Successful treatment of cytomegalovirus associated hemophagocytic lymphohistiocytosis with the interleukin 1 inhibitor - anakinra

Respirology Case Reports

Volumn 4, Issue 1, 2016, Pages 4-6

  Divithotawela, Chandima ^a   Garrett, Peter ^b   Westall, Glen ^c   Bhaskar, Balu ^a   Tol, Maneesha ^a   Chambers, Daniel C ^a  

^a THE PRINCE CHARLES HOSPITAL   (Australia)

^b Noosa Hospital   (Australia)

^c ALFRED HOSPITAL   (Australia)

Author keywords

Hemophagocytic lymphohistiocytosis; Inflammation; Pulmonary; Virology

Indexed keywords

EID: 85002245089     PISSN: None     EISSN: 20513380     Source Type: Journal    
DOI: 10.1002/rcr2.137     Document Type: Article

References (5)

1. Wijsman CA, Roeters van Lennep JE, von dem Borne PA, et al. 2009. A diagnostic difficulty: two cases of haemophagocytic syndrome in adults. Neth. J. Med. 67(1):29-31.
2. Kullmann T, Kárász T, Gartner B, et al. 2013. Acute cytomegalovirus infection-associated hemophagocytic syndrome in a patient treated with azathioprine [in Hungarian]. Orv. Hetil. 154(49):1959-1961.
3. Henter JI, Horne A, Aricó M, et al. 2007. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr. Blood Cancer 48(2):124-131.
4. Rajasekaran S, Kruse K, Kovey K, et al. 2014. Therapeutic role of anakinra, an interleukin-1 receptor antagonist, in the management of secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction/macrophage activating syndrome in critically ill children. Pediatr. Crit. Care Med. 15(5):401-408.
5. Miettunen PM, Narendran A, Jayanthan A, et al. 2011. Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients. Rheumatology (Oxford) 50(2):417-419.