-
2
-
-
78650303860
-
Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study
-
Cavo M. Tacchetti P. Patriarca F. Petrucci M.T. Pantani L. Galli M. et al. (2010) Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet 376: 2075–2085.
-
(2010)
Lancet
, vol.376
, pp. 2075-2085
-
-
Cavo, M.1
Tacchetti, P.2
Patriarca, F.3
Petrucci, M.T.4
Pantani, L.5
Galli, M.6
-
3
-
-
78049488759
-
Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial
-
Harousseau J.L. Attal M. Avet-Loiseau H. Marit G. Caillot D. Mohty M. et al. (2010) Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol 28: 4621–4629.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4621-4629
-
-
Harousseau, J.L.1
Attal, M.2
Avet-Loiseau, H.3
Marit, G.4
Caillot, D.5
Mohty, M.6
-
6
-
-
79960666079
-
Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1 / 2 Multiple Myeloma Research Consortium trial
-
Jakubowiak A.J. Griffith K.A. Reece D.E. Hofmeister C.C. Lonial S. Zimmerman T.M. et al. (2011) Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1 / 2 Multiple Myeloma Research Consortium trial. Blood 118: 535–543.
-
(2011)
Blood
, vol.118
, pp. 535-543
-
-
Jakubowiak, A.J.1
Griffith, K.A.2
Reece, D.E.3
Hofmeister, C.C.4
Lonial, S.5
Zimmerman, T.M.6
-
8
-
-
77957344540
-
Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial
-
Mateos M.V. Oriol A. Martinez-Lopez J. Gutierrez N. Teruel A.I. de Paz R. et al. (2010) Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncol 11: 934–941.
-
(2010)
Lancet Oncol
, vol.11
, pp. 934-941
-
-
Mateos, M.V.1
Oriol, A.2
Martinez-Lopez, J.3
Gutierrez, N.4
Teruel, A.I.5
de Paz, R.6
-
9
-
-
0030593939
-
Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway
-
Mitch W.E. Goldberg A.L. (1996) Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. N Engl J Med 335: 1897–1905.
-
(1996)
N Engl J Med
, vol.335
, pp. 1897-1905
-
-
Mitch, W.E.1
Goldberg, A.L.2
-
10
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
-
Mitsiades N. Mitsiades C.S. Richardson P.G. Poulaki V. Tai Y.T. Chauhan D. et al. (2003) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101: 2377–2380.
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
Poulaki, V.4
Tai, Y.T.5
Chauhan, D.6
-
11
-
-
57349171505
-
Prospective comparison of subcutaneous versus intravenous administration of bortezomib in patients with multiple myeloma
-
Moreau P. Coiteux V. Hulin C. Leleu X. van de Velde H. Acharya M. et al. (2008) Prospective comparison of subcutaneous versus intravenous administration of bortezomib in patients with multiple myeloma. Haematologica 93: 1908–1911.
-
(2008)
Haematologica
, vol.93
, pp. 1908-1911
-
-
Moreau, P.1
Coiteux, V.2
Hulin, C.3
Leleu, X.4
van de Velde, H.5
Acharya, M.6
-
12
-
-
79955461011
-
Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study
-
Moreau P. Pylypenko H. Grosicki S. Karamanesht I. Leleu X. Grishunina M. et al. (2011) Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study. Lancet Oncol 12: 431–440.
-
(2011)
Lancet Oncol
, vol.12
, pp. 431-440
-
-
Moreau, P.1
Pylypenko, H.2
Grosicki, S.3
Karamanesht, I.4
Leleu, X.5
Grishunina, M.6
-
13
-
-
34548539381
-
Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression
-
Orlowski R.Z. Nagler A. Sonneveld P. Blade J. Hajek R. Spencer A. et al. (2007) Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol 25: 3892–3901.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3892-3901
-
-
Orlowski, R.Z.1
Nagler, A.2
Sonneveld, P.3
Blade, J.4
Hajek, R.5
Spencer, A.6
-
15
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-kappa B 1 precursor protein and the activation of NF-kappa B
-
Palombella V.J. Rando O.J. Goldberg A.L. Maniatis T. (1994) The ubiquitin-proteasome pathway is required for processing the NF-kappa B 1 precursor protein and the activation of NF-kappa B. Cell 78: 773–785.
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
16
-
-
78650993336
-
Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib–melphalan–prednisone for initial treatment of multiple myeloma: a randomized controlled trial
-
Palumbo A. Bringhen S. Rossi D. Cavalli M. Larocca A. Ria R. et al. (2010) Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib–melphalan–prednisone for initial treatment of multiple myeloma: a randomized controlled trial. J Clin Oncol 28: 5101–5109.
-
(2010)
J Clin Oncol
, vol.28
, pp. 5101-5109
-
-
Palumbo, A.1
Bringhen, S.2
Rossi, D.3
Cavalli, M.4
Larocca, A.5
Ria, R.6
-
18
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson P.G. Barlogie B. Berenson J. Singhal S. Jagannath S. Irwin D. et al. (2003) A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348: 2609–2617.
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
-
19
-
-
35148825003
-
Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial
-
Richardson P.G. Sonneveld P. Schuster M. Irwin D. Stadtmauer E. Facon T. et al. (2007) Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial. Blood 110: 3557–3560.
-
(2007)
Blood
, vol.110
, pp. 3557-3560
-
-
Richardson, P.G.1
Sonneveld, P.2
Schuster, M.3
Irwin, D.4
Stadtmauer, E.5
Facon, T.6
-
21
-
-
73349115580
-
Multicenter, phase I., dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed / refractory multiple myeloma
-
Richardson P.G. Weller E. Jagannath S. Avigan D.E. Alsina M. Schlossman R.L. et al. (2009) Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed / refractory multiple myeloma. J Clin Oncol 27: 5713–5719.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5713-5719
-
-
Richardson, P.G.1
Weller, E.2
Jagannath, S.3
Avigan, D.E.4
Alsina, M.5
Schlossman, R.L.6
-
22
-
-
77954618168
-
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
-
Richardson P.G. Weller E. Lonial S. Jakubowiak A.J. Jagannath S. Raje N.S. et al. (2010) Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 116: 679–686.
-
(2010)
Blood
, vol.116
, pp. 679-686
-
-
Richardson, P.G.1
Weller, E.2
Lonial, S.3
Jakubowiak, A.J.4
Jagannath, S.5
Raje, N.S.6
-
23
-
-
79957974678
-
A phase III PETHEMA / GEM study of induction therapy prior autologous stem cell transplantation (ASCT) in multiple myeloma: superiority of VTD (bortezomib/thalidomide/dexamethasone) over TD and VBMCP / VBAD plus bortezomib
-
Rosinol L. Cibeira M.T. Mateos M.V. Martinez J. Oriol A. Teruel A.I. et al. (2010) A phase III PETHEMA / GEM study of induction therapy prior autologous stem cell transplantation (ASCT) in multiple myeloma: superiority of VTD (bortezomib/thalidomide/dexamethasone) over TD and VBMCP / VBAD plus bortezomib. ASH Annual Meeting Abstracts 116 (21): 307.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, Issue.21
, pp. 307
-
-
Rosinol, L.1
Cibeira, M.T.2
Mateos, M.V.3
Martinez, J.4
Oriol, A.5
Teruel, A.I.6
-
25
-
-
79952790841
-
HOVON-65/GMMG-HD4 randomized phase III trial comparing bortezomib, doxorubicin, dexamethasone (PAD) vs VAD followed by high-dose melphalan (HDM) and maintenance with bortezomib or thalidomide in patients with newly diagnosed multiple myeloma (MM)
-
Sonneveld P. Schmidt-Wolf I. van der Holt B. Jarari L.E. Bertsch U. Salwender H. et al. (2010) HOVON-65/GMMG-HD4 randomized phase III trial comparing bortezomib, doxorubicin, dexamethasone (PAD) vs VAD followed by high-dose melphalan (HDM) and maintenance with bortezomib or thalidomide in patients with newly diagnosed multiple myeloma (MM). ASH Annual Meeting Abstracts 116 (21): 40.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, Issue.21
, pp. 40
-
-
Sonneveld, P.1
Schmidt-Wolf, I.2
van der Holt, B.3
Jarari, L.E.4
Bertsch, U.5
Salwender, H.6
|