Biol 101:2210
20. Silver IA, Murrills RJ, Etherington DJ 1988 Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp Cell Res 175:266
21. Blair HC, Teitelbaum SL, Chiselli R, Gluck S 1989 Osteoclastic bone resorption by a polarized vacuolar proton pump. Science 245:855
22. +-ATPase type in the ruffled borders of osteoclasts. J Cell Biol 111:1305
23. 1 abolishes bone resorption. Biochem Biophys Res Commun 168:309
24. +-ATPase of avian osteoclasts. Am J Physiol 260:C1315
25. Kenny AD 1985 Role of carbonic anhydrase in bone: partial inhibition of disuse atrophy of bone by parenteral acetazolamide. Calcif Tissue Int 37:126
26. Väänänen HK 1984 Immunohistochemical localization of carbonic anhydrase isoenzymes I and II in human bone, cartilage and giant cell tumor. Histochemistry 81:485
27. Sly WS, Whyte MP, Sundaram V, Tashian RE, Hewett-Emmett D, Guibaud P, Vainesel M, Baluarte HJ, Gruskin A, Al-Mosawi M, Sakati N, Ohlsson A 1985 Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. N Engl J Med 313:139
28. Pierce Jr WM, Waite LC 1987 Bone-targeted carbonic anhydrase inhibitors: effect of a proinhibitor on bone resorption in vitro. Proc Soc Exp Biol Med 186:96
29. Brown GM, Morris CA, Mitnick MA, Insogna KL1990 Treatment of humoral hypercalcemia of malignancy in rats with inhibitors of carbonic anhydrase. J Bone Miner Res 5:1037
30. Teti A, Blair HC, Teitelbaum SL, Kahn AJ, Koziol C, Konsek J, Zambonin-Zallone A, Schlesinger PH 1989 Cytoplasmic pH regulation and chloride/bicarbonate exchange in avian osteoclasts. J Clin Invest 83:227
31. Blair HC, Kahn AJ, Crouch EC, Jeffrey JJ, Teitelbaum SL 1986 Isolated osteoclasts resorb the organic and inorganic components of bone. J Cell Biol 102:1164
32. Baron R 1989 Molecular mechanisms of bone resorption by the osteoclast. Anat Rec 224:317
33. Vaes G 1988 Cellular biology and biochemical mechanism of bone resorption, A review of recent developments on the formation, activation, and mode of action of osteoclasts. Clin Orthop 231:239
34. Delaisse JM, Eeckhout Y, Vaes G 1984 In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption. Biochem Biophys Res Commun 125:441
35. Wood GW, Neff JR, Gollahon KA, Gourley WK 1978 Macrophages in giant cell tumors of bone. J Pathol 125:53
36. Chambers TJ 1985 The pathobiology of the osteoclast. J Clin Pathol 38:241
37. Siminia T, Dijkstra CD 1986 The origin of osteoclasts: an immunohistochemical study on macrophages and osteoclasts in embryonic rat bone. Calcif Tissue Int 39:263
38. Brecher M, Franklin WA, Simon MA 1986 Immunohistochemical study of mononuclear phagocyte antigens in giant cell tumor of bone. Am J Pathol 125:252
39. Athanasou NA, Quinn J 1990 Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function. J Clin Pathol 43:997
40. Nijweide PJ, Vrijheid-Lammers T, Mulder RJP, Blok J 1985 Cell surface antigens on osteoclasts and related cells in the quail studied with monoclonal antibodies. Histochemistry 83:315
41. Chambers TJ 1979 Phagocytosis and trypsin-resistant glass adhesion by osteoclasts in culture. J Pathol 127:55
42. Horton MA, Lewis D, McNulty K, Pringle JAS, Chambers TJ 1985 Human fetal osteoclasts fail to express macrophage antigens. Br J Exp Pathol 66:103
43. Göthlin G, Ericsson JLE1976 The osteoclast: review of ultrastructure, origin, and structure-function relationship. Clin Orthop 120:201
44. Kahn AJ, Simmons DJ 1975 Investigation of cell lineage in bone using a chimaera of chick and quail embryonic tissue. Nature 268:325
45. Walker DG 1973 Osteopetrosis in mice cured by temporary parabiosis. Science 180:875
46. Walker DG 1975 Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells. Science 190:784
47. Walker DG 1975 Spleen cells transmit osteopetrosis in mice. Science 190:785
48. Ash P, Loutit JF, Townsend KMS 1980 Osteoclasts derived from haematopoietic stem cells. Nature 283:669
49. Raisz LG 1963 Stimulation of bone resorption by parathyroid hormone in tissue culture. Nature 197:1015
50. Teitelbaum SL, Stewart CC, Kahn AJ 1979 Rodent peritoneal macrophages as bone resorbing cells. Calcif Tissue Int 27:255
51. 3. Proc Natl Acad Sci USA 80:5907
52. 3 and lipopolysaccharides. Calcif Tissue Int 39:28
53. Burger EH, van der Meer JWM, van de Gevel JS, Gribnau JC, Thesingh CW, van Furth R 1982 In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes. J Exp Med 156:1604
54. Scheven BAA, Visser JWM, Nijweide PJ 1986 In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population. Nature 321:79
55. Hagenaars CE, van der kraan AAM, Kawilarang-de Haas EWM, Visser JWM, Nijweide PJ 1989 Osteoclast formation from cloned pluripotent hemopoietic stem cells. Bone Miner 6:179
56. Hagenaars CE, van der Kraan AAM, Kawilarang-de Haas EWM, Spooncer E, Dexter TM, Nijweide PJ 1990 Interleukin-3 dependent hemopoietic stem cell lines are capable of osteoclast formation in vitro: a model system for the study on osteoclast formation. In: Cohn DV, Glorieux EH, Martin TJ (eds) Calcium Regulation and Bone Metabolism. Elsevier Science Publishers, New York, p 280
57. Takahashi N, Yamana H, Yoshiki S, Roodman DG, Mundy GR, Jones SJ, Boyde A, Suda T 1988 Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 122:1373
58. Shinar DM, Sato M, Rodan GA 1990 The effect of hemopoietic growth factors on the generation of osteoclast-like cells in mouse bone marrow cultures. Endocrinology 126:1728
59. Testa NG, Allen TD, Lajtha LG, Onions D, Jarret O 1981 Generation of osteoclasts in vitro. J Cell Sci 47:127
60. Ibbotson KJ, Roodman GD, McManus LM, Mundy GR 1984 Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells. J Cell Biol 99:471
61. 3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow. Proc Natl Acad Sci USA 82:8213
62. MacDonald BR, Takahashi N, McManus LM, Holahan J, Mundy GR, Roodman GD 1987 Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures. Endocrinology 120:2326
63. Fuller K, Chambers TJ 1987 Generation of osteoclasts in cultures of rabbit bone marrow and spleen cells. J Cell Physiol 132:441
64. Kurihara N, Chenu C, Miller M, Civin C, Roodman GD 1990 Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures. Endocrinology 126:2733
65. Kurihara N, Gluck S, Roodman GD 1990 Sequential expression of phenotype markers for osteoclasts during differentiation of precursors for multinucleated cells formed in long term human marrow cultures. Endocrinology 127:3215
66. Kurihara N, Suda T, Miura Y, Nakauchi H, Kodama H, Hiura K, Hakeda Y, Kumegawa M 1989 Generation of osteoclasts from isolated hematopoietic progenitor cells. Blood 74:1295
67. Hakeda Y, Hiura K, Sato T, Okazaki R, Matsumoto T, Ogata E, Ishitani R, Kumegawa M 1989 Existence of parathyroid hormone binding sites on murine hemopoietic blast cells. Biochem Biophys Res Commun 163:1481
68. Akatsu T, Takahashi N, Udagawa N, Sato K, Nagata N, Moseley JM, Martin TJ, Suda T 1989 Parathyroid hormone (PTH)-related protein is a potent stimulator of osteoclast-like multinucleated cell formation to the same extent as PTH in mouse marrow cultures. Endocrinology 125:20
69. Akatsu T, Takahashi N, Debari K, Morita I, Murota S, Nagata N, Takatani O, Suda T 1989 Prostaglandins promote osteoclastlike cell formation by a mechanism involving cyclic adenosine 3′,5′-monophosphate in mouse bone marrow cell cultures. J Bone Miner Res 4:29
70. Akatsu T, Takahashi N, Udagawa N, Imamura K, Yamaguchi A, Sato K, Nagata N, Suda T 1991 Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro. J Bone Miner Res 6:183
71. 3 have ruffled borders and resorb dentine. Anat Rec 224:379
72. Hattersley G, Chambers TJ 1989 Generation of osteoclastic function in mouse bone marrow cultures: multinuclearity and tartrateresistant acid phosphatase are unreliable markers for osteoclastic differentiation. Endocrinology 124:1689
73. Modderman WE, Tuinenburg-Bol Raap AC, Nijweide PJ 1991 Tartrate-resistant acid phosphatase is not an exclusive marker for mouse osteoclasts in cell culture. Bone 12:81
74. Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T 1988 Osteoblastic cells are involved in osteoclast formation. Endocrinology 123:2600
75. Udagawa N, Takahashi N, Akatsu T, Sasaki T, Yamaguchi A, Kodama H, Martin TJ, Suda T 1989 The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclastlike cell differentiation in cocultures with mouse spleen cells. Endocrinology 125:1805
76. Udagawa N, Takahashi N, Akatsu T, Tanaka H, Sasaki T, Nishihara T, Koga T, Martin TJ, Suda T 1990 Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci USA 87:7260
77. Jee WSS, Nolan PD 1963 Origin of osteoclasts from the fusion of phagocytes. Nature 200:225
78. Zambonin-Zallone A, Teti A, Primavera MV 1984 Monocytes from circulating blood fuse in vitro with purified osteoclasts in primary culture. J Cell Sci 66:335
79. Burger EH, van der Meer JWM, Nijweide PJ 1984 Osteoclast formation from mononuclear phagocytes: role of bone-forming cells. J Cell Biol 99:1901
80. Hattersley G, Kerby JA, Chambers TJ 1991 Identification of osteoclast precursors in multilineage hemopoietic colonies. Endocrinology 128:259
81. Schneider GB, Relfson M 1988 The effects of transplantation of granulocyte-macrophage progenitors on bone resorption in osteopetrotic rats. J Bone Miner Res 3:225
82. Johnston RB 1988 Monocytes and macrophages. N Engl J Med 318:747
83. Rodan GA, Martin TJ 1981 Role of osteoblasts in hormonal control of bone resorption. A hypothesis. Calcif Tissue Int 33:349
84. Ejiri S 1983 The preosteoclast and its cytodifferentiation into the osteoclast: ultrastructural and histochemical studies of rat fetal parietal bone. Arch Histol Jpn 46:533
85. Yamashita T, Asano K, Takahashi N, Akatsu T, Udagawa N, Sasaki T, Martin TJ, Suda T 1990 Cloning of an osteoblastic cell line involved in the formation of osteoclast-like cells. J Cell Physiol 145:587
86. Rouleau MF, Mitchell J, Goltzman D 1990 Characterization of the major parathyroid hormone target cell in the endosteal metaphysis of rat long bones. J Bone Miner Res 5:1043
87. Baron R, Neff L, Van PT, Nefussi J-R, Vignery A 1986 Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multinucleated osteoclasts. Am J Pathol 122:363
88. 3 receptors on osteoclasts of calcium-deficient chicken despite demonstrable receptors on circulating monocytes. J Clin Invest 77:312
89. Nicholson GC, Moseley JM, Yates AJP, Martin TJ 1987 Control of cyclic adenosine 3′,5′-monophosphate production in osteoclasts: calcitonin-induced persistent activation and homologous desensitization of adenylate cyclase. Endocrinology 120:1902
90. Chambers TJ, Fuller K, McSheehy PMJ, Pringle JAS 1985 The effects of calcium regulating hormones on bone resorption by isolated human osteoclastoma cells. J Pathol 145:297
91. Marks Jr SC 1989 Osteoclast biology: lessons from mammalian mutations. Am J Med Genet 34:43
92. Marks Jr SC, Seifert MF, McGuire JL 1984 Congenitally osteopetrotic (op/op) mice are not cured by transplants of spleen or bone marrow cells from normal littermates. Metab Bone Dis Relat Res 5:183
93. Seifert MF, Marks Jr SC 1985 Morphological evidence of reduced bone resorption in the osteosclerotic (oc) mouse. Am J Anat 172:141
94. Marks Jr SC 1984 Congenital osteopetrotic mutations as probes of the origin, structure, and function of osteoclasts. Clin Orthop Relat Res 189:239
95. Wiktor-Jedrzejczak W, Ahmed A, Szczylik C, Skelly RR 1982 Hematological characterization of congenital osteopetrosis in op/ op mouse. Possible mechanism for abnormal macrophage differentiation. J Exp Med 156:1516
96. Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H, Sudo T, Shultz LD, Nishikawa S 1990 The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345:442
97. Felix R, Cecchini MG, Hofstetter W, Elford PR, Stutzer A, Fleisch H 1990 Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse. J Bone Miner Res 5:781
98. Felix R, Cecchini MG, Fleisch H 1990 Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology 127:2592
99. Kodama H, Yamasaki A, Nose M, Niida S, Ohgame Y, Abe M, Kumegawa M, Suda T 1991 Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor. J Exp Med 173:269
100. Takahashi N, Udagawa N, Akatsu T, Tanaka H, Isogai Y, Suda T 1991 Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells. Endocrinology 128:1792
101. Hattersley G, Owens J, Flanagan AM, Chambers TJ 1991 Macrophage colony stimulating factor (M-CSF) is essential for osteoclast formation In vitro. Biochem Biophys Res Commun 177:526
102. Kodama H, Nose M, Niida S, Yamasaki A 1991 Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells. J Exp Med 173:1291
103. Hattersley G, Dorey E, Horton MA, Chambers TJ 1988 Human macrophage colony-stimulating factor inhibits bone resorption by osteoclasts disaggregated from rat bone. J Cell Physiol 137:199
104. Takahashi N, Udagawa N, Akatsu T, Tanaka H, Shionome M, Suda T 1991 Role of colony-stimulating factors in osteoclast development. J Bone Miner Res 6:977
105. d mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am J Pathol 127:191
106. Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A 1988 The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature 335:88
107. Witte ON 1990 Steel locus defines new multipotent growth factor. Cell 63:5
108. Sherr CJ, Rettenmier CW, Sacca R, Roussel MF, Look AT, Stanley ER 1985 The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 41:665
109. Ebi Y, Kasugai T, Seino Y, Onoue H, Kanemoto T, Kitamura Y 1990 Mechanism of mast cell deficiency in mutant mice of mi/mi genotype: an analysis by co-culture of mast cells and fibroblasts. Blood 75:1247
110. Dubreuil P, Forrester L, Rottapel R, Reedijk M, Fujita J, Bernstein A 1991 The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice. Proc Natl Acad Sci USA 88:2341
111. Soriano P, Montgomery C, Geske R, Bradley A 1991 Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:693
112. Kato I, Yoneda T, Izbicka E, Lee C, Gutierrez G, Boyce B, Soriano P, Mundy GR 1991 Osteoclasts deficient in c-src tyrosine kinase fail to resorb bone in vitro and in vivo. J Bone Miner Res 6 [Suppl. 1]:197 (Abstract)