First report of Escherichia coli co-producing NDM-1 and OXA-232

Diagnostic Microbiology and Infectious Disease

Volumn 86, Issue 4, 2016, Pages 437-438

  Both, Anna ^a   Huang, Jiabin ^a   Kaase, Martin ^b   Hezel, Julia ^c   Wertheimer, Daniel ^c   Fenner, Ines ^d   Günther, Thomas ^e   Grundhoff, Adam ^e   Büttner, Henning ^a   Aepfelbacher, Martin ^a   Rohde, Holger ^a   Hentschke, Moritz ^d  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c Schon Klinik Hamburg Eilbek   (Germany)

^d MVZ Labor Dr Fenner und Kollegen   (Germany)

^e LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

Carbapenemase; Co production; NDM 1; OXA 232

Indexed keywords

AMINOGLYCOSIDE; BACTERIAL DNA; BETA LACTAM; CARBAPENEM; CARBAPENEMASE; CEFTRIAXONE; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; COLISTIN; COTRIMOXAZOLE; IMIPENEM; MEROPENEM; NDM 1 ENZYME; OXA 232 ENZYME; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TIGECYCLINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA LACTAMASE;

AGED; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; ASPIRATION PNEUMONIA; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATION; CASE REPORT; CEREBROVASCULAR ACCIDENT; DNA EXTRACTION; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE IDENTIFICATION; GENE LOCATION; HOSPITALIZATION; HUMAN; INGUINAL SWAB; KLEBSIELLA PNEUMONIAE; LUNG BIOPSY; MEDICAL HISTORY; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; NDM 1 GENE; NONHUMAN; NOSE SMEAR; OXA 232 GENE; PATIENT TRANSPORT; PLASMID; PNEUMONIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SMEAR; THROAT CULTURE; TRACHEOTOMY; TREATMENT DURATION; UNCONSCIOUSNESS; URINARY TRACT INFECTION; ANALYSIS; DNA SEQUENCE; ENZYMOLOGY; ESCHERICHIA COLI INFECTION; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; SECRETION (PROCESS);

AGED; BACTERIAL PROTEINS; BETA-LACTAMASES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GENOTYPE; HUMANS; MALE; PLASMIDS; SEQUENCE ANALYSIS, DNA;

EID: 84994048704     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2016.09.005     Document Type: Article

References (11)

1. Al-Marzooq, F., Ngeow, Y.F., Tay, S.T., Emergence of Klebsiella pneumoniae producing dual carbapenemases (NDM-1 and OXA-232) and 16S rRNA methylase (armA) isolated from a Malaysian patient returning from India. Int J Antimicrob Agents 45 (2015), 445–446.
2. OXA-232-carrying Klebsiella pneumoniae and its probable cross-transmission in a French hospital. Int J Antimicrob Agents 44 (2014), 469–470.
3. Bush, K., A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant gram-negative pathogens. Int J Antimicrob Agents 46 (2015), 483–493.
4. Doi, Y., O'Hara, J.A., Lando, J.F., Querry, A.M., Townsend, B.M., Pasculle, A.W., et al. Co-production of NDM-1 and OXA-232 by Klebsiella pneumoniae. Emerg Infect Dis 20 (2014), 163–165.
5. Doi, Y., Hazen, T.H., Boitano, M., Tsai, Y.-C., Clark, T.A., Korlach, J., et al. Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing. Antimicrob Agents Chemother 58 (2014), 5947–5953.
6. Falcone, M., Paterson, D.L., Spotlight on ceftazidime/avibactam: a new option for MDR gram-negative infections. J Antimicrob Chemother, 2016 [Epub ahead of print].
7. Kwon, T., Yang, J.W., Lee, S., Yun, M.-R., Yoo, W.G., Kim, H.S., et al. Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae KP617, coproducing OXA-232 and NDM-1 carbapenemases, isolated in South Korea. Genome Announc, 4, 2016.
8. Meletis, G., Chatzidimitriou, D., Malisiovas, N., Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade. Eur J Clin Microbiol Infect Dis 34 (2015), 1487–1493.
9. Potron, A., Rondinaud, E., Poirel, L., Belmonte, O., Boyer, S., Camiade, S., et al. Genetic and biochemical characterisation of OXA-232, a carbapenem-hydrolysing class D β-lactamase from enterobacteriaceae. Int J Antimicrob Agents 41 (2013), 325–329.
10. Queenan, A.M., Bush, K., Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev 20 (2007), 440–458.
11. Zankari, E., Hasman, H., Cosentino, S., Vestergaard, M., Rasmussen, S., Lund, O., et al. Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother 67 (2012), 2640–2644.