Duration of infant protection against influenza illness conferred by maternal immunization secondary analysis of a randomized clinical trial

JAMA Pediatrics

Volumn 170, Issue 9, 2016, Pages 840-847

  Nunes, Marta C ^a   Cutland, Clare L ^a   Jones, Stephanie ^a   Hugo, Andrea ^a   Madimabe, Richard ^a   Simões, Eric A F ^a,b   Weinberg, Adriana ^c   Madhi, Shabir A ^a,d  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b University of Colorado Denver and Children s Hospital Colorado   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTINATION INHIBITING ANTIBODY; INFLUENZA VACCINE;

ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG SAFETY; FEMALE; FOLLOW UP; GESTATIONAL AGE; HUMAN; IMMUNOGENICITY; INFECTION PREVENTION; INFLUENZA; INFLUENZA VACCINATION; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; PASSIVE IMMUNIZATION; POLYMERASE CHAIN REACTION; PREGNANT WOMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SECOND TRIMESTER PREGNANCY; SECONDARY ANALYSIS; THIRD TRIMESTER PREGNANCY; TREATMENT DURATION; ADULT; FETOMATERNAL TRANSFUSION; IMMUNOLOGY; INFLUENZA, HUMAN; NEWBORN; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY OUTCOME; SOUTH AFRICA;

ADULT; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT, NEWBORN; INFLUENZA VACCINES; INFLUENZA, HUMAN; MALE; MATERNAL-FETAL EXCHANGE; PLACENTA; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY OUTCOME; SOUTH AFRICA;

EID: 84998886302     PISSN: 21686203     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapediatrics.2016.0921     Document Type: Article

References (25)

1. Izurieta HS, Thompson WW, Kramarz P, et al. Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med. 2000;342(4):232-239.
2. Neuzil KM, Mellen BG, Wright PF, Mitchel EF Jr, Griffin MR. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med. 2000;342(4): 225-231.
3. Poehling KA, Edwards KM, Weinberg GA, et al; New Vaccine Surveillance Network. The underrecognized burden of influenza in young children. N Engl J Med. 2006;355(1):31-40.
4. Poehling KA, Edwards KM, Griffin MR, et al. The burden of influenza in young children, 2004-2009. Pediatrics. 2013;131(2):207-216.
5. Bhat N, Wright JG, Broder KR, et al; Influenza Special Investigations Team. Influenza-Associated deaths among children in the United States, 2003-2004. N Engl J Med. 2005;353(24):2559-2567.
6. Cohen C, Moyes J, Tempia S, et al. Mortality amongst patients with influenza-Associated severe acute respiratory illness, South Africa, 2009-2013. PLoS One. 2015;10(3):e0118884.
7. Jones C, Heath P. Antenatal immunization. Hum Vaccin Immunother. 2014;10(7):2118-2122.
8. Madhi SA, Cutland CL, Kuwanda L, et al; Maternal Flu Trial (Matflu) Team. Influenza vaccination of pregnant women and protection of their infants. N Engl J Med. 2014;371(10):918-931.
9. Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal influenza immunization in mothers and infants [published correction appears in N Engl J Med. 2009;360(6):648].
10. N Engl J Med. 2008;359 (15):1555-1564.
11. Nunes MC, Cutland CL, Dighero B, et al; Matflu Team. Kinetics of hemagglutination-inhibiting antibodies following maternal influenza vaccination among mothers with and those without HIV infection and their infants. J Infect Dis. 2015;212(12): 1976-1987.
12. Word Health Organization. Recommended viruses for influenza vaccines for use in the 2011 southern hemisphere influenza season. http://www .who.int/influenza/vaccines/virus/2011south/en/. Published September 2010. Accessed June 2, 2016.
13. Vaxigrip [package insert]. Lyon, France: Sanofi Pasteur; 2011.
14. Weinberg A, Song LY, Walker R, et al; IMPAACT P1057 Team. Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children. J Acquir Immune Defic Syndr. 2010;55(2):189-196.
15. Influenza Reagent Resource. Atlanta, GA: Centers for Disease Control and Prevention. https://www.influenzareagentresource.org. Accessed June 2, 2016.
16. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377-381.
17. Respiratory virus surveillance report, South Africa. National Institute for Communicable Diseases: A division of National Health Laboratory Service. http://www.nicd.ac.za/assets/files/CommDisBull%2010(2)-May%20final2012.pdf. Accessed June 7, 2016.
18. Maltezou HC, Fotiou A, Antonakopoulos N, et al. Impact of postpartum influenza vaccination of mothers and household contacts in preventing febrile episodes, influenza-like illness, healthcare seeking, and administration of antibiotics in young infants during the 2012-2013 influenza season. Clin Infect Dis. 2013;57(11):1520-1526.
19. Schlaudecker EP, Steinhoff MC, Omer SB, et al. IgA and neutralizing antibodies to influenza a virus in human milk: A randomized trial of antenatal influenza immunization. PLoS One. 2013;8(8): e70867.
20. Englund JA. The influence of maternal immunization on infant immune responses. J Comp Pathol. 2007;137(suppl 1):S16-S19.
21. Steinhoff MC, Omer SB, Roy E, et al. Influenza immunization in pregnancy-Antibody responses in mothers and infants. N Engl J Med. 2010;362(17): 1644-1646.
22. Hobson D, Curry RL, Beare AS, Ward-Gardner A. The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses. J Hyg (Lond). 1972; 70(4):767-777.
23. Black S, Nicolay U, Vesikari T, et al. Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children. Pediatr Infect Dis J. 2011;30 (12):1081-1085.
24. Jackson LA, Patel SM, Swamy GK, et al. Immunogenicity of an inactivated monovalent 2009 H1N1 influenza vaccine in pregnant women. J Infect Dis. 2011;204(6):854-863.
25. Blanchard-Rohner G, Meier S, Bel M, et al. Influenza vaccination given at least 2 weeks before delivery to pregnant women facilitates transmission of seroprotective influenza-specific antibodies to the newborn. Pediatr Infect Dis J. 2013;32(12): 1374-1380.