Relationship between upper respiratory tract influenza test result and clinical outcomes among critically ill influenza patients

Open Forum Infectious Diseases

Volumn 3, Issue 1, 2016, Pages

  Reddy, Krishna P ^a,b,f,g   Bajwa, Ednan K ^b,g   Parker, Robert A ^a,c,d,g   Onderdonk, Andrew B ^e,g   Walensky, Rochelle P ^a,c,d,e,g  

^a Medical Practice Evaluation Center   (United States)

^b Division of Pulmonary and Critical Care Medicine   (United States)

^c Division of General Internal Medicine   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Critically ill; Influenza diagnosis; Lower respiratory tract; Upper respiratory tract

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; HUMAN; IMMUNOFLUORESCENCE; INFLUENZA; LUNG LAVAGE; MAJOR CLINICAL STUDY; NOSE SMEAR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPUTUM EXAMINATION; TRACHEAL ASPIRATION PROCEDURE; UPPER RESPIRATORY TRACT INFECTION;

EID: 85000365254     PISSN: None     EISSN: 23288957     Source Type: Journal    
DOI: 10.1093/ofid/ofw023     Document Type: Article

References (13)

1. Ortiz JR, Neuzil KM, Shay DK, et al. The burden of influenza-associated critical illness hospitalizations. Crit Care Med 2014; 42:2325-32.
2. Lynfield R, Davey R, Dwyer DE, et al. Outcomes of influenza A(H1N1)pdm09 virus infection: results from two international cohort studies. PLoS One 2014; 9:e101785.
3. Nin N, Soto L, Hurtado J, et al. Clinical characteristics and outcomes of patients with 2009 influenza A(H1N1) virus infection with respiratory failure requiring mechanical ventilation. J Crit Care 2011; 26:186-92.
4. Blyth CC, Iredell JR, Dwyer DE. Rapid-test sensitivity for novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 361:2493.
5. Rice TW, Rubinson L, Uyeki TM, et al. Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States. Crit Care Med 2012; 40:1487-98.
6. López Roa P, Rodríguez-Sánchez B, Catalán P, et al. Diagnosis of influenza in intensive care units: lower respiratory tract samples are better than nose-throat swabs. Am J Respir Crit Care Med 2012; 186:929-30.
7. Kuiken T, Taubenberger JK. Pathology of human influenza revisited. Vaccine 2008; 26:D59-66.
8. Lee N, Chan PK, Wong CK, et al. Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumonia. Antivir Ther 2011; 16:237-47.
9. Hui DS, Lee N, Chan PK. Clinical management of pandemic 2009 influenza A(H1N1) infection. Chest 2010; 137:916-25.
10. Yeh E, Luo RF, Dyner L, et al. Preferential lower respiratory tract infection in swine-origin 2009 A(H1N1) influenza. Clin Infect Dis 2010; 50:391-4.
11. Piralla A, Pariani E, Rovida F, et al. Segregation of virulent influenza A(H1N1) variants in the lower respiratory tract of critically ill patients during the 2010-2011 seasonal epidemic. PLoS One 2011; 6:e28332.
12. Munster VJ, de Wit E, van den Brand JM, et al. Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science 2009; 325:481-3.
13. Chen W, Ayala E, Hill S, et al. Diagnosis of 2009 influenza A H1N1: diagnostic utility of blind endotracheal aspirate in intubated patients with false negative real-time reverse transcriptase polymerase chain reaction assays from nasopharyngeal samples. American Thoracic Society, 2010: A2623. Available at: http://dx.doi. org/10.1164/ajrccm-conference.2010.181.1_MeetingAbstracts.A2623. Accessed 28 January 2016.