Risk Alleles Associated with Neovascularization in a Pachychoroid Phenotype

Ophthalmology

Volumn 123, Issue 12, 2016, Pages 2628-2630

  Dansingani, Kunal K ^a,b,c,d   Perlee, Lorah T ^e   Hamon, Sara ^e   Lee, May ^a,b   Shah, Vinnie P ^a,b   Spaide, Richard F ^a,b,f   Sorenson, John ^a,b,f   Klancnik, James M ^a,b,f   Yannuzzi, Lawrence A ^a,b,f   Barbazetto, Irene A ^a,b,f   Cooney, Michael J ^a,b,f   Engelbert, Michael ^a,b,f   Chen, Christine ^g   Hewitt, Alex W ^h   Freund, K Bailey ^a,b,f  

^a VITREOUS RETINA MACULA CONSULTANTS OF NEW YORK   (United States)

^b EAR AND THROAT HOSPITAL   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d MOORFIELDS EYE HOSPITAL   (United Kingdom)

^e REGENERON PHARMACEUTICALS INC   (United States)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g MONASH UNIVERSITY   (Australia)

^h UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; APOLIPOPROTEIN; ARMS2 PROTEIN, HUMAN; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 13B; CFHR4 PROTEIN, HUMAN; COMPLEMENT; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; COMPLEMENT FACTOR H, HUMAN; EYE PROTEIN; PROTEIN;

AGE RELATED MACULAR DEGENERATION; ALLELE; CASE CONTROL STUDY; CENTRAL SEROUS RETINOPATHY; CONFERENCE PAPER; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; HUMAN; MULTIMODAL IMAGING; PHENOTYPE; PRIORITY JOURNAL; QUALITY CONTROL; RETINA NEOVASCULARIZATION; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; CHOROID DISEASE; FEMALE; GENETICS; MALE; MIDDLE AGED; RISK FACTOR; SUBRETINAL NEOVASCULARIZATION; VERY ELDERLY; WET MACULAR DEGENERATION;

AGED; AGED, 80 AND OVER; APOLIPOPROTEINS; CASE-CONTROL STUDIES; CHOROID DISEASES; CHOROIDAL NEOVASCULARIZATION; COMPLEMENT C2; COMPLEMENT C3; COMPLEMENT FACTOR B; COMPLEMENT FACTOR H; COMPLEMENT SYSTEM PROTEINS; EYE PROTEINS; FACTOR XIII; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; RISK FACTORS; WET MACULAR DEGENERATION;

EID: 84995560993     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2016.06.060     Document Type: Article

References (5)

1. 1 Dansingani, K.K., Balaratnasingam, C., Klufas, M.A., et al. Optical coherence tomography angiography of shallow irregular pigment epithelial detachments in pachychoroid spectrum disease. Am J Ophthalmol 160 (2015), 1243–1254.e2.
2. 2 Pang, C.E., Freund, K.B., Pachychoroid neovasculopathy. Retina 35 (2015), 1–9.
3. 3 Sobrin, L., Ripke, S., Yu, Y., et al. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology 119 (2012), 1874–1885.
4. 4 Dansingani, K.K., Balaratnasingam, C., Naysan, J., Freund, K.B., En face imaging of pachychoroid spectrum disorders with swept-source optical coherence tomography. Retina 36 (2016), 499–516.
5. 5 Freund, K.B., Zweifel, S.A., Engelbert, M., Do we need a new classification for choroidal neovascularization in age-related macular degeneration?. Retina 30 (2010), 1333–1349.