Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production

Stem Cell Research and Therapy

Volumn 7, Issue 1, 2016, Pages 1-16

  Camilleri, Emily T ^a   Gustafson, Michael P ^a   Dudakovic, Amel ^a   Riester, Scott M ^a   Garces, Catalina Galeano ^a   Paradise, Christopher R ^a   Takai, Hideki ^b   Karperien, Marcel ^c   Cool, Simon ^d,e   Sampen, Hee Jeong Im ^f,g   Larson, A Noelle ^a   Qu, Wenchun ^a   Smith, Jay ^a   Dietz, Allan B ^a   Van Wijnen, Andre J ^a,h  

^a MAYO CLINIC   (United States)

^b NIHON UNIVERSITY   (Japan)

^c UNIVERSITY OF TWENTE   (Netherlands)

^d INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f RUSH UNIVERSITY MEDICAL CENTER   (United States)

^g JESSE BROWN VA MEDICAL CENTER   (United States)

^h MAYO GRADUATE SCHOOL   (United States)

Author keywords

Adipose derived mesenchymal stromal cells; CD markers; Flow cytometry; Human platelet lysate; Manufacturing; Release criteria; RNA sequencing

Indexed keywords

5' NUCLEOTIDASE; ANTIBODY; CD14 ANTIGEN; CD146 ANTIGEN; CD163 ANTIGEN; CD200 ANTIGEN; CD276 ANTIBODY; CD34 ANTIBODY; CD36 ANTIGEN; CD45 ANTIGEN; ENDOGLIN; ENDOSIALIN; HERMES ANTIGEN; HLA ANTIGEN; HLA DR ANTIGEN; NEUROTROPHIN RECEPTOR P75; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; THY 1 ANTIGEN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; TRANSCRIPTOME;

ADIPOSE DERIVED MESENCHYMAL STROMAL CELL; ADIPOSE TISSUE CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MESENCHYMAL STROMA CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; THROMBOCYTE; ADIPOSE TISSUE; BONE MARROW CELL; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; METABOLISM; OBESITY; PHYSIOLOGY; PROCEDURES; SEQUENCE ANALYSIS;

ADIPOSE TISSUE; ADIPOSITY; BIOMARKERS; BONE MARROW CELLS; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; MESENCHYMAL STROMAL CELLS; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 84992153981     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/s13287-016-0370-8     Document Type: Article

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