Electroacupuncture at acupoint ST 37(Shangjuxu) improves function of the enteric nervous system in a novel mouse constipation model

BMC Complementary and Alternative Medicine

Volumn 16, Issue 1, 2016, Pages

  Liang, Chao ^a   Wang, Kaiyue ^b   Xu, Bin ^a   Yu, Zhi ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Xi'an Traditional Chinese Medicine Hospital   (China)

Author keywords

Electroacupuncture(EA); Enteric nervous system(ENS); Gastrointestinal (GI); Neuronal nitric oxide synthase (nNOS)

Indexed keywords

CELL PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; PROTEIN GENE PRODUCT 9.5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; C57BL 6 MOUSE; CONSTIPATION; CONTROLLED STUDY; DEFECATION; ELECTROACUPUNCTURE; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINE INNERVATION; INTESTINE MOTILITY; JEJUNUM; MALE; MOUSE; MOUSE MODEL; MYENTERIC PLEXUS; NONHUMAN; PROTEIN EXPRESSION; THERAPY EFFECT; TIME; TREATMENT DURATION; ACUPUNCTURE; ANIMAL; C57BL MOUSE; CHEMISTRY; DISEASE MODEL; GASTROINTESTINAL MOTILITY; INTESTINE; METABOLISM; PHYSIOLOGY; PROCEDURES;

ACUPUNCTURE POINTS; ANIMALS; CONSTIPATION; DISEASE MODELS, ANIMAL; ELECTROACUPUNCTURE; GASTROINTESTINAL MOTILITY; INTESTINES; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE I;

EID: 84992445360     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1377-5     Document Type: Article

References (38)

1. Park HJ, Jarrett M, Cain K, Heitkemper M. Psychological distress and GI symptoms are related to severity of bloating in women with irritable bowel syndrome. Res Nurs Health. 2008;31(2):98-107.
2. Choung RS, Locke GR 3rd, Zinsmeister AR, Schleck CD, Talley NJ. Psychosocial distress and somatic symptoms in community subjects with irritable bowel syndrome: a psychological component is the rule. Am J Gastroenterol. 2009;104(7):1772-9.
3. Bittencourt AF, Martins JR, Logullo L, Shiroma G, Horie L, Ortolani MC, et al. Constipation is more frequent than diarrhea in patients fed exclusively by enteral nutrition: results of an observational study. Nutr Clin Pract. 2012;27(4):533-9.
4. Na JR, Oh KN, Park SU, Bae D, Choi EJ, Jung MA, et al. The laxative effects of Maesil (Prunus mume Siebold & Zucc.) on constipation induced by a low-fibre diet in a rat model. Int J Food Sci Nutr. 2013;64(3):333-45.
5. McCarberg BH. Overview and treatment of opioid-induced constipation. Postgrad Med. 2013;125(4):7-17.
6. Chiarelli P, Brown W, McElduff P. Constipation in Australian women: prevalence and associated factors. Int Urogynecol J Pelvic Floor Dysfunct. 2000;11(2):71-8.
7. Liu Z, Liu J, Zhao Y, Cai Y, He L, Xu H, et al. The efficacy and safety study of electro-acupuncture for severe chronic functional constipation: study protocol for a multicenter, randomized, controlled trial. Trials. 2013;14:176.
8. Xiong F, Wang Y, Li SQ, Tian M, Zheng CH, Huang GY. Clinical study of electro-acupuncture treatment with different intensities for functional constipation patients. J Huazhong Univ Sci Technolog Med Sci. 2014;34(5):775-81.
9. Xu X, Zheng C, Zhang M, Wang W, Huang G. A randomized controlled trial of acupuncture to treat functional constipation: design and protocol. BMC Complement Altern Med. 2014;14:423.
10. Chen DP, Xiong YJ, Tang ZY, Yao QY, Ye DM, Liu SS, et al. Characteristics of deslanoside-induced modulation on jejunal contractility. World J Gastroenterol. 2012;18(41):5889-96.
11. Yang X, Xi TF, Li YX, Wang HH, Qin Y, Zhang JP, et al. Oxytocin decreases colonic motility of cold water stressed rats via oxytocin receptors. World J Gastroenterol. 2014;20(31):10886-94.
12. Zhu X, Liu Z, Qu H, Niu W, Gao L, Wang Y, et al. The effect and mechanism of electroacupuncture at LI11 and ST37 on constipation in a rat model. Acupunct Med. 2016;34(3):194-200.
13. Qin QG, Gao XY, Liu K, Yu XC, Li L, Wang HP, et al. Acupuncture at heterotopic acupoints enhances jejunal motility in constipated and diarrheic rats. World J Gastroenterol. 2014;20(48):18271-8.
14. Inanç BB. A new theory on the evaluation of traditional chinese acupuncture mechanisms from the latest medical scientific point of view. Acupunct Electrother Res. 2015;40(3):189-204.
15. Fabrin S, Soares N, Pezarezi Yoshimura D, Hallak Regalo SC, Donizetti Verri E, de Freitas Vianna JR, et al. Effects of acupuncture at the Yintang and the Chengjiang acupoints on cardiac arrhythmias and neurocardiogenic syncope in emergency first aid. J Acupunct Meridian Stud. 2016;9(1):26-30.
16. Zhao C, Bao C, Li J, Zhu Y, Wang S, Yang L, et al. Moxibustion and acupuncture ameliorate Crohn's disease by regulating the balance between Th17 and Treg cells in the intestinal mucosa. Evid Based Complement Alternat Med. 2015;2015:938054.
17. Iwa M, Matsushima M, Nakade Y, Pappas TN, Fujimiya M, Takahashi T. Electroacupuncture at ST-36 accelerates colonic motility and transit in freely moving conscious rats. Am J Physiol Gastrointest Liver Physiol. 2006;290(2):G285-92.
18. Liang C, Wang KY, Yu Z, Xu B. Development of a novel mouse constipation model. World J Gastroenterol. 2016;22(9):2799-810.
19. Wang SJ, Yang HY, Xu GS. Acupuncture alleviates colorectal hypersensitivity and correlates with the regulatory mechanism of TrpV1 and p-ERK. Evid Based Complement Alternat Med. 2012;2012:483123.
20. Li Y, Zheng H, Zeng F, Zhou SY, Zhong F, Zheng HB, et al. Use acupuncture to treat functional constipation: study protocol for a randomized controlled trial. Trials. 2012;13:104.
21. Sun JH, Wu XL, Xia C, Xu LZ, Pei LX, Li H, et al. Clinical evaluation of Soothing Gan and invigorating Pi acupuncture treatment on diarrhea-predominant irritable bowel syndrome. Chin J Integr Med. 2011;17(10):780-5.
22. MacPherson H, Bland M, Bloor K, Cox H, Geddes D, Kang'ombe A, et al. Acupuncture for irritable bowel syndrome: a protocol for a pragmatic randomised controlled trial. BMC Gastroenterol. 2010;10:63.
23. Kaptchuk TJ. Acupuncture: theory, efficacy, and practice. Ann Intern Med. 2002;136(5):374-83.
24. Tada H, Fujita M, Harris M, Tatewaki M, Nakagawa K, Yamamura T, et al. Neural mechanism of acupuncture-induced gastric relaxations in rats. Dig Dis Sci. 2003;48(1):59-68.
25. Zhenzhong L, Xiaojun Y, Weijun T, Yuehua C, Jie S, Jimeng Z, et al. Comparative effect of electroacupuncture and moxibustion on the expression of substance P and vasoactive intestinal peptide in patients with irritable bowel syndrome. J Tradit Chin Med. 2015;35(4):402-10.
26. Chen CY, Ke MD, Kuo CD, Huang CH, Hsueh YH, Chen JR. The influence of electro-acupuncture stimulation to female constipation patients. Am J Chin Med. 2013;41(2):301-13.
27. Noguchi E. Acupuncture regulates gut motility and secretion via nerve reflexes. Auton Neurosci. 2010;156(1-2):15-8.
28. Li YQ, Zhu B, Rong PJ, Ben H, Li YH. Neural mechanism of acupuncture-modulated gastric motility. World J Gastroenterol. 2007;13(5):709-16.
29. Furness JB. The enteric nervous system and neurogastroenterology. Nat Rev Gastroenterol Hepatol. 2012;9(5):286-94.
30. Heanue TA, Pachnis V. Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies. Nat Rev Neurosci. 2007;8(6):466-79.
31. Furness JB, Callaghan BP, Rivera LR, Cho HJ. The enteric nervous system and gastrointestinal innervation: integrated local and central control. Adv Exp Med Biol. 2014;817:39-71.
32. Sidebotham EL, Woodward MN, Kenny SE, Lloyd DA, Vaillant CR, Edgar DH. Assessment of protein gene product 9.5 as a marker of neural crest-derived precursor cells in the developing enteric nervous system. Pediatr Surg Int. 2001;17(4):304-7.
33. Du F, Wang L, Qian W, Liu S. Loss of enteric neurons accompanied by decreased expression of GDNF and PI3K/Akt pathway in diabetic rats. Neurogastroenterol Motil. 2009;21(11):1229-e114.
34. Matsuda NM, Miller SM, Evora PR. The chronic gastrointestinal manifestations of Chagas disease. Clinics (Sao Paulo). 2009;64(12):1219-24.
35. Di Nardo G, Blandizzi C, Volta U, Colucci R, Stanghellini V, Barbara G, et al. Review article: molecular, pathological and therapeutic features of human enteric neuropathies. Aliment Pharmacol Ther. 2008;28(1):25-42.
36. Wedel T, Roblick U, Gleiss J, Ott V, Eggers R, Kühnel W, et al. Disorders of intestinal innervation as a possible cause for chronic constipation. Zentralbl Chir. 1999;124(9):796-803.
37. Boeckxstaens GE, Hirsch DP, Kodde A, Moojen TM, Blackshaw A, Tytgat GN, et al. Activation of an adrenergic and vagally-mediated NANC pathway in surgery-induced fundic relaxation in the rat. Neurogastroenterol Motil. 1999;11(6):467-74.
38. Lies B, Beck K, Keppler J, Saur D, Groneberg D, Friebe A. Nitrergic signalling via interstitial cells of Cajal regulates motor activity in murine colon. J Physiol. 2015;593(20):4589-601.