DNA-guided genome editing using structure-guided endonucleases

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Varshney, Gaurav K ^a   Burgess, Shawn M ^b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; MEMBRANE PROTEIN; PROTEIN FOK1; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE; DNA; ENDONUCLEASE; GUIDE RNA;

ARTICLE; CRISPR CAS SYSTEM; DNA MODIFICATION; DNA STRUCTURE; GENE DELETION; GENE TARGETING; GENETIC ANALYSIS; GENETIC ENGINEERING; HUMAN; NATRONOBACTERIUM GREGORYI; NONHUMAN; PROTEIN STRUCTURE; ANIMAL; CHEMISTRY; GENE EDITING; GENETICS; GENOME; METABOLISM;

ANIMALS; CRISPR-CAS SYSTEMS; DNA; ENDONUCLEASES; GENE EDITING; GENOME; RNA, GUIDE;

EID: 84992154293     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1055-4     Document Type: Article

References (9)

1. Xu S, Cao S, Zou B, Yue Y, Gu C, Chen X, et al. An alternative novel tool for DNA editing without target sequence limitation: the structure-guided nuclease (SGN). Genome Biol. 2016. doi: 10.1186/s13059-016-1038-5.
2. Kim H, Kim JS. A guide to genome engineering with programmable nucleases. Nat Rev Genet. 2014;15:321-34.
3. Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science. 2012;337:816-21.
4. Sander JD, Joung JK. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat Biotechnol. 2014;32:347-55.
5. Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 2014;157:1262-78.
6. Mohanraju P, Makarova KS, Zetsche B, Zhang F, Koonin EV, van der Oost J. Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems. Science. 2016;353:aad5147.
7. Gao F, Shen XZ, Jiang F, Wu Y, Han C. DNA-guided genome editing using the Natronobacterium gregoryi Argonaute. Nat Biotechnol. 2016;34:768-73.
8. Swarts DC, Jore MM, Westra ER, Zhu Y, Janssen JH, Snijders AP. DNA-guided DNA interference by a prokaryotic Argonaute. Nature. 2014;507:258-61.
9. Cyranoski D. Replications, ridicule and a recluse: the controversy over NgAgo gene-editing intensifies. Nature. 2016;536:136-7.