Randomized Pilot Trial of a Telephone Symptom Management Intervention for Symptomatic Lung Cancer Patients and Their Family Caregivers

Journal of Pain and Symptom Management

Volumn 52, Issue 4, 2016, Pages 469-482

  Mosher, Catherine E ^a   Winger, Joseph G ^a   Hanna, Nasser ^b   Jalal, Shadia I ^b,c   Einhorn, Lawrence H ^b   Birdas, Thomas J ^b   Ceppa, DuyKhanh P ^b   Kesler, Kenneth A ^b   Schmitt, Jordan ^b,c   Kashy, Deborah A ^d   Champion, Victoria L ^e  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

^e INDIANA UNIVERSITY SCHOOL OF NURSING   (United States)

Author keywords

cognitive behavioral; distress; family caregivers; Lung cancer; psychosocial interventions; symptom management

Indexed keywords

ADULT; AGED; ANXIETY DISORDER; ARTICLE; CANCER PATIENT; CANCER STAGING; CAREGIVER; CAREGIVER BURDEN; COGNITIVE BEHAVIORAL THERAPY; CONTROLLED STUDY; COPING BEHAVIOR; DEPRESSION; DISEASE SEVERITY; DISTRESS SYNDROME; DYSPNEA; EDUCATION; EMOTION; EMPLOYMENT STATUS; FATIGUE; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; PAIN; PAIN SEVERITY; PATIENT EDUCATION; PSYCHOSOCIAL CARE; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SELF CONCEPT; SMALL CELL LUNG CANCER; TELEMEDICINE; TELEPHONE; TREATMENT OUTCOME; COGNITIVE THERAPY; DISEASE MANAGEMENT; LUNG TUMOR; MIDDLE AGED; PILOT STUDY; PSYCHOLOGY; SELF REPORT; TREATMENT FAILURE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CAREGIVERS; COGNITIVE THERAPY; DISEASE MANAGEMENT; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PATIENT EDUCATION AS TOPIC; PILOT PROJECTS; SELF EFFICACY; SELF REPORT; TELEMEDICINE; TREATMENT FAILURE;

EID: 84994507687     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2016.04.006     Document Type: Article

References (79)

1. 1 American Cancer Society. Cancer facts and figures 2015. 2015, American Cancer Society, Atlanta, GA.
2. 2 Hopwood, P., Stephens, R.J., Symptoms at presentation for treatment in patients with lung cancer: implications for the evaluation of palliative treatment. The Medical Research Council (MRC) Lung Cancer Working Party. Br J Cancer 71 (1995), 633–636.
3. 3 Kurtz, M.E., Kurtz, J.C., Stommel, M., Given, C.W., Given, B., Predictors of depressive symptomatology of geriatric patients with lung cancer-a longitudinal analysis. Psychooncology 11 (2002), 12–22.
4. 4 Rolke, H.B., Bakke, P.S., Gallefoss, F., Health related quality of life, mood disorders and coping abilities in an unselected sample of patients with primary lung cancer. Respir Med 102 (2008), 1460–1467.
5. 5 Dudgeon, D.J., Kristjanson, L., Sloan, J.A., Lertzman, M., Clement, K., Dyspnea in cancer patients: prevalence and associated factors. J Pain Symptom Manage 21 (2001), 95–102.
6. 6 Zabora, J., BrintzenhofeSzoc, K., Curbow, B., Hooker, C., Piantadosi, S., The prevalence of psychological distress by cancer site. Psychooncology 10 (2001), 19–28.
7. 7 Linden, W., Vodermaier, A., Mackenzie, R., Greig, D., Anxiety and depression after cancer diagnosis: prevalence rates by cancer type, gender, and age. J Affect Disord 141 (2012), 343–351.
8. 8 Cooley, M.E., Short, T.H., Moriarty, H.J., Symptom prevalence, distress, and change over time in adults receiving treatment for lung cancer. Psychooncology 12 (2003), 694–708.
9. 9 Hopwood, P., Stephens, R.J., Depression in patients with lung cancer: prevalence and risk factors derived from quality-of-life data. J Clin Oncol 18 (2000), 893–903.
10. 10 Shin, J.A., Kosiba, J.D., Traeger, L., et al. Dyspnea and panic among patients with newly diagnosed non-small cell lung cancer. J Pain Symptom Manage 48 (2014), 465–470.
11. 11 Iyer, S., Roughley, A., Rider, A., Taylor-Stokes, G., The symptom burden of non-small cell lung cancer in the USA: a real-world cross-sectional study. Support Care Cancer 22 (2014), 181–187.
12. 12 Porter, L.S., Keefe, F.J., Garst, J., McBride, C.M., Baucom, D., Self-efficacy for managing pain, symptoms, and function in patients with lung cancer and their informal caregivers: associations with symptoms and distress. Pain 137 (2008), 306–315.
13. 13 Chambers, S.K., Baade, P., Youl, P., et al. Psychological distress and quality of life in lung cancer: the role of health-related stigma, illness appraisals and social constraints. Psychooncology 24 (2015), 1569–1577.
14. 14 Carmack Taylor, C.L., Badr, H., Lee, J.H., et al. Lung cancer patients and their spouses: psychological and relationship functioning within 1 month of treatment initiation. Ann Behav Med 36 (2008), 129–140.
15. 15 Persson, C., Östlund, U., Wennman-Larsen, A., Wengström, Y., Gustavsson, P., Health-related quality of life in significant others of patients dying from lung cancer. Palliat Med 22 (2008), 239–247.
16. 16 Ellis, J., The impact of lung cancer on patients and carers. Chron Respir Dis 9 (2012), 39–47.
17. 17 Fujinami, R., Sun, V., Zachariah, F., et al. Family caregivers' distress levels related to quality of life, burden, and preparedness. Psychooncology 24 (2015), 54–62.
18. 18 Grant, M., Sun, V., Fujinami, R., et al. Family caregiver burden, skills preparedness, and quality of life in non-small cell lung cancer. Oncol Nurs Forum 40 (2013), 337–346.
19. 19 Kim, Y., Duberstein, P.R., Sörensen, S., Larson, M.R., Levels of depressive symptoms in spouses of people with lung cancer: effects of personality, social support, and caregiving burden. Psychosomatics 46 (2005), 123–130.
20. 20 Ӧstlund, U., Wennman-Larsen, A., Persson, C., Gustavsson, P., Wengström, Y., Mental health in significant others of patients dying from lung cancer. Psychooncology 19 (2010), 29–37.
21. 21 Haun, M.W., Sklenarova, H., Brechtel, A., Herzog, W., Hartmann, M., Distress in cancer patients and their caregivers and association with the caregivers' perception of dyadic communication. Oncol Res Treat 37 (2014), 384–388.
22. 22 Mosher, C.E., Champion, V.L., Hanna, N., et al. Support service use and interest in support services among distressed family caregivers of lung cancer patients. Psychooncology 22 (2013), 1549–1556.
23. 23 Braun, M., Mikulincer, M., Rydall, A., Walsh, A., Rodin, G., Hidden morbidity in cancer: spouse caregivers. J Clin Oncol 25 (2007), 4829–4834.
24. 24 Bakas, T., Lewis, R.R., Parsons, J.E., Caregiving tasks among family caregivers of patients with lung cancer. Oncol Nurs Forum 28 (2001), 847–854.
25. 25 Mosher, C.E., Jaynes, H.A., Hanna, N., Ostroff, J.S., Distressed family caregivers of lung cancer patients: an examination of psychosocial and practical challenges. Support Care Cancer 21 (2013), 431–437.
26. 26 Temel, J.S., Greer, J.A., Muzikansky, A., et al. Early palliative care for patients with metastatic non–small-cell lung cancer. N Engl J Med 363 (2010), 733–742.
27. 27 Smith, T.J., Temin, S., Alesi, E.R., et al. American Society of Clinical Oncology provisional clinical opinion: the integration of palliative care into standard oncology care. J Clin Oncol 30 (2012), 880–887.
28. 28 Ford, D.W., Koch, K.A., Ray, D.E., Selecky, P.A., Palliative and end-of-life care in lung cancer: diagnosis and management of lung cancer, 3rd ed.: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143 (2013), e498S–e512.
29. 29 Sanders, S.L., Bantum, E.O., Owen, J.E., Thornton, A.A., Stanton, A.L., Supportive care needs in patients with lung cancer. Psychooncology 19 (2010), 480–489.
30. 30 Osse, B.H., Vernooij-Dassen, M.J., Schadé, E., Grol, R.P., Problems experienced by the informal caregivers of cancer patients and their needs for support. Cancer Nurs 29 (2006), 378–388.
31. 31 Northouse, L.L., Williams, A.L., Given, B., McCorkle, R., Psychosocial care for family caregivers of patients with cancer. J Clin Oncol 30 (2012), 1227–1234.
32. 32 Northouse, L.L., Katapodi, M.C., Song, L., Zhang, L., Mood, D.W., Interventions with family caregivers of cancer patients: meta-analysis of randomized trials. CA Cancer J Clin 60 (2010), 317–339.
33. 33 Rueda, J.R., Solà, I., Pascual, A., Subirana Casacuberta, M., Non-invasive interventions for improving well-being and quality of life in patients with lung cancer. Cochrane Database Syst Rev, 9, 2011, CD004282.
34. 34 Badr, H., Krebs, P., A systematic review and meta-analysis of psychosocial interventions for couples coping with cancer. Psychooncology 22 (2013), 1688–1704.
35. 35 Dixon, K.E., Keefe, F.J., Scipio, C.D., Perri, L.M., Abernethy, A.P., Psychological interventions for arthritis pain management in adults: a meta-analysis. Health Psychol 26 (2007), 241–250.
36. 36 Malouff, J.M., Thorsteinsson, E.B., Rooke, S.E., Bhullar, N., Schutte, N.S., Efficacy of cognitive behavioral therapy for chronic fatigue syndrome: a meta-analysis. Clin Psychol Rev 28 (2008), 736–745.
37. 37 Tatrow, K., Montgomery, G.H., Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis. J Behav Med 29 (2006), 17–27.
38. 38 Redd, W.H., Montgomery, G.H., DuHamel, K.N., Behavioral intervention for cancer treatment side effects. J Natl Cancer Inst 93 (2001), 810–823.
39. 39 Kangas, M., Bovbjerg, D.H., Montgomery, G.H., Cancer-related fatigue: a systematic and meta-analytic review of non-pharmacological therapies for cancer patients. Psychol Bull 134 (2008), 700–741.
40. 40 Morley, S., Eccleston, C., Williams, A., Systematic review and meta-analysis of randomized controlled trials of cognitive behaviour therapy and behaviour therapy for chronic pain in adults, excluding headache. Pain 80 (1999), 1–13.
41. 41 Luebbert, K., Dahme, B., Hasenbring, M., The effectiveness of relaxation training in reducing treatment-related symptoms and improving emotional adjustment in acute non-surgical cancer treatment: a meta-analytical review. Psychooncology 10 (2001), 490–502.
42. 42 McLean, L.M., Walton, T., Rodin, G., Esplen, M.J., Jones, J.M., A couple-based intervention for patients and caregivers facing end-stage cancer: outcomes of a randomized controlled trial. Psychooncology 22 (2013), 28–38.
43. 43 Porter, L.S., Keefe, F.J., Baucom, D.H., et al. Partner-assisted emotional disclosure for patients with gastrointestinal cancer: results from a randomized controlled trial. Cancer 115 (2009), 4326–4338.
44. 44 Badr, H., Smith, C.B., Goldstein, N.E., Gomez, J.E., Redd, W.H., Dyadic psychosocial intervention for advanced lung cancer patients and their family caregivers: results of a randomized pilot trial. Cancer 121 (2015), 150–158.
45. 45 Porter, L.S., Keefe, F.J., Garst, J., et al. Caregiver-assisted coping skills training for lung cancer: results of a randomized clinical trial. J Pain Symptom Manage 41 (2011), 1–13.
46. 46 Given, C., Given, B., Rahbar, M., et al. Effect of a cognitive behavioral intervention on reducing symptom severity during chemotherapy. J Clin Oncol 22 (2004), 507–516.
47. 47 Given, B., Given, C.W., Sikorskii, A., et al. The impact of providing symptom management assistance on caregiver reaction: results of a randomized trial. J Pain Symptom Manage 32 (2006), 433–443.
48. 48 Kurtz, M.E., Kurtz, J.C., Given, C.W., Given, B., A randomized, controlled trial of a patient/caregiver symptom control intervention: effects on depressive symptomatology of caregivers of cancer patients. J Pain Symptom Manage 30 (2005), 112–122.
49. 49 O'Hara, R.E., Hull, J.G., Lyons, K.D., et al. Impact on caregiver burden of a patient-focused palliative care intervention for patients with advanced cancer. Palliat Support Care 8 (2010), 395–404.
50. 50 Greer, J.A., Park, E.R., Prigerson, H.G., Safren, S.A., Tailoring cognitive-behavioral therapy to treat anxiety comorbid with advanced cancer. J Cogn Psychother 24 (2010), 294–313.
51. 51 Moorey, S., Greer, S., Cognitive-behavioral therapy for people with cancer. 2002, Oxford University Press, New York.
52. 52 Keefe, F.J., Abernethy, A.P., Campbell, L.C., Psychological approaches to understanding and treating disease-related pain. Annu Rev Psychol 56 (2005), 601–630.
53. 53 Barlow, J., Wright, C., Sheasby, J., Turner, A., Hainsworth, J., Self-management approaches for people with chronic conditions: a review. Patient Educ Couns 48 (2002), 177–187.
54. 54 Bandura, A., Social learning theory. 1977, Prentice-Hall, Englewood Cliffs, NJ.
55. 55 Bandura, A., Health promotion by social cognitive means. Health Educ Behav 31 (2004), 143–164.
56. 56 Kroenke, K., Spitzer, R.L., Williams, J.B., The Patient Health Questionnaire-2: validity of a two-item depression screener. Med Care 41 (2003), 1284–1292.
57. 57 Kroenke, K., Spitzer, R.L., Williams, J.B., Monahan, P.O., Lowe, B., Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med 146 (2007), 317–325.
58. 58 Krebs, E.E., Lorenz, K.A., Bair, M.J., et al. Development and initial validation of the PEG, a three-item scale assessing pain intensity and interference. J Gen Intern Med 24 (2009), 733–738.
59. 59 McHorney, C.A., Ware, J.E. Jr., Raczek, A.E., The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care 31 (1993), 247–263.
60. 60 O'Connor, P.J., Evaluation of four highly cited energy and fatigue mood measures. J Psychosom Res 57 (2004), 435–441.
61. 61 Portenoy, R.K., Thaler, H.T., Kornblith, A.B., et al. The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. Eur J Cancer 30A (1994), 1326–1336.
62. 62 Callahan, C.M., Unverzagt, F.W., Hui, S.L., Perkins, A.J., Hendrie, H.C., Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care 40 (2002), 771–781.
63. 63 Kraemer, H.C., Thiemann, S., How many subjects? Statistical power analysis in research. 1987, Sage Publications, Thousand Oaks, CA.
64. 64 Bauer, J., Capra, S., Ferguson, M., Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr, 56, 2002, 779.
65. 65 Dajczman, E., Kasymjanova, G., Kreisman, H., et al. Should patient-rated performance status affect treatment decisions in advanced lung cancer?. J Thorac Oncol 3 (2008), 1133–1136.
66. 66 Kroenke, K., Spitzer, R.L.M.D., The PHQ-9: a new depression diagnostic and severity measure. Psychiatr Ann 32 (2002), 509–515.
67. 67 Kroenke, K., Strine, T.W., Spitzer, R.L., et al. The PHQ-8 as a measure of current depression in the general population. J Affect Disord 114 (2009), 163–173.
68. 68 Cleeland, C.S., Gonin, R., Hatfield, A.K., et al. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med 330 (1994), 592–596.
69. 69 Kroenke, K., Theobald, D., Norton, K., et al. The Indiana Cancer Pain and Depression (INCPAD) trial: design of a telecare management intervention for cancer-related symptoms and baseline characteristics of study participants. Gen Hosp Psychiatry 31 (2009), 240–253.
70. 70 Donovan, K.A., Jacobsen, P.B., Small, B.J., Munster, P.N., Andrykowski, M.A., Identifying clinically meaningful fatigue with the Fatigue Symptom Inventory. J Pain Symptom Manage 36 (2008), 480–487.
71. 71 Hann, D.M., Denniston, M.M., Baker, F., Measurement of fatigue in cancer patients: further validation of the Fatigue Symptom Inventory. Qual Life Res 9 (2000), 847–854.
72. 72 Anderson, K.O., Dowds, B.N., Pelletz, R.E., Edwards, W.T., Peeters-Asdourian, C., Development and initial validation of a scale to measure self-efficacy beliefs in patients with chronic pain. Pain 63 (1995), 77–84.
73. 73 Kilbourn, K.M., Costenaro, A., Madore, S., et al. Feasibility of a telephone-based counseling program for informal caregivers of hospice patients. J Palliat Med 14 (2011), 1200–1205.
74. 74 Lepore, S.J., Silver, R.C., Wortman, C.B., Wayment, H.A., Social constraints, intrusive thoughts, and depressive symptoms among bereaved mothers. J Pers Soc Psychol 70 (1996), 271–282.
75. 75 Given, C.W., Given, B., Stommel, M., et al. The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. Res Nurs Health 15 (1992), 271–283.
76. 76 Kenny, D., Kashy, D., Cook, W., Dyadic data analysis. 2006, Guilford Press, New York.
77. 77 Atkins, D.C., Using multilevel models to analyze couple and family treatment data: basic and advanced issues. J Fam Psychol 19 (2005), 98–110.
78. 78 Hastert, T.A., Beresford, S.A., Sheppard, L., White, E., Disparities in cancer incidence and mortality by area-level socioeconomic status: a multilevel analysis. J Epidemiol Community Health 69 (2015), 168–176.
79. 79 Northouse, L.L., Mood, D.W., Schafenacker, A., et al. Randomized clinical trial of a brief and extensive dyadic intervention for advanced cancer patients and their family caregivers. Psychooncology 22 (2013), 555–563.