CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

Oncotarget

Volumn 7, Issue 46, 2016, Pages 75130-75144

  Komdeur, Fenne L ^a   Wouters, Maartje C A ^a   Workel, Hagma H ^a   Tijans, Aline M ^a   Terwindt, Anouk L J ^a   Brunekreeft, Kim L ^a   Plat, Annechien ^a   Klip, Harry G ^a   Eggink, Florine A ^a   Leffers, Ninke ^a   Helfrich, Wijnand ^a   Samplonius, Douwe F ^a   Bremer, Edwin ^a   Wisman, G Bea A ^a   Daemen, Toos ^a   Duiker, Evelien W ^a   Hollema, Harry ^a   Nijman, Hans W ^a   de Bruyn, Marco ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cancer immunotherapy; CD103; High grade serous ovarian cancer; TGF ; Tumor infiltrating lymphocytes

Indexed keywords

CD103 ANTIGEN; CD27 ANTIGEN; CD3 ANTIGEN; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; ALPHA E INTEGRINS; ALPHA INTEGRIN; BIOLOGICAL MARKER; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PDCD1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; ARTICLE; CANCER EPITHELIUM; CANCER IMMUNOTHERAPY; CANCER PROGNOSIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPITHELIUM; FEMALE; GENETIC ASSOCIATION; HIGH GRADE SEROUS OVARY CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE DIFFERENTIATION; MAJOR CLINICAL STUDY; MEMORY T LYMPHOCYTE; OVARY CANCER; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TUMOR ASSOCIATED LEUKOCYTE; ADOPTIVE IMMUNOTHERAPY; CANCER GRADING; IMMUNOLOGY; IMMUNOTHERAPY; INTRAEPITHELIAL LYMPHOCYTE; METABOLISM; OVARY TUMOR; PATHOLOGY; PROGNOSIS;

ANTIGENS, CD; BIOMARKERS; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; IMMUNOTHERAPY; IMMUNOTHERAPY, ADOPTIVE; INTEGRIN ALPHA CHAINS; INTRAEPITHELIAL LYMPHOCYTES; LYMPHOCYTES, TUMOR-INFILTRATING; NEOPLASM GRADING; OVARIAN NEOPLASMS; PHENOTYPE; PROGNOSIS; PROGRAMMED CELL DEATH 1 RECEPTOR; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 7;

EID: 84996805838     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.12077     Document Type: Article

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