메뉴 건너뛰기




Volumn 50, Issue 5-6, 2016, Pages 349-354

Platelet inhibition and bleeding complications in cardiac surgery: A review

Author keywords

bleeding; cardiac surgery; platelet inhibition; Platelets

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y RECEPTOR ANTAGONIST; TICLOPIDINE;

EID: 84992411638     PISSN: 14017431     EISSN: 16512006     Source Type: Journal    
DOI: 10.1080/14017431.2016.1231935     Document Type: Review
Times cited : (13)

References (49)
  • 1
    • 7944231168 scopus 로고    scopus 로고
    • Coagulation disorders of cardiopulmonary bypass: a review
    • Paparella D, Brister SJ, Buchanan MR. Coagulation disorders of cardiopulmonary bypass:a review. Intensive Care Med. 2004;30:1873–1881.
    • (2004) Intensive Care Med , vol.30 , pp. 1873-1881
    • Paparella, D.1    Brister, S.J.2    Buchanan, M.R.3
  • 2
    • 84899982955 scopus 로고    scopus 로고
    • Universal definition of perioperative bleeding in adult cardiac surgery
    • Dyke C, Aronson S, Dietrich W, et al. Universal definition of perioperative bleeding in adult cardiac surgery. J Thorac Cardiovasc Surg. 2014;147:1458–1463.e1.
    • (2014) J Thorac Cardiovasc Surg , vol.147 , pp. 1458-1463
    • Dyke, C.1    Aronson, S.2    Dietrich, W.3
  • 3
    • 84858306098 scopus 로고    scopus 로고
    • Impact of major bleeding and blood transfusions after cardiac surgery: analysis from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial
    • Stone GW, Clayton TC, Mehran R, et al. Impact of major bleeding and blood transfusions after cardiac surgery:analysis from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial. Am Heart J. 2012;163:522–529.
    • (2012) Am Heart J , vol.163 , pp. 522-529
    • Stone, G.W.1    Clayton, T.C.2    Mehran, R.3
  • 4
    • 84872277113 scopus 로고    scopus 로고
    • The association of blood transfusion with mortality after cardiac surgery: cause or confounding? (CME)
    • Dixon B, Santamaria JD, Reid D, et al. The association of blood transfusion with mortality after cardiac surgery:cause or confounding? (CME). Transfusion. 2013;53:19–27.
    • (2013) Transfusion , vol.53 , pp. 19-27
    • Dixon, B.1    Santamaria, J.D.2    Reid, D.3
  • 5
    • 53849129940 scopus 로고    scopus 로고
    • Surgical reexploration after cardiac operations: why a worse outcome?
    • Ranucci M, Bozzetti G, Ditta A, et al. Surgical reexploration after cardiac operations:why a worse outcome? Ann Thorac Surg. 2008;86:1557–1562.
    • (2008) Ann Thorac Surg , vol.86 , pp. 1557-1562
    • Ranucci, M.1    Bozzetti, G.2    Ditta, A.3
  • 6
    • 79957742227 scopus 로고    scopus 로고
    • Morbidity of bleeding after cardiac surgery: is it blood transfusion, reoperation for bleeding, or both?
    • Vivacqua A, Koch CG, Yousuf AM, et al. Morbidity of bleeding after cardiac surgery:is it blood transfusion, reoperation for bleeding, or both? Ann Thorac Surg. 2011;91:1780–1790.
    • (2011) Ann Thorac Surg , vol.91 , pp. 1780-1790
    • Vivacqua, A.1    Koch, C.G.2    Yousuf, A.M.3
  • 7
    • 84961773386 scopus 로고    scopus 로고
    • Reexploration for bleeding and its association with mortality after cardiac surgery
    • Frojd V, Jeppsson A. Reexploration for bleeding and its association with mortality after cardiac surgery. Ann Thorac Surg. 2016;102:109–117.
    • (2016) Ann Thorac Surg , vol.102 , pp. 109-117
    • Frojd, V.1    Jeppsson, A.2
  • 8
    • 77649202241 scopus 로고    scopus 로고
    • Reoperation for bleeding in patients undergoing coronary artery bypass surgery: incidence, risk factors, time trends, and outcomes
    • Mehta RH, Sheng S, O'Brien SM, et al. Reoperation for bleeding in patients undergoing coronary artery bypass surgery:incidence, risk factors, time trends, and outcomes. Circ Cardiovasc Qual Outcomes. 2009;2:583–590.
    • (2009) Circ Cardiovasc Qual Outcomes , vol.2 , pp. 583-590
    • Mehta, R.H.1    Sheng, S.2    O'Brien, S.M.3
  • 9
    • 0029865807 scopus 로고    scopus 로고
    • Reexploration for bleeding is a risk factor for adverse outcomes after cardiac operations
    • Moulton MJ, Creswell LL, Mackey ME, et al. Reexploration for bleeding is a risk factor for adverse outcomes after cardiac operations. J Thorac Cardiovasc Surg. 1996;111:1037–1046.
    • (1996) J Thorac Cardiovasc Surg , vol.111 , pp. 1037-1046
    • Moulton, M.J.1    Creswell, L.L.2    Mackey, M.E.3
  • 10
    • 66349111657 scopus 로고    scopus 로고
    • The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery
    • Surgenor SD, Kramer RS, Olmstead EM, et al. The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery. Anesth Analg. 2009;108:1741–1746.
    • (2009) Anesth Analg , vol.108 , pp. 1741-1746
    • Surgenor, S.D.1    Kramer, R.S.2    Olmstead, E.M.3
  • 11
    • 84924690078 scopus 로고    scopus 로고
    • Liberal or restrictive transfusion after cardiac surgery
    • Murphy GJ, Pike K, Rogers CA, et al. Liberal or restrictive transfusion after cardiac surgery. N Engl J Med. 2015;372:997–1008.
    • (2015) N Engl J Med , vol.372 , pp. 997-1008
    • Murphy, G.J.1    Pike, K.2    Rogers, C.A.3
  • 12
    • 84971619896 scopus 로고    scopus 로고
    • 2015 ESC *Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the
    • Roffi M, Patrono C, Collet JP, et al. 2015 ESC *Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation:Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the. European Society of Cardiology (ESC). Eur Heart J. 2016;37:267–315.
    • (2016) European Society of Cardiology (ESC). Eur Heart J , vol.37 , pp. 267-315
    • Roffi, M.1    Patrono, C.2    Collet, J.P.3
  • 13
    • 84866732231 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
    • Task Force on the Management of STseamiotESoC, Steg PG, James SK, Atar D, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33:2569–2619.
    • (2012) Eur Heart J , vol.33 , pp. 2569-2619
    • Steg, P.G.1    James, S.K.2    Atar, D.3
  • 14
    • 84882700453 scopus 로고    scopus 로고
    • Aspirin A2
    • Michelson A.D., (ed), 3rd ed., New York: Academic Press
    • Patrono C. Aspirin A2. In:Michelson, Alan D, editors. Platelets. 3rd ed. New York:Academic Press; 2013. p. 1099–1115 (Chapter 53).
    • (2013) Platelets , pp. 1099-1115
    • Patrono, C.1
  • 15
    • 84942251246 scopus 로고    scopus 로고
    • Aspirin and coronary artery surgery: a systematic review and meta-analysis
    • Hastings S, Myles P, McIlroy D. Aspirin and coronary artery surgery:a systematic review and meta-analysis. Br J Anaesth. 2015;115:376–385.
    • (2015) Br J Anaesth , vol.115 , pp. 376-385
    • Hastings, S.1    Myles, P.2    McIlroy, D.3
  • 16
    • 0025345221 scopus 로고
    • Antiplatelet treatment with ticlopidine in unstable angina. A controlled multicenter clinical trial. The Studio della Ticlopidina nell'Angina Instabile Group
    • Balsano F, Rizzon P, Violi F, et al. Antiplatelet treatment with ticlopidine in unstable angina. A controlled multicenter clinical trial. The Studio della Ticlopidina nell'Angina Instabile Group. Circulation. 1990;82:17–26.
    • (1990) Circulation , vol.82 , pp. 17-26
    • Balsano, F.1    Rizzon, P.2    Violi, F.3
  • 17
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial I, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494–502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3
  • 18
    • 68949130179 scopus 로고    scopus 로고
    • P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use
    • Wallentin L. P2Y(12) inhibitors:differences in properties and mechanisms of action and potential consequences for clinical use. Eur Heart J. 2009;30:1964–1977.
    • (2009) Eur Heart J , vol.30 , pp. 1964-1977
    • Wallentin, L.1
  • 19
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001–2015.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 20
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009;361:1045–1057.
    • (2009) N Engl J Med , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 21
    • 84864287789 scopus 로고    scopus 로고
    • Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis
    • Smith PK, Goodnough LT, Levy JH, et al. Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort:risk-adjusted retrospective data analysis. J Am Coll Cardiol. 2012;60:388–396.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 388-396
    • Smith, P.K.1    Goodnough, L.T.2    Levy, J.H.3
  • 22
    • 73949112820 scopus 로고    scopus 로고
    • Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study
    • Gurbel PA, Bliden KP, Butler K, et al. Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease:the ONSET/OFFSET study. Circulation. 2009;120:2577–2585.
    • (2009) Circulation , vol.120 , pp. 2577-2585
    • Gurbel, P.A.1    Bliden, K.P.2    Butler, K.3
  • 23
    • 84930958754 scopus 로고    scopus 로고
    • Structural and functional characterization of a specific antidote for ticagrelor
    • Buchanan A, Newton P, Pehrsson S, et al. Structural and functional characterization of a specific antidote for ticagrelor. Blood. 2015;125:3484–3490.
    • (2015) Blood , vol.125 , pp. 3484-3490
    • Buchanan, A.1    Newton, P.2    Pehrsson, S.3
  • 24
    • 82955187874 scopus 로고    scopus 로고
    • Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial
    • Becker RC, Bassand JP, Budaj A, et al. Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. Eur Heart J. 2011;32:2933–2944.
    • (2011) Eur Heart J , vol.32 , pp. 2933-2944
    • Becker, R.C.1    Bassand, J.P.2    Budaj, A.3
  • 25
    • 79551563636 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) Trial
    • Held C, Asenblad N, Bassand JP, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery:results from the PLATO (Platelet Inhibition and Patient Outcomes) Trial. J Am Coll Cardiol. 2011;57:672–684.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 672-684
    • Held, C.1    Asenblad, N.2    Bassand, J.P.3
  • 26
    • 84964614129 scopus 로고    scopus 로고
    • Coronary artery bypass grafting-related bleeding complications in patients treated with ticagrelor or clopidogrel: a nationwide study
    • Hansson EC, Jideus L, Aberg B, et al. Coronary artery bypass grafting-related bleeding complications in patients treated with ticagrelor or clopidogrel:a nationwide study. Eur Heart J. 2016;37:189–197.
    • (2016) Eur Heart J , vol.37 , pp. 189-197
    • Hansson, E.C.1    Jideus, L.2    Aberg, B.3
  • 27
    • 84913619061 scopus 로고    scopus 로고
    • 2014 ESC/EACTS Guidelines on myocardial revascularization
    • Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2014;35:2541–2619.
    • (2014) Eur Heart J , vol.35 , pp. 2541-2619
    • Windecker, S.1    Kolh, P.2    Alfonso, F.3
  • 28
    • 84959421170 scopus 로고    scopus 로고
    • Stopping vs. continuing aspirin before coronary artery surgery
    • Myles PS, Smith JA, Forbes A, et al. Stopping vs. continuing aspirin before coronary artery surgery. N Engl J Med. 2016;374:728–737.
    • (2016) N Engl J Med , vol.374 , pp. 728-737
    • Myles, P.S.1    Smith, J.A.2    Forbes, A.3
  • 29
    • 0034532595 scopus 로고    scopus 로고
    • Effect of preoperative aspirin use on mortality in coronary artery bypass grafting patients
    • Dacey LJ, Munoz JJ, Johnson ER, et al. Effect of preoperative aspirin use on mortality in coronary artery bypass grafting patients. Ann Thorac Surg. 2000;70:1986–1990.
    • (2000) Ann Thorac Surg , vol.70 , pp. 1986-1990
    • Dacey, L.J.1    Munoz, J.J.2    Johnson, E.R.3
  • 30
    • 84862594459 scopus 로고    scopus 로고
    • Effects of preoperative aspirin in coronary artery bypass grafting: a double-blind, placebo-controlled, randomized trial
    • Deja MA, Kargul T, Domaradzki W, et al. Effects of preoperative aspirin in coronary artery bypass grafting:a double-blind, placebo-controlled, randomized trial. J Thorac Cardiovasc Surg. 2012;144:204–209.
    • (2012) J Thorac Cardiovasc Surg , vol.144 , pp. 204-209
    • Deja, M.A.1    Kargul, T.2    Domaradzki, W.3
  • 31
    • 84896813246 scopus 로고    scopus 로고
    • Effects of ex vivo platelet supplementation on platelet aggregability in blood samples from patients treated with acetylsalicylic acid, clopidogrel, or ticagrelor
    • Hansson EC, Shams Hakimi C, Astrom-Olsson K, et al. Effects of ex vivo platelet supplementation on platelet aggregability in blood samples from patients treated with acetylsalicylic acid, clopidogrel, or ticagrelor. Br J Anaesth. 2014;112:570–575.
    • (2014) Br J Anaesth , vol.112 , pp. 570-575
    • Hansson, E.C.1    Shams Hakimi, C.2    Astrom-Olsson, K.3
  • 32
    • 84963930793 scopus 로고    scopus 로고
    • The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation: an in-vitro study
    • Martin AC, Berndt C, Calmette L, et al. The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation:an in-vitro study. Eur J Anaesthesiol. 2016;33:361–367.
    • (2016) Eur J Anaesthesiol , vol.33 , pp. 361-367
    • Martin, A.C.1    Berndt, C.2    Calmette, L.3
  • 33
    • 84947764180 scopus 로고    scopus 로고
    • Efficacy of ex vivo autologous and in vivo platelet transfusion in the reversal of P2Y12 inhibition by clopidogrel, prasugrel, and ticagrelor: the APTITUDE study
    • O'Connor SA, Amour J, Mercadier A, et al. Efficacy of ex vivo autologous and in vivo platelet transfusion in the reversal of P2Y12 inhibition by clopidogrel, prasugrel, and ticagrelor:the APTITUDE study. Circ Cardiovasc Interv. 2015;8:e002786.
    • (2015) Circ Cardiovasc Interv , vol.8 , pp. e002786
    • O'Connor, S.A.1    Amour, J.2    Mercadier, A.3
  • 34
    • 4444229924 scopus 로고    scopus 로고
    • Clopidogrel in unstable angina to prevent Recurrent ischemic Events T. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial
    • Fox KA, Mehta SR, Peters R, et al. Clopidogrel in unstable angina to prevent Recurrent ischemic Events T. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome:the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial. Circulation. 2004;110:1202–1208.
    • (2004) Circulation , vol.110 , pp. 1202-1208
    • Fox, K.A.1    Mehta, S.R.2    Peters, R.3
  • 35
    • 85016125354 scopus 로고    scopus 로고
    • Coronary artery bypass grafting-related bleeding complications in patients treated with dual antiplatelet treatment
    • Tomsic A, Schotborgh MA, Manshanden JS, et al. Coronary artery bypass grafting-related bleeding complications in patients treated with dual antiplatelet treatment. Eur J Cardiothor Surg. 2016 (Epub ahead of print).
    • (2016) Eur J Cardiothor Surg
    • Tomsic, A.1    Schotborgh, M.A.2    Manshanden, J.S.3
  • 36
    • 84869392904 scopus 로고    scopus 로고
    • Stent thrombosis: insights on outcomes, predictors and impact of dual antiplatelet therapy interruption from the SPIRIT II, SPIRIT III, SPIRIT IV and COMPARE trials
    • Kedhi E, Stone GW, Kereiakes DJ, et al. Stent thrombosis:insights on outcomes, predictors and impact of dual antiplatelet therapy interruption from the SPIRIT II, SPIRIT III, SPIRIT IV and COMPARE trials. Eurointervention. 2012;8:599–606.
    • (2012) Eurointervention , vol.8 , pp. 599-606
    • Kedhi, E.1    Stone, G.W.2    Kereiakes, D.J.3
  • 37
    • 84995419062 scopus 로고    scopus 로고
    • Preoperative platelet function predicts perioperative bleeding complications in ticagrelor-treated cardiac surgery patients
    • Malm C, Hansson EC, Åkesson J, et al. Preoperative platelet function predicts perioperative bleeding complications in ticagrelor-treated cardiac surgery patients. Br J Anaesth. 2016;117:309–315.
    • (2016) Br J Anaesth , vol.117 , pp. 309-315
    • Malm, C.1    Hansson, E.C.2    Åkesson, J.3
  • 39
    • 84875124713 scopus 로고    scopus 로고
    • Dual anti-platelet therapy after coronary artery bypass grafting: is there any benefit? A systematic review and meta-analysis
    • Deo SV, Dunlay SM, Shah IK, et al. Dual anti-platelet therapy after coronary artery bypass grafting:is there any benefit? A systematic review and meta-analysis. J Card Surg. 2013;28:109–116.
    • (2013) J Card Surg , vol.28 , pp. 109-116
    • Deo, S.V.1    Dunlay, S.M.2    Shah, I.K.3
  • 40
    • 84944040993 scopus 로고    scopus 로고
    • Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials
    • Verma S, Goodman SG, Mehta SR, et al. Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials. BMC Surg. 2015;15:112.
    • (2015) BMC Surg , vol.15 , pp. 112
    • Verma, S.1    Goodman, S.G.2    Mehta, S.R.3
  • 41
    • 80052397856 scopus 로고    scopus 로고
    • Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses
    • Storey RF, Bliden KP, Ecob R, et al. Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses. J Thromb Haemost. 2011;9:1730–1737.
    • (2011) J Thromb Haemost , vol.9 , pp. 1730-1737
    • Storey, R.F.1    Bliden, K.P.2    Ecob, R.3
  • 42
    • 18044362959 scopus 로고
    • Effect of adenosine diphosphate on the concentration of platelets in circulating blood
    • Born GV, Cross MJ. Effect of adenosine diphosphate on the concentration of platelets in circulating blood. Nature. 1963;197:974–976.
    • (1963) Nature , vol.197 , pp. 974-976
    • Born, G.V.1    Cross, M.J.2
  • 43
    • 84928994249 scopus 로고    scopus 로고
    • The role of point-of-care platelet function testing in predicting postoperative bleeding following cardiac surgery: a systematic review and meta-analysis
    • Corredor C, Wasowicz M, Karkouti K, et al. The role of point-of-care platelet function testing in predicting postoperative bleeding following cardiac surgery:a systematic review and meta-analysis. Anaesthesia. 2015;70:715–731.
    • (2015) Anaesthesia , vol.70 , pp. 715-731
    • Corredor, C.1    Wasowicz, M.2    Karkouti, K.3
  • 44
    • 84940175227 scopus 로고    scopus 로고
    • Preoperative platelet aggregation predicts perioperative blood loss and rethoracotomy for bleeding in patients receiving dual antiplatelet treatment prior to coronary surgery
    • Plicner D, Mazur P, Hymczak H, et al. Preoperative platelet aggregation predicts perioperative blood loss and rethoracotomy for bleeding in patients receiving dual antiplatelet treatment prior to coronary surgery. Thromb Res. 2015;136:519–525.
    • (2015) Thromb Res , vol.136 , pp. 519-525
    • Plicner, D.1    Mazur, P.2    Hymczak, H.3
  • 45
    • 78650465971 scopus 로고    scopus 로고
    • Multiple electrode whole-blood aggregometry and bleeding in cardiac surgery patients receiving thienopyridines
    • Ranucci M, Baryshnikova E, Soro G, et al. Multiple electrode whole-blood aggregometry and bleeding in cardiac surgery patients receiving thienopyridines. Ann Thorac Surg. 2011;91:123–129.
    • (2011) Ann Thorac Surg , vol.91 , pp. 123-129
    • Ranucci, M.1    Baryshnikova, E.2    Soro, G.3
  • 46
    • 84925225538 scopus 로고    scopus 로고
    • Effect of preoperative P2Y12 and thrombin platelet receptor inhibition on bleeding after cardiac surgery
    • Ranucci M, Colella D, Baryshnikova E, et al. Effect of preoperative P2Y12 and thrombin platelet receptor inhibition on bleeding after cardiac surgery. Br J Anaesth. 2014;113:970–976.
    • (2014) Br J Anaesth , vol.113 , pp. 970-976
    • Ranucci, M.1    Colella, D.2    Baryshnikova, E.3
  • 47
    • 84860789698 scopus 로고    scopus 로고
    • Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study
    • Mahla E, Suarez TA, Bliden KP, et al. Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery:the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study. Circ Cardiovasc Interv. 2012;5:261–269.
    • (2012) Circ Cardiovasc Interv , vol.5 , pp. 261-269
    • Mahla, E.1    Suarez, T.A.2    Bliden, K.P.3
  • 48
    • 84928944621 scopus 로고    scopus 로고
    • Long-term use of ticagrelor in patients with prior myocardial infarction
    • Bonaca MP, Bhatt DL, Cohen M, et al. Long-term use of ticagrelor in patients with prior myocardial infarction. N Engl J Med. 2015;372:1791–1800.
    • (2015) N Engl J Med , vol.372 , pp. 1791-1800
    • Bonaca, M.P.1    Bhatt, D.L.2    Cohen, M.3
  • 49
    • 84856023997 scopus 로고    scopus 로고
    • Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: a randomized controlled trial
    • Angiolillo DJ, Firstenberg MS, Price MJ, et al. Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery:a randomized controlled trial. J Am Med Assoc. 2012;307:265–274.
    • (2012) J Am Med Assoc , vol.307 , pp. 265-274
    • Angiolillo, D.J.1    Firstenberg, M.S.2    Price, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.