NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

Oncotarget

Volumn 7, Issue 27, 2016, Pages 41251-41264

  Yahyanejad, Sanaz ^a   King, Henry ^a   Iglesias, Venus Sosa ^a   Granton, Patrick V ^a   Barbeau, Lydie M O ^a   van Hoof, Stefan J ^a   Groot, Arjan J ^a   Habets, Roger ^a   Prickaerts, Jos ^a   Chalmers, Anthony J ^a   Eekers, Daniëlle B P ^a   Theys, Jan ^a   Short, Susan C ^a   Verhaegen, Frank ^a   Vooijs, Marc ^a  

^a MAASTRO CLINIC   (Netherlands)

Author keywords

glioblastoma; glioma stem cells; image guidance radiotherapy; RO4929097 NOTCH inhibitor; temozolomide

Indexed keywords

2,2-DIMETHYL-N-(6-OXO-6,7-DIHYDRO-5H-DIBENZO(B,D)AZEPIN-7-YL)-N'-(2,2,3,3,3-PENTAFLUOROPROPYL)MALONAMIDE; ANTINEOPLASTIC AGENT; BENZAZEPINE DERIVATIVE; DACARBAZINE; NOTCH RECEPTOR; TEMOZOLOMIDE;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CHEMORADIOTHERAPY; DRUG SCREENING; GLIOBLASTOMA; HUMAN; MORTALITY; MOUSE; NUDE MOUSE; PATHOLOGY; PROCEDURES; SURVIVAL ANALYSIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BENZAZEPINES; BRAIN NEOPLASMS; CELL LINE, TUMOR; CHEMORADIOTHERAPY; DACARBAZINE; GLIOBLASTOMA; HUMANS; MICE; MICE, NUDE; RECEPTORS, NOTCH; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84991762680     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9275     Document Type: Article

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