Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings

Journal of the American Geriatrics Society

Volumn 65, Issue 1, 2017, Pages e6-e12

  Browndyke, Jeffrey N ^a,b,c   Berger, Miles ^a   Harshbarger, Todd B ^a,c   Smith, Patrick J ^a   White, William ^a   Bisanar, Tiffany L ^a   Alexander, John H ^a   Gaca, Jeffrey G ^a   Welsh Bohmer, Kathleen ^a   Newman, Mark F ^a   Mathew, Joseph P ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

anesthesia; brain; cardiac surgical procedures; cognition; functional neuroimaging

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GERIATRIC SURGERY; HEART SURGERY; HEART VALVE REPLACEMENT; HUMAN; MAJOR SURGERY; MALE; NUCLEAR MAGNETIC RESONANCE SCANNER; PERIOPERATIVE PERIOD; POSTERIOR CINGULATE; POSTOPERATIVE COGNITIVE DYSFUNCTION; PROSPECTIVE STUDY; RESTING STATE NETWORK; SUPERIOR FRONTAL GYRUS; WHITE MATTER; WHITE MATTER LESION; ADVERSE EFFECTS; BRAIN; CARDIOVASCULAR SURGERY; CASE CONTROL STUDY; COGNITIVE DYSFUNCTION; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; POSTOPERATIVE COMPLICATIONS; REST; UNIVERSITY HOSPITAL;

ACADEMIC MEDICAL CENTERS; AGED; BRAIN; CARDIOVASCULAR SURGICAL PROCEDURES; CASE-CONTROL STUDIES; COGNITIVE DYSFUNCTION; FEMALE; FUNCTIONAL NEUROIMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; POSTOPERATIVE COMPLICATIONS; REST;

EID: 85002685583     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.14534     Document Type: Article

References (28)

1. Berger M, Nadler JW, Browndyke J et al. Postoperative cognitive dysfunction: Minding the gaps in our knowledge of a common postoperative complication in the elderly. Anesthesiol Clin 2015;33:517–550.
2. Terrando N, Monaco C, Ma D et al. Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline. Proc Natl Acad Sci U S A 2010;107:20518–20522.
3. Xu Z, Dong Y, Wang H et al. Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice. Sci Rep 2014;4:3766.
4. Tang JX, Mardini F, Janik LS et al. Modulation of murine Alzheimer pathogenesis and behavior by surgery. Ann Surg 2013;257:439–448.
5. Selnes OA, McKhann GM, Borowicz LM Jr et al. Cognitive and neurobehavioral dysfunction after cardiac bypass procedures. Neurolog Clin 2006;24:133–145.
6. Feng X, Degos V, Koch LG et al. Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome. Anesthesiology 2013;118:1098–1105.
7. Damoiseaux JS, Rombouts SA, Barkhof F et al. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A 2006;103:13848–13853.
8. Raichle ME. The brain's default mode network. Annu Rev Neurosci 2015;38:433–447.
9. van den Heuvel MP, Sporns O. An anatomical substrate for integration among functional networks in human cortex. J Neurosci 2013;33:14489–14500.
10. Sala-Llonch R, Bartres-Faz D, Junque C. Reorganization of brain networks in aging: A review of functional connectivity studies. Front Psychol 2015;6:663.
11. Dennis EL, Thompson PM. Functional brain connectivity using fMRI in aging and Alzheimer's disease. Neuropsychol Rev 2014;24:49–62.
12. Choi SH, Lee H, Chung TS et al. Neural network functional connectivity during and after an episode of delirium. Am J Psychiatry 2012;169:498–507.
13. Inouye SK, van Dyck CH, Alessi CA et al. Clarifying confusion: The Confusion Assessment Method. A new method for detection of delirium. Ann Intern Med 1990;113:941–948.
14. Voyvodic JT, Glover GH, Greve D et al. Automated real-time behavioral and physiological data acquisition and display integrated with stimulus presentation for fMRI. Front Neuroinform 2011;5:27.
15. Behzadi Y, Restom K, Liau J et al. A component based noise correction method (CompCor) for BOLD and perfusion based fMRI. NeuroImage 2007;37:90–101.
16. Duff K. Evidence-based indicators of neuropsychological change in the individual patient: Relevant concepts and methods. Arch Clin Neuropsychol 2012;27:248–261.
17. Silbert B, Evered L, Scott DA et al. Preexisting cognitive impairment is associated with postoperative cognitive dysfunction after hip joint replacement surgery. Anesthesiology 2015;122:1224–1234.
18. Constable RT, Vohr BR, Scheinost D et al. A left cerebellar pathway mediates language in prematurely-born young adults. NeuroImage 2013;64:371–378.
19. Martuzzi R, Ramani R, Qiu M et al. A whole-brain voxel based measure of intrinsic connectivity contrast reveals local changes in tissue connectivity with anesthetic without a priori assumptions on thresholds or regions of interest. NeuroImage 2011;58:1044–1050.
20. Woo CW, Krishnan A, Wager TD. Cluster-extent based thresholding in fMRI analyses: Pitfalls and recommendations. NeuroImage 2014;91:412–419.
21. Patel N, Horsfield MA, Banahan C et al. Impact of perioperative infarcts after cardiac surgery. Stroke 2015;46:680–686.
22. Scott DA, Evered LA, Gerraty RP et al. Cognitive dysfunction follows left heart catheterisation but is not related to microembolic count. Int J Cardiol 2014;175:67–71.
23. Leech R, Sharp DJ. The role of the posterior cingulate cortex in cognition and disease. Brain 2014;137:12–32.
24. Jacobs B, Schall M, Prather M et al. Regional dendritic and spine variation in human cerebral cortex: A quantitative Golgi study. Cereb Cortex 2001;11:558–571.
25. Collin G, Sporns O, Mandl RC et al. Structural and functional aspects relating to cost and benefit of rich club organization in the human cerebral cortex. Cereb Cortex 2014;24:2258–2267.
26. Achard S, Salvador R, Whitcher B et al. A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. J Neurosci 2006;26:63–72.
27. Raichle ME, MacLeod AM, Snyder AZ et al. A default mode of brain function. Proc Natl Acad Sci U S A 2001;98:676–682.
28. Schwarz N, Kastaun S, Schoenburg M et al. Subjective impairment after cardiac surgeries: The relevance of postoperative cognitive decline in daily living. Eur J Cardiothorac Surg 2013;43:e162–e166.