Distinct brain networks underlie cognitive dysfunction in Parkinson and Alzheimer diseases

Neurology

Volumn 87, Issue 18, 2016, Pages 1925-1933

  Mattis, Paul J ^a,b   Niethammer, Martin ^a,b   Sako, Wataru ^a   Tang, Chris C ^a   Nazem, Amir ^a   Gordon, Marc L ^a,b   Brandt, Vicky ^a   Dhawan, Vijay ^a   Eidelberg, David ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b Northwell Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; COGNITIVE DEFECT; COGNITIVE FUNCTION TEST; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; HIPPOCAMPUS; HUMAN; MALE; NERVOUS SYSTEM PARAMETERS; NEUROIMAGING; PARAHIPPOCAMPAL GYRUS; PARKINSON DISEASE; PARKINSON DISEASE COGNITION RELATED PATTERN; PARKINSON DISEASE MOTOR RELATED PATTERN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VERY ELDERLY; ANALYSIS OF VARIANCE; BRAIN; CASE CONTROL STUDY; COGNITION DISORDERS; COMPLICATION; DIAGNOSTIC IMAGING; METABOLISM; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PARKINSONISM; PSYCHOLOGICAL RATING SCALE; SEVERITY OF ILLNESS INDEX;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; BRAIN; CASE-CONTROL STUDIES; COGNITION DISORDERS; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PARKINSONIAN DISORDERS; POSITRON-EMISSION TOMOGRAPHY; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX;

EID: 84994102590     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000003285     Document Type: Article

References (31)

1. Aarsland D, Kurz MW. The epidemiology of dementia associated with Parkinson disease. J Neurol Sci 2010; 289:18-22.
2. Janvin CC, Larsen JP, Aarsland D, Hugdahl K. Subtypes of mild cognitive impairment in Parkinson's disease: progression to dementia. Mov Disord 2006;21:1343-1349.
3. Irwin DJ, White MT, Toledo JB, et al. Neuropathologic substrates of Parkinson disease dementia. Ann Neurol 2012;72:587-598.
4. Irwin DJ, Lee VM, Trojanowski JQ. Parkinson's disease dementia: convergence of alpha-synuclein, tau and amyloidbeta pathologies. Nat Rev Neurosci 2013;14:626-636.
5. Jellinger KA, Seppi K, Wenning GK, Poewe W. Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease. J Neural Transm 2002;109:329-339.
6. Compta Y, Parkkinen L, O'Sullivan SS, et al. Lewy-and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important? Brain 2011;134:1493-1505.
7. Habeck C, Foster N, Perneczky R, et al. Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease. Neuroimage 2008;40:1503-1515.
8. Scarmeas N, Habeck CG, Zarahn E, et al. Covariance PET patterns in early Alzheimer's disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performance. Neuroimage 2004;23:35-45.
9. Teune LK, Strijkert F, Renken RJ, et al. The Alzheimer's disease-related glucose metabolic brain pattern. Curr Alzheimer Res 2014;11:725-732.
10. Eidelberg D. Metabolic brain networks in neurodegenerative disorders: a functional imaging approach. Trends Neurosci 2009;32:548-557.
11. Niethammer M, Eidelberg D. Metabolic brain networks in translational neurology: concepts and applications. Ann Neurol 2012;72:635-647.
12. Feigin A, Leenders KL, Moeller JR, et al. Metabolic network abnormalities in early Huntington's disease: an [(18) F]FDG PET study. J Nucl Med 2001;42:1591-1595.
13. Tang CC, Feigin A, Ma Y, et al. Metabolic network as a progression biomarker of premanifest Huntington's disease. J Clin Invest 2013;123:4076-4088.
14. Mure H, Hirano S, Tang CC, et al. Parkinson's disease tremor-related metabolic network: characterization, progression, and treatment effects. Neuroimage 2011;54: 1244-1253.
15. Huang C, Mattis P, Tang C, Perrine K, Carbon M, Eidelberg D. Metabolic brain networks associated with cognitive function in Parkinson's disease. Neuroimage 2007;34: 714-723.
16. Mattis PJ, Tang CC, Ma Y, Dhawan V, Eidelberg D. Network correlates of the cognitive response to levodopa in Parkinson disease. Neurology 2011;77:858-865.
17. Meles SK, Tang CC, Teune LK, et al. Abnormal metabolic pattern associated with cognitive impairment in Parkinson's disease: a validation study. J Cereb Blood Flow Metab 2015;35:1478-1484.
18. Huang C, Mattis P, Perrine K, Brown N, Dhawan V, Eidelberg D. Metabolic abnormalities associated with mild cognitive impairment in Parkinson disease. Neurology 2008;70:1470-1477.
19. Spetsieris P, Ma Y, Peng S, et al. Identification of diseaserelated spatial covariance patterns using neuroimaging data. J Vis Exp 2013;76:e50319.
20. Spetsieris PG, Eidelberg D. Scaled subprofile modeling of resting state imaging data in Parkinson's disease: methodological issues. Neuroimage 2011;54:2899-2914.
21. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
22. Hughes A, Daniel S, Ben-Shlomo Y, Lees A. The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 2002;125:861-870.
23. Mattis S. Dementia Rating Scale: Professional Manual. Odessa: Psychological Assessment Resources; 1988.
24. Tang C, Poston K, Dhawan V, Eidelberg D. Abnormalities in metabolic network activity precede the onset of motor symptoms in Parkinson's disease. J Neurosci 2010;30:1049-1056.
25. Holtbernd F, Ma Y, Peng S, et al. Dopaminergic correlates of metabolic network activity in Parkinson's disease. Hum Brain Mapp 2015;36:3575-3585.
26. Niethammer M, Tang CC, Ma Y, et al. Parkinson's disease cognitive network correlates with caudate dopamine. Neuroimage 2013;78:204-209.
27. Crane PK, Carle A, Gibbons LE, et al. Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI). Brain Imaging Behav 2012;6:502-516.
28. Weintraub D, Dietz N, Duda JE, et al. Alzheimer's disease pattern of brain atrophy predicts cognitive decline in Parkinson's disease. Brain 2012;135:170-180.
29. Davatzikos C, Genc A, Xu D, Resnick SM. Voxel-based morphometry using the RAVENS maps: methods and validation using simulated longitudinal atrophy. Neuroimage 2001;14:1361-1369.
30. Spetsieris PG, Ko JH, Tang CC, et al. Metabolic restingstate brain networks in health and disease. Proc Natl Acad Sci U S A 2015;112:2563-2568.
31. Schmahmann JD, Doyon J, Toga AW, Petrides M, Evans AC. MRI Atlas of the Human Cerebellum. San Diego: Academic Press; 2000.