Cumulative burden of cardiovascular morbidity in paediatric, adolescent, and young adult survivors of Hodgkin's lymphoma: an analysis from the St Jude Lifetime Cohort Study

The Lancet Oncology

Volumn 17, Issue 9, 2016, Pages 1325-1334

  Bhakta, Nickhill ^a   Liu, Qi ^b   Yeo, Frederick ^a   Baassiri, Malek ^a   Ehrhardt, Matthew J ^a   Srivastava, Deo K ^a   Metzger, Monika L ^a   Krasin, Matthew J ^a   Ness, Kirsten K ^a   Hudson, Melissa M ^a   Yasui, Yutaka ^a,b   Robison, Leslie L ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE;

ADOLESCENT; ADULT; AORTA ANEURYSM; ARTERIOVENOUS MALFORMATION; ARTICLE; ATRIOVENTRICULAR BLOCK; BLOOD VESSEL OCCLUSION; CANCER RADIOTHERAPY; CANCER SURVIVOR; CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; COR PULMONALE; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EXPOSURE; ESSENTIAL HYPERTENSION; FEMALE; HEART ARRHYTHMIA; HEART ATRIUM MYXOMA; HEART INFARCTION; HEART MUSCLE CONDUCTION DISTURBANCE; HEART RIGHT VENTRICULAR SYSTOLIC DYSFUNCTION; HODGKIN DISEASE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE DISEASE; PERICARDITIS; PRIORITY JOURNAL; PULMONARY HYPERTENSION; QT PROLONGATION; RADIATION DOSE; RADIATION EXPOSURE; RAYNAUD PHENOMENON; RETROSPECTIVE STUDY; SINUS BRADYCARDIA; SINUS TACHYCARDIA; SURVIVAL TIME; SYSTOLIC DYSFUNCTION; THROMBUS; YOUNG ADULT; ADVERSE EFFECTS; CANCER STAGING; CARDIOVASCULAR DISEASES; CASE CONTROL STUDY; COMPARATIVE STUDY; COMPLICATION; FOLLOW UP; LONGITUDINAL STUDY; MIDDLE AGED; MORBIDITY; MULTIMODALITY CANCER THERAPY; PRESCHOOL CHILD; PROGNOSIS; PROSPECTIVE STUDY; RISK FACTOR; STATISTICS AND NUMERICAL DATA; SURVIVAL RATE; SURVIVOR; UNITED STATES;

ADOLESCENT; ADULT; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; HODGKIN DISEASE; HUMANS; INCIDENCE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MORBIDITY; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; SURVIVORS; UNITED STATES; YOUNG ADULT;

EID: 84994517579     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(16)30215-7     Document Type: Article

References (32)

1. 1 US Department of Health and Human Services; National Cancer Institute. Cancer incidence and survival among children and adolescents: United States SEER Program 1975–1995. 2013. Bethesda, MD, USA: 1–192.
2. 2 Phillips, SM, Padgett, LS, Leisenring, WM, et al. Survivors of childhood cancer in the United States: prevalence and burden of morbidity. Cancer Epidemiol Biomarkers Prev 24 (2015), 653–663.
3. 3 Adams, MJ, Lipsitz, SR, Colan, SD, et al. Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy. J Clin Oncol 22 (2004), 3139–3148.
4. 4 Castellino, SM, Geiger, AM, Mertens, AC, et al. Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. Blood 117 (2011), 1806–1816.
5. 5 Galper, SL, Yu, JB, Mauch, PM, et al. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation. Blood 117 (2011), 412–418.
6. 6 Myrehaug, S, Pintilie, M, Tsang, R, et al. Cardiac morbidity following modern treatment for Hodgkin lymphoma: supra-additive cardiotoxicity of doxorubicin and radiation therapy. Leuk Lymphoma 49 (2008), 1486–1493.
7. 7 Yeh, JM, Nekhlyudov, L, Goldie, SJ, Mertens, AC, Diller, L, A model-based estimate of cumulative excess mortality in survivors of childhood cancer. Ann Intern Med 152 (2010), 409–417 W131–38.
8. 8 Mulrooney, DA, Yeazel, MW, Kawashima, T, et al. Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ, 339, 2009, b4606.
9. 9 Constine, LS, Schwartz, RG, Savage, DE, King, V, Muhs, A, Cardiac function, perfusion, and morbidity in irradiated long-term survivors of Hodgkin's disease. Radiat Oncol Biol 39 (1997), 897–906.
10. 10 Chen, MH, Blackington, LH, Zhou, J, et al. Blood pressure is associated with occult cardiovascular disease in prospectively studied Hodgkin lymphoma survivors after chest radiation. Leuk Lymphoma 55 (2014), 2477–2483.
11. 11 Cutter, DJ, Schaapveld, M, Darby, SC, et al. Risk of valvular heart disease after treatment for Hodgkin lymphoma. J Natl Cancer Inst, 2015, 107, 10.1093/jnci/djv008.
12. 12 Hull, MC, Morris, CG, Pepine, CJ, Mendenhall, NP, Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of Hodgkin lymphoma treated with radiation therapy. JAMA 290 (2003), 2831–2837.
13. 13 Franco, VI, Lipshultz, SE, Cardiac complications in childhood cancer survivors treated with anthracyclines. Cardiol Young 25:suppl 2 (2015), 107–116.
14. 14 van Nimwegen, FA, Schaapveld, M, Cutter, DJ, et al. Radiation dose–response relationship for risk of coronary heart disease in survivors of Hodgkin lymphoma. J Clin Oncol 34 (2016), 235–243.
15. 15 Schellong, G, Riepenhausen, M, Bruch, C, et al. Late valvular and other cardiac diseases after different doses of mediastinal radiotherapy for Hodgkin disease in children and adolescents: report from the longitudinal GPOH follow-up project of the German-Austrian DAL-HD studies. Pediatr Blood Cancer 55 (2010), 1145–1152.
16. 16 Yeh, JM, Diller, L, Pediatric Hodgkin lymphoma: trade-offs between short- and long-term mortality risks. Blood 120 (2012), 2195–2202.
17. 17 Chow, EJ, Chen, Y, Kremer, LC, et al. Individual prediction of heart failure among childhood cancer survivors. J Clin Oncol 33 (2015), 394–402.
18. 18 Hudson, MM, Mulrooney, DA, Bowers, DC, et al. High-risk populations identified in Childhood Cancer Survivor Study investigations: implications for risk-based surveillance. J Clin Oncol 27 (2009), 2405–2414.
19. 19 Oeffinger, KC, Mertens, AC, Sklar, CA, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med 355 (2006), 1572–1582.
20. 20 Hudson, MM, Ness, KK, Gurney, JG, et al. Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA 309 (2013), 2371–2381.
21. 21 Hudson, MM, Ness, KK, Nolan, VG, et al. Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study. Pediatr Blood Cancer 56 (2011), 825–836.
22. 22 Aleman, BMP, van den Belt-Dusebout, AW, Klokman, WJ, Van't Veer, MB, Bartelink, H, van Leeuwen, FE, Long-term cause-specific mortality of patients treated for Hodgkin's disease. J Clin Oncol 21 (2003), 3431–3439.
23. 23 Stovall, M, Weathers, R, Kasper, C, et al. Dose reconstruction for therapeutic and diagnostic radiation exposures: use in epidemiological studies. Radiat Res 166 (2006), 141–157.
24. 24 Armenian, SH, Hudson, MM, Mulder, RL, et al. Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group. Lancet Oncol 16 (2015), e123–e136.
25. 25 Services UDOHAH. National Cancer Institute: Common Terminology Criteria for Adverse Events (CTCAE) v 4.03 (internet). http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_8.5x11.pdf, 2009 (accessed May 16, 2016).
26. 26 Geskus, RB, Cause-specific cumulative incidence estimation and the fine and gray model under both left truncation and right censoring. Biometrics 67 (2011), 39–49.
27. 27 Molenberghs, G, Fitzmaurice, G, Kenward, MG, Tsiatis, A, Verbeke, G, Handbook of missing data methodology, 2014, CRC Press, Boca Raton, FL.
28. 28 Dong, H, Robison, LL, Leisenring, WM, Martin, LJ, Armstrong, GT, Yasui, Y, Estimating the burden of recurrent events in the presence of competing risks: the method of mean cumulative count. Am J Epidemiol 181 (2015), 532–540.
29. 29 Berridge, DM, An application of a marked point process in pre-clinical medicine. Stat Med 15 (1996), 2751–2762.
30. 30 Ness, KK, Krull, KR, Jones, KE, et al. Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study. J Clin Oncol 31 (2013), 4496–4503.
31. 31 Landier, W, Bhatia, S, Eshelman, DA, et al. Development of risk-based guidelines for pediatric cancer survivors: the Children's Oncology Group Long-Term Follow-Up Guidelines from the Children's Oncology Group Late Effects Committee and Nursing Discipline. J Clin Oncol 22 (2004), 4979–4990.
32. 32 Küpeli, S, Hazirolan, T, Varan, A, et al. Evaluation of coronary artery disease by computed tomography angiography in patients treated for childhood Hodgkin's lymphoma. J Clin Oncol 28 (2010), 1025–1030.