New therapeutic strategies for BRAF mutant colorectal cancers

Journal of Gastrointestinal Oncology

Volumn 6, Issue 6, 2015, Pages 650-659

  Corcoran, Ryan B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

BRAF; BRAF inhibitor; Clinical trials; Colorectal cancer(CRC)

Indexed keywords

ALPELISIB; B RAF KINASE INHIBITOR; CETUXIMAB; DABRAFENIB; ENCORAFENIB; EPIDERMAL GROWTH FACTOR RECEPTOR; IRINOTECAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PANITUMUMAB; PROGRAMMED DEATH 1 LIGAND 1; TRAMETINIB; VEMURAFENIB;

ANTINEOPLASTIC ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CLINICAL TRIAL (TOPIC); COLORECTAL CANCER; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; MELANOMA; OVERALL SURVIVAL; PILOT STUDY; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; TUMOR REGRESSION;

EID: 84995790097     PISSN: 20786891     EISSN: 2219679X     Source Type: Journal    
DOI: 10.3978/j.issn.2078-6891.2015.076     Document Type: Review

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