Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients

Disease Markers

Volumn 2016, Issue , 2016, Pages

  Luedde, Mark ^a   Benz, Fabian ^b   Niedeggen, Jennifer ^b   Vucur, Mihael ^b   Hippe, Hans Joerg ^a   Spehlmann, Martina E ^a   Schueller, Florian ^a   Loosen, Sven ^a   Frey, Norbert ^a   Trautwein, Christian ^b   Koch, Alexander ^b   Luedde, Tom ^b   Tacke, Frank ^b   Roderburg, Christoph ^b  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; BIOLOGICAL MARKER; CYTOKINE; LEPTIN RECEPTOR; OMENTIN; UNCLASSIFIED DRUG; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; ITLN1 PROTEIN, HUMAN; LECTIN;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; INFLAMMATORY DISEASE; INTENSIVE CARE UNIT; LONG TERM SURVIVAL; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; OVERALL SURVIVAL; PREDICTIVE VALUE; PROGNOSIS; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SEPSIS; SERUM; SHORT TERM SURVIVAL; ADOLESCENT; BLOOD; CASE CONTROL STUDY; MIDDLE AGED; PATHOLOGY; SURVIVAL ANALYSIS; VERY ELDERLY;

ADIPONECTIN; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS; CASE-CONTROL STUDIES; CRITICAL ILLNESS; CYTOKINES; FEMALE; GPI-LINKED PROTEINS; HUMANS; LECTINS; MALE; MIDDLE AGED; RECEPTORS, LEPTIN; SEPSIS; SURVIVAL ANALYSIS;

EID: 84994460442     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.1155/2016/3149243     Document Type: Article

References (45)

1. I. Ilias, D. A. Vassiliadi, M. Theodorakopoulou et al., "Adipose tissue lipolysis and circulating lipids in acute and subacute critical illness: Effects of shock and treatment, " Journal of Critical Care, vol. 29, no. 6, pp. 1130. e5-1130. e9, 2014.
2. C. Acharya, S. Navina, and V. P. Singh, "Role of pancreatic fat in the outcomes of pancreatitis, " Pancreatology, vol. 14, no. 5, pp. 403-408, 2014.
3. S. J. Van Cromphaut, I. Vanhorebeek, and G. Van den Berghe, "Glucose metabolism and insulin resistance in sepsis, " Current Pharmaceutical Design, vol. 14, no. 19, pp. 1887-1899, 2008.
4. A. Koch, R. Weiskirchen, H. W. Zimmermann, E. Sanson, C. Trautwein, and F. Tacke, "Relevance of serum leptin and leptinreceptor concentrations in critically ill patients, " Mediators of Inflammation, vol. 2010, Article ID 473540, 9 pages, 2010.
5. B. K. Tan, R. Adya, and H. S. Randeva, "Omentin: A novel link between inflammation, diabesity, and cardiovascular disease, " Trends in Cardiovascular Medicine, vol. 20, no. 5, pp. 143-148, 2010.
6. K. Kazama, T. Usui, M. Okada, Y. Hara, and H. Yamawaki, "Omentin plays an anti-inflammatory role through inhibition of TNF-induced superoxide production in vascular smooth muscle cells, " European Journal of Pharmacology, vol. 686, no. 1-3, pp. 116-123, 2012.
7. C. M. De Souza Batista, R.-Z. Yang, M.-J. Lee et al., "Omentin plasma levels and gene expression are decreased in obesity, " Diabetes, vol. 56, no. 6, pp. 1655-1661, 2007.
8. M. Lapointe, P. Poirier, J. Martin, M. Bastien, A. Auclair, and K. Cianflone, "Omentin changes following bariatric surgery and predictive links with biomarkers for risk of cardiovascular disease, " Cardiovascular Diabetology, vol. 13, no. 1, article 124, 2014.
9. K. Ohashi, R. Shibata, T. Murohara, andN. Ouchi, "Role of antiinflammatory adipokines in obesity-related diseases, " Trends in Endocrinology andMetabolism, vol. 25, no. 7, pp. 348-355, 2014.
10. E. Carmina, "Obesity, adipokines and metabolic syndrome in polycystic ovary syndrome, " Frontiers ofHormone Research, vol. 40, pp. 40-50, 2013.
11. C. Herder, M. Carstensen, and D. M. Ouwens, "Antiinflammatory cytokines and risk of type 2 diabetes, " Diabetes, Obesity and Metabolism, vol. 15, no. 3, pp. 39-50, 2013.
12. J. Yin, P. Hou, Z. Wu, and Y. Nie, "Decreased levels of serum omentin-1 in patients with inflammatory bowel disease, " Medical Science Monitor, vol. 21, pp. 118-122, 2015.
13. C. Roderburg, F. Benz, D. V. Cardenas et al., "Persistently elevated osteopontin serum levels predictmortality in critically ill patients, " Critical Care, vol. 19, article 271, 2015.
14. M. Singer, C. S. Deutschman, C. W. Seymour et al., "The third international consensus definitions for sepsis and septic shock (Sepsis-3), "The Journal of theAmericanMedical Association, vol. 315, no. 8, pp. 801-810, 2016.
15. F. Tacke, C. Roderburg, F. Benz et al., "Levels of circulating mir-133a are elevated in sepsis and predict mortality in critically ill patients, " Critical Care Medicine, vol. 42, no. 5, pp. 1096-1104, 2014.
16. F. Benz, F. Tacke, M. Luedde et al., "Circulating microRNA-223 serum levels do not predict sepsis or survival in patients with critical illness, " Disease Markers, vol. 2015 article 384208, 10 pages, 2015.
17. A. Koch, E. Sanson, A. Helm, S. Voigt, C. Trautwein, and F. Tacke, "Regulation and prognostic relevance of serum ghrelin concentrations in critical illness and sepsis, " Critical Care, vol. 14, no. 3, article R94, 2010.
18. A. Koch, O. A. Gressner, E. Sanson, F. Tacke, andC. Trautwein, "Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients, " Critical Care, vol. 13, no. 3, article R95, 2009.
19. F. Benz, C. Roderburg, D. Vargas Cardenas et al., "U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis, " Experimental&MolecularMedicine, vol. 45, article e42, 2013.
20. C. Roderburg, F. Benz, D. VargasCardenas et al., "Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases, " Liver International, vol. 35, no. 4, pp. 1172-1184, 2015.
21. S. E. Siegelaar, M. Hickmann, J. B. L. Hoekstra, F. Holleman, and J. H. DeVries, "The effect of diabetes onmortality in critically ill patients: A systematic review and meta-analysis, " Critical Care, vol. 15, article R205, 2011.
22. M. K. Badman and J. S. Flier, "The adipocyte as an active participant in energy balance andmetabolism, " Gastroenterology, vol. 132, no. 6, pp. 2103-2115, 2007.
23. R. Thoonen, A. G. Hindle, and M. Scherrer-Crosbie, "Brown adipose tissue: The heat is on the heart, " American Journal of Physiology-Heart and Circulatory Physiology, vol. 310, no. 11, pp. H1592-H1605, 2016.
24. E. Neumann, S. Junker, G. Schett, K. Frommer, and U. Müller-Ladner, "Adipokines in bone disease, " Nature Reviews Rheumatology, vol. 12, no. 5, pp. 296-302, 2016.
25. C. H. Lee, Y. C. Woo, Y. Wang, C. Y. Yeung, A. Xu, and K. S. L. Lam, "Obesity, adipokines and cancer: An update, " Clinical Endocrinology, vol. 83, no. 2, pp. 147-156, 2015.
26. W. Fenske, T. Athanasiou, L. Harling, C. Drechsler, A. Darzi, and H. Ashrafian, "Obesity-related cardiorenal disease: The benefits of bariatric surgery, " Nature Reviews Nephrology, vol. 9, no. 9, pp. 539-551, 2013.
27. S. P. J. Macdonald, S. F. Stone, C. L. Neil et al., "Sustained elevation of resistin, NGAL and IL-8 are associated with severe sepsis/septic shock in the emergency department, " PLoS ONE, vol. 9, no. 10 article e110678, 2014.
28. B. S. Fernandes, S. Dash, F. Jacka et al., "Leptin in bipolar disorder: A systematic review and meta-analysis, " European Psychiatry, vol. 35, pp. 1-7, 2016.
29. A. Koch, E. Sanson, S. Voigt, A. Helm, C. Trautwein, and F. Tacke, "Serumadiponectin upon admission to the intensive care unit may predict mortality in critically ill patients, " Journal of Critical Care, vol. 26, no. 2, pp. 166-174, 2011.
30. Y.-L. Tan, X.-L. Zheng, and C.-K. Tang, "The protective functions of omentin in cardiovascular diseases, " Clinica Chimica Acta, vol. 448, pp. 98-106, 2015.
31. A. Schäffler, M. Neumeier, H. Herfarth, A. Fürst, J. Schölmerich, and C. Büchler, "Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue, " Biochimica et BiophysicaActa-Gene Structure and Expression, vol. 1732, no. 1-3, pp. 96-102, 2005.
32. J.-K. Lee, J. Schnee, M. Pang et al., "Human homologs of the Xenopus oocyte cortical granule lectin XL35, " Glycobiology, vol. 11, no. 1, pp. 65-73, 2001.
33. L. Gerwick, G. Corley-Smith, and C. J. Bayne, "Gene transcript changes in individual rainbow trout livers following an inflammatory stimulus, " Fish and Shellfish Immunology, vol. 22, no. 3, pp. 157-171, 2007.
34. J. M. Moreno-Navarrete, V. Cataln, F. Ortega et al., "Circulating omentin concentration increases after weight loss, " Nutrition and Metabolism, vol. 7 article 27, 2010.
35. V. Katsi, G. Vamvakou, J. Lekakis et al., "Omentin, fat and heart: classical music with new instruments, " Heart Lung and Circulation, vol. 23, no. 9, pp. 802-806, 2014.
36. P. Poirier, T. D. Giles, G. A. Bray et al., "Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss, " Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 5, pp. 968-976, 2006.
37. X. Zhong, X. Li, F. Liu, H. Tan, and D. Shang, "Omentin inhibits TNF-induced expression of adhesion molecules in endothelial cells via ERK/NF-B pathway, " Biochemical and Biophysical Research Communications, vol. 425, no. 2, pp. 401-406, 2012.
38. Y. M. Arabi, S. I. Dara, H. M. Tamim et al., "Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: An International Multicenter Cohort Study, " Critical Care, vol. 17, no. 2, article R72, 2013.
39. R. N. Dickerson, "The obesity paradox in the ICU: real or not?" Critical Care, vol. 17, article 154, 2013.
40. S. M. A. Lobo, F. R. M. Lobo, D. P. Bota et al., "C-reactive protein levels correlate with mortality and organ failure in critically III patients, " Chest, vol. 123, no. 6, pp. 2043-2049, 2003.
41. N. Boussekey, O. Leroy, H. Georges, P. Devos, T. d'Escrivan, and B. Guery, "Diagnostic and prognostic values of admission procalcitonin levels in community-acquired pneumonia in an intensive care unit, " Infection, vol. 33, no. 4, pp. 257-263, 2005.
42. D. M. Griffith, M. E. Vale, C. Campbell, S. Lewis, andT. S. Walsh, "Persistent inflammation and recovery after intensive care: A systematic review, " Journal of Critical Care, vol. 33, pp. 192-199, 2016.
43. T. Akba, S. Karakurt, G. Nlgzel, T. Ç elikel, and S. Akalin, "The endocrinologic changes in critically ill chronic obstructive pulmonary disease patients, " COPD, vol. 7, no. 4, pp. 240-247, 2010.
44. S. S. Gülcher, N. A. Bruins, W. P. Kingma, and E. C. Boerma, "Elevated C-reactive protein levels at ICU discharge as a predictor of ICU outcome: A retrospective cohort study, " Annals of Intensive Care, vol. 6, article 5, 2016.
45. J.-L. Vincent, J.-C. Preiser, C. L. Sprung, R. Moreno, and Y. Sakr, "Insulin-treated diabetes is not associated with increased mortality in critically ill patients, " Critical Care, vol. 14, no. 1, article R12, 2010.