Occurrence of Foreign Body Rhinitis in F344 Rats During Toxicologic Studies

Journal of Toxicologic Pathology

Volumn 10, Issue 1, 1997, Pages 25-29

  Takeuchi, Tetsuya ^a   Nagano, Kasuke ^a   Aiso, Shigetoshi ^a   Katagiri, Taku ^a   Okudaira, Masahiko ^a   Fujiwara, Kosaku ^b  

^a Japan Bioassay Research Center   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

Aging; Animal hair; F344 rat; Foreign body; Nasal mucosa; Rhinitis

Indexed keywords

EID: 84992535308     PISSN: 09149198     EISSN: None     Source Type: Journal    
DOI: 10.1293/tox.10.25     Document Type: Article

References (22)

1. Boorman GA, Morgan KT, and Uraih LC. Nose, larynx and trachea. In: Pathology of the Fischer rat. Boorman GA, Eustis SL, Elwell MR, Montgomery CA Jr., MacKenzie WF, eds, San Diego: Academic Press, 1990.
2. Clair MBG St, and Morgan KT. Changes in the upper respiratory tract. In : Pathobiology of the aging rat, Vol. 1, Mohr U, Dungworth DL, Capen CC eds. Washington: ILSI Press, 1992.
3. Monticello TM, Morgan KT, and Uraih L. Nonneoplastic nasal lesions in rats and mice. Environ Health Perspect 1990; 85 : 249-74.
4. Coleman GL, Barthold SW, Osbaldiston GW, Foster SJ, and Jonas AM. Pathological changes during aging in barrier-reared Fischer 344 male rats. J Gerontol 1977 ; 32 : 258-78.
5. Goodman DG, Ward JM, Squire RA, Chu KC, and Linhart MS. Neoplastic and nonneoplastic lesions in aging F344 rats. Toxicol Appl Pharmacol 1979 ; 48 : 237-48.
6. Iwata H, Hirouchi Y, Choice Y, Yamakawa S, Kobayashi K, Yamamoto T, Kobayashi K, Inoue H, and Enomoto M. Historical control data of non-neoplastic and neoplastic lesions in F344/DuCrj rats. J Toxicol Pathol 1991; 4: 1-24.
7. Rehm S, Waalkes MP, and Ward JM. Aspergillus rhinitis in Wistar (Crl: (WI) BR) rats. Lab Anim Sci 1988 ; 38: 162-6.
8. Nagano K, Enomoto M, Yamanouchi K, Aiso S, Katagiri T, and Matumoto M. Toxicologic pathology of upper respiratory tract (in Japanese). J Toxicol Pathol 1988 ; 1: 115-27.
9. Kuboyama Y, Mori K, Suzuki K, Ishii A, and Shuto K. Changes in nasal cavity volume and target area of exposure to nasal drops with age in rats. Exp Anim 1996 ; 45 : 15-22.
10. Proctor DF and Chang JCF. Comparative anatomy and physiology of the nasal cavity. In : Nasal tumors in animals and man, vol. 1, Reznick G, Sherman FS, eEds, Florida: CRC Press, 1983.
11. Morgan KT and Monticello TM. Airflow, gas deposition, and lesion distribution in the nasal passages. Environ Health Perspect 1990; 88 : 209-18.
12. Reznik GK. Comparative anatomy, physiology, and function of the upper respiratory tract. Environ Health Perspect 1990; 85: 171-76.
13. Gaskell BA. Nonneoplastic changes in the olfactory epithelium : experimental studies. Environ Health Perspect 1990; 85: 275-89.
14. Gross EA, Patterson DL, and Morgan KT. Effects of acute and chronic dimethylamine exposure on the nasal mucociliary apparatus of F-344 rats. Toxicol Appl Pharmacol 1987 ; 90 : 359-76.
15. Kerns WD, Pavkov KL, Donofrio DJ, Gralla EJ, and Swenberg JA. Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure. Cancer Res 1983 ; 43: 4382-92.
16. Hurtt ME, Thomas DA, Working PK, Monticello TM, and Morgan KT. Degeneration and regeneration of the olfactory epithelium following inhalation exposure to methyl bromide: pathology, cell kinetics, and olfactory function. Toxicol Appl Pharmacol 1988; 94: 311-28.
17. Appelman LM, Woutersen RA, and Feron VJ. Inhalation toxicity of acetaldehyde in rats. I. Acute and subacute studies. Toxicology 1982 ; 23 : 293-307.
18. Woutersen RA, Appelman LM, Feron VJ, and Van Der Heijden CA. Inhalation toxicity of acetaldehyde in rats. II. Carcinogenicity study : Interim results after 15 months. Toxicology 1984; 31: 123-33.
19. Buckley LA, Morgan KT, Swenberg JA, James RA, Hamm TE, and Barrow CS. The toxicity of dimethylamine in F-344 rats and B6C3F1 mice following a 1-year inhalation exposure. Fund Appl Toxicol 1985; 5: 341-52.
20. Dunnick JK, Eustis SL, Piegorsch WW, and Miller RA. Respiratory tract lesions in F344/N rats and B6C3F1 mice after inhalation exposure to 1,2-epoxybutane. Toxicology 1988; 50: 69-82.
21. Feron VJ, Kruysse A, Til HP, and Immel HR. Repeated exposure to acrolein vapour: subacute studies in hamsters, rats and rabbits. Toxicology 1978 ; 9 : 47-57.
22. Jiang XZ, Buckley LA, and Morgan KT. Pathology of toxic responses to the RD50 concentration of chlorine gas in the nasal passages of rats and mice. Toxicol Appl Pharmacol 1983 ; 71: 225-36.