-
1
-
-
85016760715
-
International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human use
-
International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human use. Statistical principles for clinical trials E9. 1998.
-
(1998)
Statistical Principles for Clinical Trials E9
-
-
-
2
-
-
84961201800
-
Adaptive Designs undertaken in clinical research: A review of registered clinical trials
-
Hatfield I, Allison A, Flight L, et al. Adaptive Designs undertaken in clinical research: a review of registered clinical trials. Trials 2016;17:150.
-
(2016)
Trials
, vol.17
, pp. 150
-
-
Hatfield, I.1
Allison, A.2
Flight, L.3
-
3
-
-
33646245937
-
Adaptive designs in clinical drug development - An Executive Summary of the PhRMA Working Group
-
Gallo P, Chuang-Stein C, Dragalin V, et al. Adaptive designs in clinical drug development - an Executive Summary of the PhRMA Working Group. J Biopharm Stat 2006;16:275-83.
-
(2006)
J Biopharm Stat
, vol.16
, pp. 275-283
-
-
Gallo, P.1
Chuang-Stein, C.2
Dragalin, V.3
-
4
-
-
84903529904
-
Adaptive design: Results of 2012 survey on perception and use
-
Morgan CC, Huyck S, Jenkins M, et al. Adaptive design: results of 2012 survey on perception and use. Ther Innov Regul Sci 2014;48:473-81.
-
(2014)
Ther Innov Regul Sci
, vol.48
, pp. 473-481
-
-
Morgan, C.C.1
Huyck, S.2
Jenkins, M.3
-
5
-
-
44949171503
-
Adaptive design methods in clinical trials - a review
-
Chow SC, Chang M. Adaptive design methods in clinical trials - a review. Orphanet J Rare Dis 2008;3:11.
-
(2008)
Orphanet J Rare Dis
, vol.3
, pp. 11
-
-
Chow, S.C.1
Chang, M.2
-
8
-
-
78651230541
-
The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: A randomised controlled trial of point-of-care cardiac markers in the emergency department
-
Goodacre SW, Bradburn M, Cross E, The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart 2011;97:190-6.
-
(2011)
Heart
, vol.97
, pp. 190-196
-
-
Goodacre, S.W.1
Bradburn, M.2
Cross, E.3
-
9
-
-
84866729295
-
Influence of adaptive analysis on unnecessary patient recruitment: Reanalysis of the RATPAC trial
-
Sutton L, Julious S A, Goodacre SW. Influence of adaptive analysis on unnecessary patient recruitment: reanalysis of the RATPAC trial. Ann Emerg Med 2012;60:442-8.e1.
-
(2012)
Ann Emerg Med
, vol.60
, pp. 442-448.e1
-
-
Sutton, L.1
Julious, S.A.2
Goodacre, S.W.3
-
10
-
-
82255169270
-
Benefits, challenges and obstacles of adaptive clinical trial designs
-
Chow SC, Corey R. Benefits, challenges and obstacles of adaptive clinical trial designs. Orphanet J Rare Dis 2011;6:1.
-
(2011)
Orphanet J Rare Dis
, vol.6
, pp. 1
-
-
Chow, S.C.1
Corey, R.2
-
11
-
-
84954379510
-
Practical guide to sample size calculations: An introduction
-
Flight L, Julious SA. Practical guide to sample size calculations: an introduction. Pharm Stat 2016;15:68-74.
-
(2016)
Pharm Stat
, vol.15
, pp. 68-74
-
-
Flight, L.1
Julious, S.A.2
-
12
-
-
84863115528
-
Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: The PRIMO randomized controlled trial
-
Thadhani R, Appelbaum E, Pritchett Y, et al. Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial. JAMA 2012;307:674-84.
-
(2012)
JAMA
, vol.307
, pp. 674-684
-
-
Thadhani, R.1
Appelbaum, E.2
Pritchett, Y.3
-
13
-
-
79959252941
-
The use of group sequential, information-based sample size re-estimation in the design of the PRIMO study of chronic kidney disease
-
Pritchett Y, Jemiai Y, Chang Y, et al. The use of group sequential, information-based sample size re-estimation in the design of the PRIMO study of chronic kidney disease. Clin Trials 2011;8:165-74.
-
(2011)
Clin Trials
, vol.8
, pp. 165-174
-
-
Pritchett, Y.1
Jemiai, Y.2
Chang, Y.3
-
14
-
-
0025024025
-
Sequential clinical trials in emergency medicine
-
Lewis RJ, Bessen HA. Sequential clinical trials in emergency medicine. Ann Emerg Med 1990;19:1047-53.
-
(1990)
Ann Emerg Med
, vol.19
, pp. 1047-1053
-
-
Lewis, R.J.1
Bessen, H.A.2
-
16
-
-
84895537231
-
An investigation of the impact of futility analysis in publicly funded trials
-
Sully BG, Julious SA, Nicholl J. An investigation of the impact of futility analysis in publicly funded trials. Trials 2014;15:1.
-
(2014)
Trials
, vol.15
, pp. 1
-
-
Sully, B.G.1
Julious, S.A.2
Nicholl, J.3
-
17
-
-
56849102770
-
Subdissociative-dose ketamine versus fentanyl for analgesia during propofol procedural sedation: A randomized clinical trial
-
Messenger DW, Murray HE, Dungey PE, et al. Subdissociative-dose ketamine versus fentanyl for analgesia during propofol procedural sedation: a randomized clinical trial. Acad Emerg Med. 2008;15:877-86.
-
(2008)
Acad Emerg Med
, vol.15
, pp. 877-886
-
-
Messenger, D.W.1
Murray, H.E.2
Dungey, P.E.3
-
18
-
-
66249125341
-
A randomized, double-blind controlled study of jet lidocaine compared to jet placebo for pain relief in children undergoing needle insertion in the emergency department
-
Auerbach M, Tunik M, Mojica M. A randomized, double-blind controlled study of jet lidocaine compared to jet placebo for pain relief in children undergoing needle insertion in the emergency department. Acad Emerg Med 2009;16:388-93.
-
(2009)
Acad Emerg Med
, vol.16
, pp. 388-393
-
-
Auerbach, M.1
Tunik, M.2
Mojica, M.3
-
19
-
-
84942308496
-
Missing steps in a staircase: A qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials
-
Dimairo M, Boote J, Julious SA, et al. Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials. Trials 2015;16:1.
-
(2015)
Trials
, vol.16
, pp. 1
-
-
Dimairo, M.1
Boote, J.2
Julious, S.A.3
-
21
-
-
33646257465
-
Application of adaptive designs - A review
-
Bauer P, Einfalt J. Application of adaptive designs - a review. Biometrical J 200648:493-506.
-
(2006)
Biometrical J
, vol.48
, pp. 493-506
-
-
Bauer, P.1
Einfalt, J.2
|