Gasdermin C is upregulated by inactivation of transforming growth factor β receptor type II in the presence of mutated Apc, promoting colorectal cancer proliferation

PLoS ONE

Volumn 11, Issue 11, 2016, Pages

  Miguchi, Masashi ^a   Hinoi, Takao ^a,b   Shimomura, Manabu ^a   Adachi, Tomohiro ^a   Saito, Yasufumi ^a   Niitsu, Hiroaki ^a   Kochi, Masatoshi ^a   Sada, Haruki ^a   Sotomaru, Yusuke ^a   Ikenoue, Tsuneo ^c   Shigeyasu, Kunitoshi ^d   Tanakaya, Kohji ^d   Kitadai, Yasuhiko ^a,e   Sentani, Kazuhiro ^a   Oue, Naohide ^a   Yasui, Wataru ^a   Ohdan, Hideki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d IWAKUNI NATIONAL HOSPITAL   (Japan)

^e PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; GASDERMIN C; REGULATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; ADENOMATOUS POLYPOSIS COLI PROTEIN, MOUSE; DNA BINDING PROTEIN; GSDMC PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR CDX2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PROTEIN DETERMINATION; PROTEIN FUNCTION; TRANSFORMING GROWTH FACTOR BETA2 GENE; TUMOR XENOGRAFT; UPREGULATION; ADENOCARCINOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; COLON; COLORECTAL TUMOR; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MUTATION; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE;

ADENOCARCINOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BIOMARKERS, TUMOR; CDX2 TRANSCRIPTION FACTOR; CELL LINE, TUMOR; CELL PROLIFERATION; COLON; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROARRAY ANALYSIS; MUTATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84994754097     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0166422     Document Type: Article

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