Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial

The Lancet Gastroenterology and Hepatology

Volumn 1, Issue 1, 2016, Pages 15-24

  Williams, John G ^a   Alam, M Fasih ^b   Alrubaiy, Laith ^a   Arnott, Ian ^c   Clement, Clare ^a   Cohen, David ^d   Gordon, John N ^e   Hawthorne, A Barney ^f   Hilton, Mike ^a   Hutchings, Hayley A ^a   Jawhari, Aida U ^g   Longo, Mirella ^b   Mansfield, John ^h   Morgan, Jayne M ^a   Rapport, Frances ^a   Seagrove, Anne C ^a   Sebastian, Shaji ⁱ   Shaw, Ian ^j   Travis, Simon P L ^k   Watkins, Alan ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF GLAMORGAN   (United Kingdom)

^e ROYAL HAMPSHIRE COUNTY HOSPITAL   (United Kingdom)

^f UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^g NIHR NOTTINGHAM BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

^h ROYAL VICTORIA INFIRMARY   (United Kingdom)

ⁱ HULL AND EAST YORKSHIRE HOSPITALS NHS TRUST   (United Kingdom)

^j GLOUCESTERSHIRE HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^k OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; INFLIXIMAB; CYCLOSPORINE; HYDROCORTISONE; IMMUNOSUPPRESSIVE AGENT;

ACUTE SEVERE ULCERATIVE COLITIS; ADULT; ALLERGY; AREA UNDER THE CURVE; ARTICLE; BASAL CELL CARCINOMA; CHEST INFECTION; CLOSTRIDIUM DIFFICILE INFECTION; COLON RESECTION; COLORECTAL CANCER; CONTINUOUS INFUSION; CONTROLLED STUDY; CROHNS AND ULCERATIVE COLITIS QUESTIONNAIRE; DEATH; DRUG EFFICACY; DRUG SAFETY; ENDOMETRIUM CANCER; FEMALE; GASTROINTESTINAL DISEASE; HUMAN; KIDNEY DISEASE; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MULTICENTER STUDY; NEUROLOGIC DISEASE; OPEN STUDY; PARALLEL DESIGN; PRIORITY JOURNAL; QUALITY OF LIFE ASSESSMENT; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SKIN CARCINOMA; SKIN INFECTION; SURGICAL INFECTION; ULCERATIVE COLITIS; ADOLESCENT; AGED; CLINICAL TRIAL; COMPARATIVE STUDY; COST BENEFIT ANALYSIS; DRUG ADMINISTRATION; ECONOMICS; FOLLOW UP; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; UNITED KINGDOM; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; COLITIS, ULCERATIVE; COST-BENEFIT ANALYSIS; CYCLOSPORINE; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYDROCORTISONE; IMMUNOSUPPRESSIVE AGENTS; INFLIXIMAB; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; UNITED KINGDOM; YOUNG ADULT;

EID: 84995899350     PISSN: 24681253     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2468-1253(16)30003-6     Document Type: Article

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