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Volumn 6, Issue 4, 2016, Pages 332-336

Cinnamon extract lowers glucose, insulin and cholesterol in people with elevated serum glucose

Author keywords

Cinnamon; Glucose; Insulin sensitivity; Lipids; Type A procyanidin polyphenols

Indexed keywords


EID: 84992195855     PISSN: None     EISSN: 22254110     Source Type: Journal    
DOI: 10.1016/j.jtcme.2015.03.005     Document Type: Article
Times cited : (105)

References (46)
  • 2
    • 0345707504 scopus 로고    scopus 로고
    • Cinnamon improves glucose and lipids of people with type 2 diabetes
    • 2 Khan, A., Safdar, M., Ali Khan, M.M., Khattak, K.N., Anderson, R.A., Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 26 (2003), 3215–3218.
    • (2003) Diabetes Care , vol.26 , pp. 3215-3218
    • Khan, A.1    Safdar, M.2    Ali Khan, M.M.3    Khattak, K.N.4    Anderson, R.A.5
  • 3
    • 38749133281 scopus 로고    scopus 로고
    • Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women
    • 3 Ziegenfuss, T.N., Hofheins, J.E., Mendel, R.W., Landis, J., Anderson, R.A., Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 3 (2006), 45–53.
    • (2006) J Int Soc Sports Nutr , vol.3 , pp. 45-53
    • Ziegenfuss, T.N.1    Hofheins, J.E.2    Mendel, R.W.3    Landis, J.4    Anderson, R.A.5
  • 4
    • 33645893174 scopus 로고    scopus 로고
    • Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2
    • 4 Mang, B., Wolters, M., Schmitt, B., et al. Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2. Eur J Clin Invest 36 (2006), 340–344.
    • (2006) Eur J Clin Invest , vol.36 , pp. 340-344
    • Mang, B.1    Wolters, M.2    Schmitt, B.3
  • 5
    • 69449100511 scopus 로고    scopus 로고
    • Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese
    • 5 Roussel, A.M., Hininger, I., Benaraba, R., Ziegenfuss, T.N., Anderson, R.A., Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr 28 (2009), 16–21.
    • (2009) J Am Coll Nutr , vol.28 , pp. 16-21
    • Roussel, A.M.1    Hininger, I.2    Benaraba, R.3    Ziegenfuss, T.N.4    Anderson, R.A.5
  • 6
    • 35048893744 scopus 로고    scopus 로고
    • Effects of short-term cinnamon ingestion on in vivo glucose tolerance
    • 6 Solomon, T.P., Blannin, A.K., Effects of short-term cinnamon ingestion on in vivo glucose tolerance. Diabetes Obes Metab 9 (2007), 895–901.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 895-901
    • Solomon, T.P.1    Blannin, A.K.2
  • 7
    • 34250001148 scopus 로고    scopus 로고
    • Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects
    • 7 Hlebowicz, J., Darwiche, G., Bjorgell, O., Almer, L.O., Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. Am J Clin Nutr 85 (2007), 1552–1556.
    • (2007) Am J Clin Nutr , vol.85 , pp. 1552-1556
    • Hlebowicz, J.1    Darwiche, G.2    Bjorgell, O.3    Almer, L.O.4
  • 8
    • 61449114791 scopus 로고    scopus 로고
    • Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects
    • 8 Hlebowicz, J., Hlebowicz, A., Lindstedt, S., et al. Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects. Am J Clin Nutr 89 (2009), 815–821.
    • (2009) Am J Clin Nutr , vol.89 , pp. 815-821
    • Hlebowicz, J.1    Hlebowicz, A.2    Lindstedt, S.3
  • 9
    • 70349140462 scopus 로고    scopus 로고
    • Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial
    • 9 Crawford, P., Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 22 (2009), 507–512.
    • (2009) J Am Board Fam Med , vol.22 , pp. 507-512
    • Crawford, P.1
  • 10
    • 77956863768 scopus 로고    scopus 로고
    • Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial
    • 10 Akilen, R., Tsiami, A., Devendra, D., Robinson, N., Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet Med 27 (2010), 1159–1167.
    • (2010) Diabet Med , vol.27 , pp. 1159-1167
    • Akilen, R.1    Tsiami, A.2    Devendra, D.3    Robinson, N.4
  • 11
    • 84865089514 scopus 로고    scopus 로고
    • Effects of cinnamon consumption on glycemic status, lipid profile and body composition in type 2 diabetic patients
    • 11 Vafa, M., Mohammadi, F., Shidfar, F., et al. Effects of cinnamon consumption on glycemic status, lipid profile and body composition in type 2 diabetic patients. Int J Prev Med 3 (2012), 531–536.
    • (2012) Int J Prev Med , vol.3 , pp. 531-536
    • Vafa, M.1    Mohammadi, F.2    Shidfar, F.3
  • 12
    • 84867960036 scopus 로고    scopus 로고
    • Effect of ground cinnamon on postprandial blood glucose concentration in normal-weight and obese adults
    • 12 Magistrelli, A., Chezem, J.C., Effect of ground cinnamon on postprandial blood glucose concentration in normal-weight and obese adults. J Acad Nutr Diet 112 (2012), 1806–1809.
    • (2012) J Acad Nutr Diet , vol.112 , pp. 1806-1809
    • Magistrelli, A.1    Chezem, J.C.2
  • 13
    • 84863092148 scopus 로고    scopus 로고
    • Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes
    • 13 Lu, T., Sheng, H., Wu, J., Cheng, Y., Zhu, J., Chen, Y., Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res 32 (2012), 408–412.
    • (2012) Nutr Res , vol.32 , pp. 408-412
    • Lu, T.1    Sheng, H.2    Wu, J.3    Cheng, Y.4    Zhu, J.5    Chen, Y.6
  • 14
    • 80052007192 scopus 로고    scopus 로고
    • Cinnamon intake lowers fasting blood glucose: meta-analysis
    • 14 Davis, P.A., Yokoyama, W., Cinnamon intake lowers fasting blood glucose: meta-analysis. J Med Food 14 (2011), 884–889.
    • (2011) J Med Food , vol.14 , pp. 884-889
    • Davis, P.A.1    Yokoyama, W.2
  • 15
    • 84883813787 scopus 로고    scopus 로고
    • Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis
    • 15 Allen, R.W., Schwartzman, E., Baker, W.L., Coleman, C.I., Phung, O.J., Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis. Ann Fam Med 11 (2013), 452–459.
    • (2013) Ann Fam Med , vol.11 , pp. 452-459
    • Allen, R.W.1    Schwartzman, E.2    Baker, W.L.3    Coleman, C.I.4    Phung, O.J.5
  • 17
    • 77950263954 scopus 로고    scopus 로고
    • Prevalence of diabetes among men and women in China
    • 17 Yang, W., Lu, J., Weng, J., et al. Prevalence of diabetes among men and women in China. N Engl J Med 362 (2010), 1090–1101.
    • (2010) N Engl J Med , vol.362 , pp. 1090-1101
    • Yang, W.1    Lu, J.2    Weng, J.3
  • 18
    • 84888610885 scopus 로고    scopus 로고
    • ethical principles for medical research involving human subjects
    • 18 World Medical Association Declaration of Helsinki, ethical principles for medical research involving human subjects. JAMA 310 (2013), 2191–2194.
    • (2013) JAMA , vol.310 , pp. 2191-2194
    • World Medical Association Declaration of Helsinki1
  • 19
    • 0346724515 scopus 로고    scopus 로고
    • Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity
    • 19 Anderson, R.A., Broadhurst, C.L., Polansky, M.M., et al. Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. J Agric Food Chem 52 (2004), 65–70.
    • (2004) J Agric Food Chem , vol.52 , pp. 65-70
    • Anderson, R.A.1    Broadhurst, C.L.2    Polansky, M.M.3
  • 20
    • 0034117424 scopus 로고    scopus 로고
    • Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro
    • 20 Broadhurst, C.L., Polansky, M.M., Anderson, R.A., Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 48 (2000), 849–852.
    • (2000) J Agric Food Chem , vol.48 , pp. 849-852
    • Broadhurst, C.L.1    Polansky, M.M.2    Anderson, R.A.3
  • 21
    • 0031666543 scopus 로고    scopus 로고
    • Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling
    • 21 Imparl-Radosevich, J., Deas, S., Polansky, M.M., et al. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res 50 (1998), 177–182.
    • (1998) Horm Res , vol.50 , pp. 177-182
    • Imparl-Radosevich, J.1    Deas, S.2    Polansky, M.M.3
  • 22
    • 0034885329 scopus 로고    scopus 로고
    • A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes
    • 22 Jarvill-Taylor, K.J., Anderson, R.A., Graves, D.J., A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 20 (2001), 327–336.
    • (2001) J Am Coll Nutr , vol.20 , pp. 327-336
    • Jarvill-Taylor, K.J.1    Anderson, R.A.2    Graves, D.J.3
  • 24
    • 33846703632 scopus 로고    scopus 로고
    • Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes
    • 24 Cao, H., Polansky, M.M., Anderson, R.A., Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes. Arch Biochem Biophys 459 (2007), 214–222.
    • (2007) Arch Biochem Biophys , vol.459 , pp. 214-222
    • Cao, H.1    Polansky, M.M.2    Anderson, R.A.3
  • 25
    • 42449100683 scopus 로고    scopus 로고
    • Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages
    • 25 Cao, H., Urban, J.F. Jr., Anderson, R.A., Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages. J Nutr 138 (2008), 833–840.
    • (2008) J Nutr , vol.138 , pp. 833-840
    • Cao, H.1    Urban, J.F.2    Anderson, R.A.3
  • 26
    • 0036481323 scopus 로고    scopus 로고
    • Predictive values of body mass index and waist circumference to risk factors of related diseases in Chinese adult population
    • 26 Zhou, B., Predictive values of body mass index and waist circumference to risk factors of related diseases in Chinese adult population. Zhonghua Liu Xing Bing Xue Za Zhi 23 (2002), 5–10.
    • (2002) Zhonghua Liu Xing Bing Xue Za Zhi , vol.23 , pp. 5-10
    • Zhou, B.1
  • 28
    • 84933511764 scopus 로고    scopus 로고
    • Diabetes in China: a societal solution for a personal challenge
    • 28 Chan, J.C., Zhang, Y., Ning, G., Diabetes in China: a societal solution for a personal challenge. Lancet Diabetes Endocrinol 2 (2014), 969–979.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 969-979
    • Chan, J.C.1    Zhang, Y.2    Ning, G.3
  • 30
    • 84878858655 scopus 로고    scopus 로고
    • Progression rates from HbA1c 6.0-6.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis
    • 30 Morris, D.H., Khunti, K., Achana, F., et al. Progression rates from HbA1c 6.0-6.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis. Diabetologia 56 (2013), 1489–1493.
    • (2013) Diabetologia , vol.56 , pp. 1489-1493
    • Morris, D.H.1    Khunti, K.2    Achana, F.3
  • 31
    • 65349086103 scopus 로고    scopus 로고
    • Progression to impaired glucose regulation and diabetes in the population-based Inter99 study
    • 31 Engberg, S., Vistisen, D., Lau, C., et al. Progression to impaired glucose regulation and diabetes in the population-based Inter99 study. Diabetes Care 32 (2009), 606–611.
    • (2009) Diabetes Care , vol.32 , pp. 606-611
    • Engberg, S.1    Vistisen, D.2    Lau, C.3
  • 32
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • 32 Knowler, W.C., Barrett-Connor, E., Fowler, S.E., et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346 (2002), 393–403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 33
    • 33646574976 scopus 로고    scopus 로고
    • Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial
    • 33 Chiasson, J.L., Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial. Endocr Pract 1:12 suppl (2006), 25–30.
    • (2006) Endocr Pract , vol.1 , Issue.12 , pp. 25-30
    • Chiasson, J.L.1
  • 34
    • 79953232077 scopus 로고    scopus 로고
    • Pioglitazone for diabetes prevention in impaired glucose tolerance
    • 34 DeFronzo, R.A., Tripathy, D., Schwenke, D.C., et al. Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med 364 (2011), 1104–1115.
    • (2011) N Engl J Med , vol.364 , pp. 1104-1115
    • DeFronzo, R.A.1    Tripathy, D.2    Schwenke, D.C.3
  • 36
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: the link between insulin resistance, obesity and diabetes
    • 36 Dandona, P., Aljada, A., Bandyopadhyay, A., Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 25 (2004), 4–7.
    • (2004) Trends Immunol , vol.25 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 37
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • 37 Dandona, P., Aljada, A., Chaudhuri, A., Mohanty, P., Garg, R., Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111 (2005), 1448–1454.
    • (2005) Circulation , vol.111 , pp. 1448-1454
    • Dandona, P.1    Aljada, A.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5
  • 38
    • 55249117106 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance significantly correlate with body mass index
    • 38 Esteghamati, A., Khalilzadeh, O., Anvari, M., Ahadi, M.S., Abbasi, M., Rashidi, A., Metabolic syndrome and insulin resistance significantly correlate with body mass index. Arch Med Res 39 (2008), 803–808.
    • (2008) Arch Med Res , vol.39 , pp. 803-808
    • Esteghamati, A.1    Khalilzadeh, O.2    Anvari, M.3    Ahadi, M.S.4    Abbasi, M.5    Rashidi, A.6
  • 39
    • 0141863402 scopus 로고    scopus 로고
    • Overview of dietary flavonoids: nomenclature, occurrence and intake
    • 39 Beecher, G.R., Overview of dietary flavonoids: nomenclature, occurrence and intake. J Nutr 133 (2003), 3248S–3254S.
    • (2003) J Nutr , vol.133 , pp. 3248S-3254S
    • Beecher, G.R.1
  • 40
    • 41849141611 scopus 로고    scopus 로고
    • Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts
    • 40 Peng, X., Cheng, K.W., Ma, J., et al. Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. J Agric Food Chem 56 (2008), 1907–1911.
    • (2008) J Agric Food Chem , vol.56 , pp. 1907-1911
    • Peng, X.1    Cheng, K.W.2    Ma, J.3
  • 41
    • 84865310823 scopus 로고    scopus 로고
    • In vivo and in vitro antidiabetic effects of aqueous cinnamon extract and cinnamon polyphenol-enhanced food matrix
    • 41 Cheng, D.M., Kuhn, P., Poulev, A., Rojo, L.E., Lila, M.A., Raskin, I., In vivo and in vitro antidiabetic effects of aqueous cinnamon extract and cinnamon polyphenol-enhanced food matrix. Food Chem 135 (2012), 2994–3002.
    • (2012) Food Chem , vol.135 , pp. 2994-3002
    • Cheng, D.M.1    Kuhn, P.2    Poulev, A.3    Rojo, L.E.4    Lila, M.A.5    Raskin, I.6
  • 42
    • 0038645828 scopus 로고    scopus 로고
    • The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation
    • 42 Gurnell, M., Savage, D.B., Chatterjee, V.K., O'Rahilly, S., The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation. J Clin Endocrinol Metab 88 (2003), 2412–2421.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2412-2421
    • Gurnell, M.1    Savage, D.B.2    Chatterjee, V.K.3    O'Rahilly, S.4
  • 43
    • 79953024415 scopus 로고    scopus 로고
    • PPARalpha activation by culinary herbs and spices
    • 43 Mueller, M., Beck, V., Jungbauer, A., PPARalpha activation by culinary herbs and spices. Planta Med 77 (2011), 497–504.
    • (2011) Planta Med , vol.77 , pp. 497-504
    • Mueller, M.1    Beck, V.2    Jungbauer, A.3
  • 44
    • 77949884990 scopus 로고    scopus 로고
    • Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice
    • 44 Kim, S.H., Choung, S.Y., Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice. Arch Pharm Res 33 (2010), 325–333.
    • (2010) Arch Pharm Res , vol.33 , pp. 325-333
    • Kim, S.H.1    Choung, S.Y.2
  • 45
    • 77956179596 scopus 로고    scopus 로고
    • Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes
    • 45 Qin, B., Panickar, K.S., Anderson, R.A., Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. J Diabetes Sci Technol 4 (2010), 685–693.
    • (2010) J Diabetes Sci Technol , vol.4 , pp. 685-693
    • Qin, B.1    Panickar, K.S.2    Anderson, R.A.3
  • 46
    • 70149094195 scopus 로고    scopus 로고
    • Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes
    • 46 Qin, B., Dawson, H., Polansky, M.M., Anderson, R.A., Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes. Horm Metab Res 41 (2009), 516–522.
    • (2009) Horm Metab Res , vol.41 , pp. 516-522
    • Qin, B.1    Dawson, H.2    Polansky, M.M.3    Anderson, R.A.4


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