The M Cell

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 2, Issue 1, 1997, Pages 73-76

  Antzelevitch, Charles ^a  

^a MASONIC MEDICAL RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84992812966     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/107424849700200109     Document Type: Editorial

References (26)

1. Lukas A. Electrophysiology of myocardial cells in the epicardial, midmyocardial, and endocardial layers of the ventricle. J Cardiovasc Pharmacol Therapeut 2: 61, 1997
2. Sicouri S., Moro S., Elizari MV d-Sotalol induces marked action potential prolongation and early afterdepolarizations in M but not epicardial or endocardial cells of the canine ventricle. J Cardiovasc Pharmacol Therapeut 2: 27, 1997
3. Sicouri S., Antzelevitch C. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: the M cell. Circ Res 68: 1729, 1991
4. Antzelevitch C., Sicouri S., Litovsky SH, et al. Heterogeneity within the ventricular wall: electrophysiology and pharmacology of epicardial, endocardial and M cells. Circ Res 69: 1427, 1991
5. Anyukhovsky EP, Sosunov EA, Rosen MR Regional differences in electrophysiologic properties of epicardium, midmyocardium and endocardium: in vitro and in vivo correlations. Circulation 1996 94: 1981, 1996
6. Liu DW, Antzelevitch C. Characteristics of the delayed rectifier current (IKr and I Ks) in canine ventricular epicardial, midmyocardial and endocardial myocytes: a weaker IKs contributes to the longer action potential of the M cell. Circ Res 76: 351, 1995
7. Eddlestone GT, Zygmunt AC, Antzelevitch C. Larger late sodium current contributes to the longer action potential of the M cell in canine ventricular myocardium. PACE 19: II-569(Abstract), 1996
8. Burashnikov A., Antzelevitch C. α-Agonists produce opposite effect on action potential duration in Purkinje and M cells isolated from the canine left ventricle. PACE 18: II-935(Abstract), 1995
9. Burashnikov A., Antzelevitch C. Mechanisms underlying early afterdepolarization activity are different in canine purkinje and M cell preparations. Role of intracellular calcium. Circulation 94: I-527(Abstract), 1996
10. Liu DW, Gintant GA, Antzelevitch C. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial. and endocardial myocytes from the free wall of the canine left ventricle. Circ Res 72: 671, 1993
11. Lukas A., Antzelevitch C. Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia: Role of the transient outward current. Circulation 88: 2903, 1993
12. Antzelevitch C., Sun ZQ, Zhang ZQ, Yan GX Cellular and ionic mechanisms underlying erythromycin-induced long QT and torsade de pointes. J Am Coll Cardiol 28: 1836, 1996
13. Yan GX, Antzelevitch C. Delayed repolarization of M cells underlies the manifestation of U waves, notched T waves and long QT intervals in the electrocardiogram (ECG). Circulation 92: I-480(Abstract), 1995
14. Weissenburger J., Nesterenko VV, Antzelevitch C. Intramural monophasic action potentials (MAP) display steeper APD-rate relations and higher sensitivity to class III agents than epicardial and endocardial MAPs: characteristics of the M cell in vivo. Circulation 92: I-300 (Abstract), 1995
15. Weissenburger J., Nesterenko VV, Antzelevitch C. M cells contribute to transmural dispersion of repolarization and to the development of torsade de pointes in the canine heart in vivo. PACE 19: II-707(Abstract), 1996
16. EI-Sherif NC, Restivo M. The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome: tridimensional mapping of activation and recovery patterns. Circ Res 79: 474, 1996
17. Plonsey R. Action potential sources and their volume conductor fields. Proc IEEE 65: 601, 1977
18. Spach MS, Barr RC, Serwer GA, Kootsey JM, Johnson EA Extracellular potentials related to intracellular action potentials in the dog Purkinje system. Circ Res 30: 505, 1972
19. Friegang KD, Becker R., Bauer A., Voss F., Senges J., Brachmann J.: Electrophysiological properties of individual muscle layers in the in vivo canine heart. J Am Coll Cardiol 27(supplA):124A(Abstract) 1996
20. Sosunov EA, Anyukhovsky EP, Rosen MR Comparison of repolarization of cells from different layers of myocardium in vitro and in vivo. Biophys J 70, No.2 (Pt.2):A276 (Abstract) 1996
21. Duker GD, Linhardt GS, Rahmberg M. An animal model for studying class III-induced proarrhythmias in the halothane-anesthetized dog. J Am Coll Cardiol 23: 326A (Abstract) 1994
22. Burgess MJ, Green LS, Millar K., Wyatt RF, Abildskov JA The sequence of normal ventricular recovery. Am Heart J 84: 660, 1972
23. Watanabe Y. Purkinje repolarization as a possible cause of the U wave in the electrocardiogram. Circulation 51: 1030, 1975
24. Antzelevitch C., Nesterenko VV, Yan GX: The role of M cells in acquired long QT syndrome, U waves, and torsade de pointes. J Electrocardiol 28(suppl.):131, 1996
25. Chauhan VS, Skanes AC, Tang Asl. Dynamics and dispersion of QT intervals: Q-wave versus non Q-wave myocardial infarction. Circulation 94: I-433(Abstract) 1996
26. Yan GX, Antzelevitch C. Cellular basis for the electrocardiographic J wave. Circulation 93: 372, 1996