Suppression of immunotherapy on group 2 Innate lymphoid cells in allergic rhinitis

Chinese Medical Journal

Volumn 129, Issue 23, 2016, Pages 2824-2828

  Fan, Da Chuan ^a,b   Wang, Xiang Dong ^c   Wang, Cheng Shuo ^a,c   Wang, Yang ^c   Cao, Fei Fei ^a   Zhang, Luo ^a,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE OF OTOLARYNGOLOGY   (China)

Author keywords

Allergic rhinitis; Group 2 innate lymphoid cell; House dust mite; Immunotherapy

Indexed keywords

CD14 ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; CD34 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN E; T LYMPHOCYTE RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 5;

ADULT; ALLERGIC RHINITIS; ARTICLE; ASTHMA; CELL COUNT; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNE RESPONSE; LYMPHOID CELL; MALE; MIDDLE AGED; NASAL PRURITUS; NOSE OBSTRUCTION; OCULAR PRURITUS; PRICK TEST; RHINORRHEA; SENSITIVITY ANALYSIS; SNEEZING; SUBCUTANEOUS IMMUNOTHERAPY; ADOLESCENT; ANIMAL; IMMUNOLOGY; LYMPHOCYTE; METABOLISM; RHINITIS, ALLERGIC; SKIN TEST; SUBLINGUAL IMMUNOTHERAPY; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; DERMATOPHAGOIDES PTERONYSSINUS; FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-13; INTERLEUKIN-5; LYMPHOCYTES; MALE; RHINITIS, ALLERGIC; SKIN TESTS; SUBLINGUAL IMMUNOTHERAPY; YOUNG ADULT;

EID: 84998828016     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.4103/0366-6999.194642     Document Type: Article

References (22)

1. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2) LEN and AllerGen). Allergy 2008;63 Suppl 86:8-160. doi:10.1111/j.1398-9995.2007.01620.x.
2. Zhang Y, Zhang L. Prevalence of allergic rhinitis in china. Allergy Asthma Immunol Res 2014;6:105-13. doi:10.4168/aair.2014.6.2.105.
3. Li J, Sun B, Huang Y, Lin X, Zhao D, Tan G, et al. A multicentre study assessing the prevalence of sensitizations in patients with asthma and/ or rhinitis in China. Allergy 2009;64:1083-92. doi:10.1111/j.1398-9995.2009.01967.x.
4. Shaaban R, Zureik M, Soussan D, Neukirch C, Heinrich J, Sunyer J, et al. Rhinitis and onset of asthma: A longitudinal population-based study. Lancet 2008;372:1049-57. doi:10.1016/S0140-6736(08)61446-4.
5. Lou W, Wang C, Wang Y, Han D, Zhang L. Enhancement of the frequency and function of IL-10-secreting type I T regulatory cells after 1 year of cluster allergen-specific immunotherapy. Int Arch Allergy Immunol 2012;159:391-8. doi:10.1159/000338995.
6. Lou W, Wang C, Wang Y, Han D, Zhang L. Responses of CD4(+) CD25(+) Foxp3(+) and IL-10-secreting type I T regulatory cells to cluster-specific immunotherapy for allergic rhinitis in children. Pediatr Allergy Immunol 2012;23:140-9. doi:10.1111/j.1399-3038.2011.01249.x.
7. Jutel M, Akdis CA. Immunological mechanisms of allergen-specific immunotherapy. Allergy 2011;66:725-32. doi:10.1111/j.1398-9995.2011.02589.x.
8. Doherty TA, Scott D, Walford HH, Khorram N, Lund S, Baum R, et al. Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84. J Allergy Clin Immunol 2014;133:1203-5. doi:10.1016/j.jaci.2013.12.1086.
9. Lao-Araya M, Steveling E, Scadding GW, Durham SR, Shamji MH. Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy. J Allergy Clin Immunol 2014;134:1193-5.e4. doi:10.1016/j.jaci.2014.07.029.
10. Salimi M, Barlow JL, Saunders SP, Xue L, Gutowska-Owsiak D, Wang X, et al. A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med 2013;210:2939-50. doi:10.1084/jem.20130351.
11. Bartemes KR, Kephart GM, Fox SJ, Kita H. Enhanced innate type 2 immune response in peripheral blood from patients with asthma. J Allergy Clin Immunol 2014;134:671-8.e4. doi:10.1016/j.jaci.2014.06.024.
12. Moro K, Yamada T, Tanabe M, Takeuchi T, Ikawa T, Kawamoto H, et al. Innate production of T(H) 2 cytokines by adipose tissue-associated c-Kit(+) Sca-1(+) lymphoid cells. Nature 2010;463:540-4. doi:10.1038/nature08636.
13. Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010;464:1367-70. doi:10.1038/nature08900.
14. Price AE, Liang HE, Sullivan BM, Reinhardt RL, Eisley CJ, Erle DJ, et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci U S A 2010;107:11489-94. doi:10.1073/pnas.1003988107.
15. Zhang L, Wang C, Han D, Wang X, Zhao Y, Liu J. Comparative study of cluster and conventional immunotherapy schedules with Dermatophagoides pteronyssinus in the treatment of persistent allergic rhinitis. Int Arch Allergy Immunol 2009;148:161-9. doi:10.1159/000155747.
16. Mjösberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, et al. Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol 2011;12:1055-62. doi:10.1038/ni.2104.
17. Nawijn MC, Hackett TL, Postma DS, van Oosterhout AJ, Heijink IH. E-cadherin: Gatekeeper of airway mucosa and allergic sensitization. Trends Immunol 2011;32:248-55. doi:10.1016/j.it.2011.03.004.
18. Banh C, Fugère C, Brossay L. Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling. Blood 2009;114:5299-306. doi:10.1182/blood-2009-06-228353.
19. Kobayashi N, Terada N, Hamano N, Numata T, Konno A. Transepithelial migration of activated eosinophils induces a decrease of E-cadherin expression in cultured human nasal epithelial cells. Clin Exp Allergy 2000;30:807-17. doi:10.1046/j.1365-2222.2000.00827.x.
20. Kobayashi N, Dezawa M, Nagata H, Yuasa S, Konno A. Immunohistochemical study of E-cadherin and ZO-1 in allergic nasal epithelium of the guinea pig. Int Arch Allergy Immunol 1998;116:196-205. doi:10.1159/000023945.
21. Sun X, Yang H, Nose K, Nose S, Haxhija EQ, Koga H, et al. Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 2008;294:G139-47. doi:10.1152/ajpgi.00386.2007.
22. Cosmi L, Santarlasci V, Angeli R, Liotta F, Maggi L, Frosali F, et al. Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin E and increases both interferon-gamma- and interleukin-10-production. Clin Exp Allergy 2006;36:261-72. doi:10.1111/j.1365-2222.2006.02429.x.