Dying with a Left Ventricular Assist Device as Destination Therapy

Circulation: Heart Failure

Volumn 9, Issue 10, 2016, Pages

  Dunlay, Shannon M ^a,c   Strand, Jacob J ^b   Wordingham, Sara E ^d   Stulak, John M ^a   Luckhardt, Angela J ^b   Swetz, Keith M ^e  

^a Division of Health Care Policy and Research   (United States)

^b Division of General Internal Medicine   (United States)

^c MAYO CLINIC   (United States)

^d MAYO CLINIC   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

end of life care; heart failure; left ventricular assist device; morbidity mortality

Indexed keywords

ADULT; ARTICLE; BRAIN HEMORRHAGE; CAUSE OF DEATH; DEATH; DISEASE COURSE; FEMALE; HEART FAILURE; HOSPICE CARE; HUMAN; INTENSIVE CARE UNIT; LEFT VENTRICULAR ASSIST DEVICE; MALE; MULTIPLE ORGAN FAILURE; PALLIATIVE THERAPY; PRIORITY JOURNAL; AGED; CEREBROVASCULAR ACCIDENT; HEART ASSIST DEVICE; MIDDLE AGED; PATIENT REFERRAL; RETROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; SURVIVAL RATE; TERMINAL CARE; TREATMENT WITHDRAWAL; UTILIZATION;

AGED; CAUSE OF DEATH; DISEASE PROGRESSION; FEMALE; HEART FAILURE; HEART-ASSIST DEVICES; HOSPICE CARE; HUMANS; INTENSIVE CARE UNITS; INTRACRANIAL HEMORRHAGES; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; PALLIATIVE CARE; REFERRAL AND CONSULTATION; RETROSPECTIVE STUDIES; STROKE; SURVIVAL RATE; TERMINAL CARE; WITHHOLDING TREATMENT;

EID: 84992055568     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.116.003096     Document Type: Article

References (21)

1. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL; Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435-1443. doi: 10.1056/NEJMoa012175.
2. Kato NP, Okada I, Imamura T, Kagami Y, Endo M, Nitta D, Fujino T, Muraoka H, Minatsuki S, Maki H, Inaba T, Kinoshita O, Nawata K, Hatano M, Yao A, Kyo S, Ono M, Jaarsma T, Kinugawa K. Quality of Life and Influential Factors in Patients Implanted With a Left Ventricular Assist Device. Circ J. 2015;79:2186-2192. doi: 10.1253/circj. CJ-15-0502.
3. McIlvennan CK, Magid KH, Ambardekar AV, Thompson JS, Matlock DD, Allen LA. Clinical outcomes after continuous-flow left ventricular assist device: a systematic review. Circ Heart Fail. 2014;7:1003-1013. doi: 10.1161/CIRCHEARTFAILURE.114.001391.
4. Dunlay SM, Redfield MM, Jiang R, Weston SA, Roger VL. Care in the last year of life for community patients with heart failure. Circ Heart Fail. 2015;8:489-496. doi: 10.1161/CIRCHEARTFAILURE.114. 001826.
5. Mueller PS, Swetz KM, Freeman MR, Carter KA, Crowley ME, Severson CJ, Park SJ, Sulmasy DP. Ethical analysis of withdrawing ventricular assist device support. Mayo Clin Proc. 2010;85:791-797. doi: 10.4065/mcp.2010.0113.
6. Stulak JM, Mehta V, Schirger JA, Aaronson KD, Joyce LD, Daly RC, Pagani FD, Maltais S. Temporal differences in causes of mortality after left ventricular assist device implantation. Ann Thorac Surg. 2015;99:1969-1972; discussion 1972. doi: 10.1016/j.athoracsur.2015. 01.036.
7. Lietz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers JG, Naka Y, Mancini D, Miller LW. Outcomes of left ventricular assist device implantation as destination therapy in the post-REMATCH era: implications for patient selection. Circulation. 2007;116:497-505. doi: 10.1161/CIRCULATIONAHA.107.691972.
8. Feldman D, Pamboukian SV, Teuteberg JJ, Birks E, Lietz K, Moore SA, Morgan JA, Arabia F, Bauman ME, Buchholz HW, Deng M, Dickstein ML, El-Banayosy A, Elliot T, Goldstein DJ, Grady KL, Jones K, Hryniewicz K, John R, Kaan A, Kusne S, Loebe M, Massicotte MP, Moazami N, Mohacsi P, Mooney M, Nelson T, Pagani F, Perry W, Potapov EV, Eduardo Rame J, Russell SD, Sorensen EN, Sun B, Strueber M, Mangi AA, Petty MG, Rogers J; International Society for Heart and Lung Transplantation. The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant. 2013;32:157-187. doi: 10.1016/j.healun.2012.09.013.
9. Rady MY, Verheijde JL. Ethical challenges with deactivation of durable mechanical circulatory support at the end of life: left ventricular assist devices and total artificial hearts. J Intensive Care Med. 2014;29:3-12. doi: 10.1177/0885066611432415.
10. Rizzieri AG, Verheijde JL, Rady MY, McGregor JL. Ethical challenges with the left ventricular assist device as a destination therapy. Philos Ethics Humanit Med. 2008;3:20. doi: 10.1186/1747-5341-3-20.
11. Murray SA, Kendall M, Boyd K, Sheikh A. Illness trajectories and palliative care. BMJ. 2005;330:1007-1011. doi: 10.1136/bmj.330. 7498.1007.
12. Khazanie P, Hammill BG, Patel CB, Eapen ZJ, Peterson ED, Rogers JG, Milano CA, Curtis LH, Hernandez AF. Trends in the use and outcomes of ventricular assist devices among medicare beneficiaries, 2006 through 2011. J Am Coll Cardiol. 2014;63:1395-1404. doi: 10.1016/j. jacc.2013.12.020.
13. Verdoorn B, Swetz KM, Luckhardt AJ, Dunlay SM. Preparedness planning for patients receiving left ventricular assist device as destination therapy: how best to measure change in culture? J Pain Symptom Manage. 2015;40:404-405.
14. Unroe KT, Greiner MA, Hernandez AF, Whellan DJ, Kaul P, Schulman KA, Peterson ED, Curtis LH. Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000-2007. Arch Intern Med. 2011;171:196-203. doi: 10.1001/archinternmed. 2010.371.
15. Teno JM, Gozalo PL, Bynum JP, Leland NE, Miller SC, Morden NE, Scupp T, Goodman DC, Mor V. Change in end-of-life care for Medicare beneficiaries: site of death, place of care, and health care transitions in 2000, 2005, and 2009. JAMA. 2013;309:470-477. doi: 10.1001/jama.2012.207624.
16. Wright AA, Keating NL, Balboni TA, Matulonis UA, Block SD, Prigerson HG. Place of death: correlations with quality of life of patients with cancer and predictors of bereaved caregivers' mental health. J Clin Oncol. 2010;28:4457-4464. doi: 10.1200/JCO.2009.26.3863.
17. Teno JM, Clarridge BR, Casey V, Welch LC, Wetle T, Shield R, Mor V. Family perspectives on end-of-life care at the last place of care. JAMA. 2004;291:88-93. doi: 10.1001/jama.291.1.88.
18. Dunlay SM, Foxen JL, Cole T, Feely MA, Loth AR, Strand JJ, Wagner JA, Swetz KM, Redfield MM. A survey of clinician attitudes and self-reported practices regarding end-of-life care in heart failure. Palliat Med. 2015;29:260-267. doi: 10.1177/0269216314556565.
19. Brush S, Budge D, Alharethi R, McCormick AJ, MacPherson JE, Reid BB, Ledford ID, Smith HK, Stoker S, Clayson SE, Doty JR, Caine WT, Drakos S, Kfoury AG. End-of-life decision making and implementation in recipients of a destination left ventricular assist device. J Heart Lung Transplant. 2010;29:1337-1341. doi: 10.1016/j.healun.2010.07.001.
20. Gafford EF, Luckhardt AJ, Swetz KM. Deactivation of a left ventricular assist device at the end of life #269. J Palliat Med. 2013;16:980-982. doi: 10.1089/jpm.2013.9490.
21. McIlvennan CK, Jones J, Allen LA, Swetz KM, Nowels C, Matlock DD. Bereaved Caregiver Perspectives on the End-of-Life Experience of Patients With a Left Ventricular Assist Device. JAMA Intern Med. 2016;176:534-539. doi: 10.1001/jamainternmed.2015.8528.