Correlates of immunity to influenza as determined by challenge of children with live, attenuated influenza vaccine

Open Forum Infectious Diseases

Volumn 3, Issue 2, 2016, Pages

  Wright, Peter F ^a   Hoen, Anne G ^a   Ilyushina, Natalia A ^a,f   Brown, Eric P ^b   Ackerman, Margaret E ^b   Wieland Alter, Wendy ^a   Connor, Ruth I ^a   Jegaskanda, Sinthujan ^c   Rosenberg Hasson, Yael ^d   Haynes, Brenda C ^a   Luke, Catherine J ^c   Subbarao, Kanta ^c   Treanor, John J ^e  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH COLLEGE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d STANFORD UNIVERSITY   (United States)

^e UNIVERSITY OF ROCHESTER   (United States)

^f CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Humoral immunity; Influenza vaccine; Mucosal immunity; Vaccine

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INACTIVATED VIRUS VACCINE; INFLUENZA VACCINE; NEUTRALIZING ANTIBODY;

ANTIBODY BLOOD LEVEL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CELLULAR IMMUNITY; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATIONAL STUDY; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMAGGLUTINATION INHIBITION; HUMAN; IMMUNE RESPONSE; INFLUENZA VACCINATION; MUCOSAL IMMUNITY; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROVOCATION TEST; VIRUS NEUTRALIZATION; VIRUS SHEDDING;

EID: 84995639400     PISSN: None     EISSN: 23288957     Source Type: Journal    
DOI: 10.1093/ofid/ofw108     Document Type: Article

References (25)

1. Johnson PR, Feldman S, Thompson JM, et al. Immunity to influenza A virus infection in young children: a comparison of natural infection, live cold-adapted vaccine, and inactivated vaccine. J Infect Dis 1986; 154:121-7.
2. Mohammed AJ, AlAwaidy S, Bawikar S, et al. Fractional doses of inactivated poliovirus vaccine in Oman. N Engl J Med 2010; 362:2351-9.
3. Wright PF, Wieland-Alter W, Ilyushina NA, et al. Intestinal immunity is a determinant of clearance of poliovirus after oral vaccination. J Infect Dis 2014; 209:1628-34.
4. Ilyushina NA, Haynes BC, Hoen AG, et al. Live attenuated and inactivated influenza vaccines in children. J Infect Dis 2015; 211:352-60.
5. Wright PF, Bhargava M, Johnson PR, et al. Simultaneous administration of live, attenuated influenza A vaccines representing different serotypes. Vaccine 1985; 3:305-8.
6. Jegaskanda S, Job ER, KramskiM, et al. Cross-reactive influenza-specific antibodydependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies. J Immunol 2013; 190:1837-48.
7. Rosenberg-Hasson Y, Hansmann L, Liedtke M, et al. Effects of serum and plasma matrices on multiplex immunoassays. Immunol Res 2014; 58:224-33.
8. Marshall HD, Ray JP, Laidlaw BJ, et al. The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa. Elife 2015; 8:4.
9. Wu Z, Hao R, Li P, et al. MicroRNA expression profile of mouse lung infected with 2009 pandemic H1N1 influenza virus. PLoS One 2013; 8:e74190.
10. Yu CI, Becker C, Wang Y, et al. CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β. Immunity 2013; 38:818-30.
11. Fleet WF, Couch RB, Cate TR, Knight V. Homologous and heterologous resistance to rhinovirus common cold. Am J Epidemiol 1965; 82:185-96.
12. Oshansky CM, Gartland AJ, Wong SS, et al. Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load. Am J Respir Crit Care Med 2014; 89:449-62.
13. Clements ML, Betts RF, Tierney EL, Murphy BR. Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus. J Clin Microbiol 1986; 24:157-60.
14. Clements ML, Betts RF, Tierney EL, Murphy BR. Resistance of adults to challenge with influenza A wild-type virus after receiving live or inactivated virus vaccine. J Clin Microbiol 1986; 23:73-6.
15. Johnson PR Jr, Feldman S, Thompson JM, et al. Comparison of long-term systemic and secretory antibody responses in children given live, attenuated, or inactivated influenza A vaccine. J Med Virol 1985; 17:325-35.
16. Belshe RB, Mendelman PM, Treanor J, et al. The efficacy of live attenuated, coldadapted, trivalent, intranasal influenzavirus vaccine in children. N Engl J Med 1998; 338:1405-12.
17. Belshe RB, Edwards KM, Vesikari T, et al. Live attenuated versus inactivated influenza vaccine in infants and young children. N Engl J Med 2007; 356:685-96.
18. Committee on Infectious Diseases; American Academy Pediatrics. Recommendations for prevention and control of influenza in children, 2014-2015. Pediatrics 2014; 134:e1503-19.
19. Grohskopf LA, Olsen SJ, Sokolow LZ, et al. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP)-United States, 2014-15 influenza season. MMWR Morb Mortal Wkly Rep 2014; 63:691-7.
20. Chung JR, Flannery B, Thompson MG, et al. Seasonal effectiveness if live attenuated and inactivated influenza vaccine. Pediatrics 2016; 137:1-10.
21. Grohskopf LA, Sokolow LZ, Olsen SJ, et al. Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, United States, 2015-16 influenza season. MMWR Morb Mortal Wkly Rep 2015; 64:818-25.
22. Karron RA, Talaat K, Luke C, et al. Evaluation of two live attenuated cold-adapted H5N1 influenza virus vaccines in healthy adults. Vaccine 2009; 27:4953-60.
23. Babu TM, Levine M, Fitzgerald T, et al. Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine. Vaccine 2014; 32:6798-804.
24. Hoft DF, Babusis E, Worku S, et al. Live and inactivated influenza vaccines induce similar humoral responses, but only live vaccines induce diverse T-cell responses in young children. J Infect Dis 2011; 204:845-53.
25. Renegar KB, Small PA Jr, Boykins LG, Wright PF. Role of IgA versus IgG in the control of influenza viral infection in the murine respiratory tract. J Immunol 2004; 173:1978-86.