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Volumn 2016, Issue AUG, 2016, Pages

Current status of ABL tyrosine kinase inhibitors stop studies for chronic myeloid leukemia

Author keywords

ABL tyrosine kinase inhibitor (TKI); Chronic myeloid leukemia (CML); Discontinuation; Stop

Indexed keywords

ABELSON KINASE; ABELSON KINASE INHIBITOR; BCR ABL PROTEIN; DASATINIB; ENZYME INHIBITOR; IMATINIB; NILOTINIB; UNCLASSIFIED DRUG;

EID: 84994877342     PISSN: None     EISSN: 23069759     Source Type: Journal    
DOI: 10.21037/sci.2016.07.08     Document Type: Review
Times cited : (14)

References (27)
  • 1
    • 85029353793 scopus 로고    scopus 로고
    • Relative survival in patients with chronic-phase chronic myeloid leukaemia in the tyrosine-kinase inhibitor era: Analysis of patient data from six prospective clinical trials
    • Sasaki K, Strom SS, O'Brien S, et al. Relative survival in patients with chronic-phase chronic myeloid leukaemia in the tyrosine-kinase inhibitor era: analysis of patient data from six prospective clinical trials. Lancet Haematol 2015;2:e186-93.
    • (2015) Lancet Haematol , vol.2 , pp. e186-e193
    • Sasaki, K.1    Strom, S.S.2    O'Brien, S.3
  • 2
    • 84861839077 scopus 로고    scopus 로고
    • Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy
    • Huang X, Cortes J, Kantarjian H. Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Cancer 2012;118:3123-7.
    • (2012) Cancer , vol.118 , pp. 3123-3127
    • Huang, X.1    Cortes, J.2    Kantarjian, H.3
  • 3
    • 33846023983 scopus 로고    scopus 로고
    • Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years
    • Rousselot P, Huguet F, Rea D, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years. Blood 2007;109:58-60.
    • (2007) Blood , vol.109 , pp. 58-60
    • Rousselot, P.1    Huguet, F.2    Rea, D.3
  • 4
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Réa D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 2010;11:1029-35.
    • (2010) Lancet Oncol , vol.11 , pp. 1029-1035
    • Mahon, F.X.1    Réa, D.2    Guilhot, J.3
  • 5
    • 84960941451 scopus 로고    scopus 로고
    • Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): A multicentre phase 2 trial
    • Imagawa J, Tanaka H, Okada M, et al. Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial. Lancet Haematol 2015;2:e528-35.
    • (2015) Lancet Haematol , vol.2 , pp. e528-e535
    • Imagawa, J.1    Tanaka, H.2    Okada, M.3
  • 6
    • 84886917643 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: Results from the TWISTER study
    • Ross DM, Branford S, Seymour JF, et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood 2013;122:515-22.
    • (2013) Blood , vol.122 , pp. 515-522
    • Ross, D.M.1    Branford, S.2    Seymour, J.F.3
  • 7
    • 84897573995 scopus 로고    scopus 로고
    • Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease
    • Rousselot P, Charbonnier A, Cony-Makhoul P, et al. Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease. J Clin Oncol 2014;32:424-30.
    • (2014) J Clin Oncol , vol.32 , pp. 424-430
    • Rousselot, P.1    Charbonnier, A.2    Cony-Makhoul, P.3
  • 8
    • 84942194839 scopus 로고    scopus 로고
    • Age and dPCR can predict relapse in CML patients who discontinued imatinib: The ISAV study
    • Mori S, Vagge E, le Coutre P, et al. Age and dPCR can predict relapse in CML patients who discontinued imatinib: the ISAV study. Am J Hematol 2015;90:910-4.
    • (2015) Am J Hematol , vol.90 , pp. 910-914
    • Mori, S.1    Vagge, E.2    Le Coutre, P.3
  • 9
    • 84862136806 scopus 로고    scopus 로고
    • Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia
    • Takahashi N, Kyo T, Maeda Y, et al. Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia. Haematologica 2012;97:903-6.
    • (2012) Haematologica , vol.97 , pp. 903-906
    • Takahashi, N.1    Kyo, T.2    Maeda, Y.3
  • 10
    • 77958012952 scopus 로고    scopus 로고
    • Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR
    • Ross DM, Branford S, Seymour JF, et al. Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR. Leukemia 2010;24:1719-24.
    • (2010) Leukemia , vol.24 , pp. 1719-1724
    • Ross, D.M.1    Branford, S.2    Seymour, J.F.3
  • 12
    • 37249016890 scopus 로고    scopus 로고
    • BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria
    • Branford S, Seymour JF, Grigg A, et al. BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria. Clin Cancer Res 2007;13:7080-5.
    • (2007) Clin Cancer Res , vol.13 , pp. 7080-7085
    • Branford, S.1    Seymour, J.F.2    Grigg, A.3
  • 13
    • 84897007532 scopus 로고    scopus 로고
    • Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib
    • Hughes TP, Saglio G, Kantarjian HM, et al. Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib. Blood 2014;123:1353-60.
    • (2014) Blood , vol.123 , pp. 1353-1360
    • Hughes, T.P.1    Saglio, G.2    Kantarjian, H.M.3
  • 14
    • 84893136765 scopus 로고    scopus 로고
    • Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)
    • Jabbour E, Kantarjian HM, Saglio G, et al. Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION). Blood 2014;123:494-500.
    • (2014) Blood , vol.123 , pp. 494-500
    • Jabbour, E.1    Kantarjian, H.M.2    Saglio, G.3
  • 16
    • 84994813928 scopus 로고    scopus 로고
    • Unplanned discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia
    • Tsutsumi Y, Ito S, Ohigashi H, et al. Unplanned discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia. Mol Clin Oncol 2016;4:89-92.
    • (2016) Mol Clin Oncol , vol.4 , pp. 89-92
    • Tsutsumi, Y.1    Ito, S.2    Ohigashi, H.3
  • 17
    • 84906807375 scopus 로고    scopus 로고
    • Musculoskeletal pain in patients with chronic myeloid leukemia after discontinuation of imatinib: A tyrosine kinase inhibitor withdrawal syndrome?
    • Richter J, Söderlund S, Lübking A, et al. Musculoskeletal pain in patients with chronic myeloid leukemia after discontinuation of imatinib: a tyrosine kinase inhibitor withdrawal syndrome? J Clin Oncol 2014;32:2821-3.
    • (2014) J Clin Oncol , vol.32 , pp. 2821-2823
    • Richter, J.1    Söderlund, S.2    Lübking, A.3
  • 18
    • 84994838591 scopus 로고    scopus 로고
    • Musculoskeletal pain may be associated with imatinib withdrawal syndrome in chronic myeloid leukemia patients
    • [Epub ahead of print]
    • Ishii Y, Hagihara M, Kato A, et al. Musculoskeletal pain may be associated with imatinib withdrawal syndrome in chronic myeloid leukemia patients. Leuk Lymphoma 2015. [Epub ahead of print].
    • (2015) Leuk Lymphoma
    • Ishii, Y.1    Hagihara, M.2    Kato, A.3
  • 19
    • 84941317056 scopus 로고    scopus 로고
    • Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient-based survey on 1133 patients
    • Breccia M, Efficace F, Sica S, et al. Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient-based survey on 1133 patients. Leuk Res 2015;39:1055-9.
    • (2015) Leuk Res , vol.39 , pp. 1055-1059
    • Breccia, M.1    Efficace, F.2    Sica, S.3
  • 20
    • 81755166546 scopus 로고    scopus 로고
    • Natural killer cell mediated missing-self recognition can protect mice from primary chronic myeloid leukemia in vivo
    • Kijima M, Gardiol N, Held W. Natural killer cell mediated missing-self recognition can protect mice from primary chronic myeloid leukemia in vivo. PLoS One 2011;6:e27639.
    • (2011) PLoS One , vol.6
    • Kijima, M.1    Gardiol, N.2    Held, W.3
  • 21
    • 79961240453 scopus 로고    scopus 로고
    • Chronic myeloid leukemia patients in prolonged remission following interferon-α monotherapy have distinct cytokine and oligoclonal lymphocyte profile
    • Kreutzman A, Rohon P, Faber E, et al. Chronic myeloid leukemia patients in prolonged remission following interferon-α monotherapy have distinct cytokine and oligoclonal lymphocyte profile. PLoS One 2011;6:e23022.
    • (2011) PLoS One , vol.6
    • Kreutzman, A.1    Rohon, P.2    Faber, E.3
  • 22
    • 84883446131 scopus 로고    scopus 로고
    • Sustained upregulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib
    • Mizoguchi I, Yoshimoto T, Katagiri S, et al. Sustained upregulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib. Cancer Sci 2013;104:1146-53.
    • (2013) Cancer Sci , vol.104 , pp. 1146-1153
    • Mizoguchi, I.1    Yoshimoto, T.2    Katagiri, S.3
  • 23
    • 58149267985 scopus 로고    scopus 로고
    • Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
    • Kim DH, Kamel-Reid S, Chang H, et al. Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia. Haematologica 2009;94:135-9.
    • (2009) Haematologica , vol.94 , pp. 135-139
    • Kim, D.H.1    Kamel-Reid, S.2    Chang, H.3
  • 24
    • 68749108104 scopus 로고    scopus 로고
    • Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
    • Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 2009;23:1398-405.
    • (2009) Leukemia , vol.23 , pp. 1398-1405
    • Mustjoki, S.1    Ekblom, M.2    Arstila, T.P.3
  • 25
    • 84865776165 scopus 로고    scopus 로고
    • Second attempt to discontinue imatinib in CP-CML patients with a second sustained complete molecular response
    • Legros L, Rousselot P, Giraudier S, et al. Second attempt to discontinue imatinib in CP-CML patients with a second sustained complete molecular response. Blood 2012;120:1959-60.
    • (2012) Blood , vol.120 , pp. 1959-1960
    • Legros, L.1    Rousselot, P.2    Giraudier, S.3
  • 26
    • 84881298446 scopus 로고    scopus 로고
    • European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
    • Baccarani M, Deininger MW, Rosti G, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood 2013;122:872-84.
    • (2013) Blood , vol.122 , pp. 872-884
    • Baccarani, M.1    Deininger, M.W.2    Rosti, G.3
  • 27
    • 84977624843 scopus 로고    scopus 로고
    • Moving treatment-free remission into mainstream clinical practice in CML
    • Hughes TP, Ross DM. Moving treatment-free remission into mainstream clinical practice in CML. Blood 2016;128:17-23.
    • (2016) Blood , vol.128 , pp. 17-23
    • Hughes, T.P.1    Ross, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.